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ID 8 - 98%, high purity , CAS No.147591-46-6

COA COA
    Grade & Purity:
  • ≥98%
In stock
Item Number
I287101
Grouped product items
SKU Size
Availability
 Price Qty
I287101-5mg
5mg
5
$48.90
I287101-10mg
10mg
4
$68.90
I287101-25mg
25mg
3
$155.90
I287101-50mg
50mg
2
$197.90
I287101-100mg
100mg
1
$355.90
I287101-250mg
250mg
1
$801.90
I287101-1g
1g
1
$2,883.90
Wish List
Bulk Order  SDS  DATASHEET  Specification Sheet

Sustains self-renewal and pluripotency of ESCs

View related series
DYRK (39) Non-receptor Tyrosine Kinase (643) Protein Tyrosine Kinase/RTK (1314)

Basic Description

Synonyms BCP27795 | ID-8 | VVZNWYXIOADGSW-UHFFFAOYSA-N | 1H-Indol-6-ol, 1-(4-methoxyphenyl)-2-methyl-3-nitro- | AKOS000558433 | MLS006011013 | 3-nitro-1-(4-methoxyphenyl)-2-methyl-1H-indol-6-ol | CBDivE_013358 | FT-0729107 | ID-8, >=98% (HPLC) | J-008372 | SW22013
Specifications & Purity ≥98%
Biochemical and Physiological Mechanisms Sustains self-renewal and pluripotency of mouse embryonic stem cells (ESCs)in vitro. Stimulates proliferation at a steady rate (observed in serum-free media supplemented with 10μM over a 30 day period). Also supports human PSC maintenance in combiantions
Storage Temp Protected from light,Store at -20°C
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
Superclass Organoheterocyclic compounds
Class Pyrroles
Subclass Substituted pyrroles
Intermediate Tree Nodes Not available
Direct Parent Phenylpyrroles
Alternative Parents Hydroxyindoles  Indoles  Methoxyanilines  Phenoxy compounds  Anisoles  Nitroaromatic compounds  Methoxybenzenes  1-hydroxy-2-unsubstituted benzenoids  Alkyl aryl ethers  Heteroaromatic compounds  Organic oxoazanium compounds  Propargyl-type 1,3-dipolar organic compounds  Azacyclic compounds  Organic zwitterions  Hydrocarbon derivatives  Organonitrogen compounds  Organopnictogen compounds  Organic oxides  
Molecular Framework Aromatic heteropolycyclic compounds
Substituents 1-phenylpyrrole - Hydroxyindole - Methoxyaniline - Indole or derivatives - Indole - Phenol ether - Phenoxy compound - Methoxybenzene - Nitroaromatic compound - Anisole - 1-hydroxy-2-unsubstituted benzenoid - Alkyl aryl ether - Benzenoid - Monocyclic benzene moiety - Heteroaromatic compound - C-nitro compound - Organic nitro compound - Ether - Azacycle - Organic oxoazanium - Organic 1,3-dipolar compound - Propargyl-type 1,3-dipolar organic compound - Allyl-type 1,3-dipolar organic compound - Organic oxygen compound - Hydrocarbon derivative - Organonitrogen compound - Organooxygen compound - Organopnictogen compound - Organic nitrogen compound - Organic zwitterion - Organic oxide - Aromatic heteropolycyclic compound
Description This compound belongs to the class of organic compounds known as phenylpyrroles. These are polycyclic aromatic compounds containing a benzene ring linked to a pyrrole ring through a CC or CN bond.
External Descriptors Not available

Associated Targets(Human)

ABL1 Tclin Tyrosine-protein kinase ABL (18331 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
GSK3B Tclin Glycogen synthase kinase-3 beta (11785 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CSNK1D Tchem Casein kinase I delta (4546 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CSNK1E Tclin Casein kinase I epsilon (1412 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CDK2 Tchem Cyclin-dependent kinase 2 (9050 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
DYRK1A Tchem Dual-specificity tyrosine-phosphorylation regulated kinase 1A (6484 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
AURKA Tchem Serine/threonine-protein kinase Aurora-A (10240 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CLK1 Tchem Dual specificty protein kinase CLK1 (2189 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CLK2 Tchem Dual specificity protein kinase CLK2 (3942 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CLK3 Tchem Dual specificity protein kinase CLK3 (2711 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CLK4 Tchem Dual specificity protein kinase CLK4 (4053 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
U2OS (164939 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
DYRK2 Tchem Dual-specificity tyrosine-phosphorylation regulated kinase 2 (2095 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
DYRK3 Tchem Dual-specificity tyrosine-phosphorylation regulated kinase 3 (1018 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
DYRK1B Tchem Dual specificity tyrosine-phosphorylation-regulated kinase 1B (2654 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
DYRK4 Tchem Dual specificity tyrosine-phosphorylation-regulated kinase 4 (692 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
BRD4 Tchem Bromodomain-containing protein 4 (13122 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CDK5 Tchem Cyclin-dependent kinase 5/CDK5 activator 1 (3697 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
TRIM24 Tchem Transcription intermediary factor 1-alpha (2087 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
BRPF1 Tchem Peregrin (2217 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
HEK-293T (167025 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Associated Targets(non-human)

Mapk1 MAP kinase ERK2 (650 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Hdac6 Histone deacetylase 6 (222 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Fgfr3 Fibroblast growth factor receptor 3 (21 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
HT-22 (3261 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Names and Identifiers

Pubchem Sid 488191483
Pubchem Sid Url https://pubchem.ncbi.nlm.nih.gov/substance/488191483
IUPAC Name 1-(4-methoxyphenyl)-2-methyl-3-nitroindol-6-ol
INCHI InChI=1S/C16H14N2O4/c1-10-16(18(20)21)14-8-5-12(19)9-15(14)17(10)11-3-6-13(22-2)7-4-11/h3-9,19H,1-2H3
InChIKey VVZNWYXIOADGSW-UHFFFAOYSA-N
Smiles CC1=C(C2=C(N1C3=CC=C(C=C3)OC)C=C(C=C2)O)[N+](=O)[O-]
Isomeric SMILES CC1=C(C2=C(N1C3=CC=C(C=C3)OC)C=C(C=C2)O)[N+](=O)[O-]
Molecular Weight 298.29
Reaxy-Rn 5825601
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=5825601&ln=

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

14 results found

Lot Number Certificate Type Date Item
E23061147 Certificate of Analysis Mar 30, 2023 I287101
E23061145 Certificate of Analysis Mar 30, 2023 I287101
E23061089 Certificate of Analysis Mar 30, 2023 I287101
E23061149 Certificate of Analysis Mar 30, 2023 I287101
E23061090 Certificate of Analysis Mar 30, 2023 I287101
E23061087 Certificate of Analysis Mar 30, 2023 I287101
E23061086 Certificate of Analysis Mar 30, 2023 I287101
E23061077 Certificate of Analysis Mar 30, 2023 I287101
E23061079 Certificate of Analysis Mar 30, 2023 I287101
E23061078 Certificate of Analysis Mar 30, 2023 I287101
E23061080 Certificate of Analysis Mar 30, 2023 I287101
E23061097 Certificate of Analysis Mar 30, 2023 I287101
E23061146 Certificate of Analysis Mar 30, 2023 I287101
E23061148 Certificate of Analysis Mar 30, 2023 I287101

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Chemical and Physical Properties

Solubility Solvent:DMSO, Max Conc. mg/mL: 29.83, Max Conc. mM: 100
Sensitivity Light Sensitive,Heat Sensitive
Melt Point(°C) 266 °C(dec.)
Molecular Weight 298.290 g/mol
XLogP3 3.500
Hydrogen Bond Donor Count 1
Hydrogen Bond Acceptor Count 4
Rotatable Bond Count 2
Exact Mass 298.095 Da
Monoisotopic Mass 298.095 Da
Topological Polar Surface Area 80.200 Ų
Heavy Atom Count 22
Formal Charge 0
Complexity 405.000
Isotope Atom Count 0
Defined Atom Stereocenter Count 0
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
The total count of all stereochemical bonds 0
Covalently-Bonded Unit Count 1

Solution Calculators

Reviews

Customer Reviews

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