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HT1042 , CAS No.23589-77-7, Inhibitor of proteasome 20S subunit beta 8

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HT1042 , CAS No.23589-77-7, Inhibitor of proteasome 20S subunit beta 8

COA

Grade & Purity:

Moligand™

Cas Number: 23589-77-7
PubChem CID: 325597

In stock

Item Number

H610868

Grouped product items
SKU	Size	Availability	Price	Qty
H610868-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$922.90
H610868-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$3,915.90

View related series

proteasome 20S subunit beta 8 Inhibitor (3)

Basic Description

Synonyms	5-(3-nitrophenyl)-1,3,4-oxathiazol-2-one \| HT1042 \| 23589-77-7 \| CHEMBL3265177 \| NSC294566 \| GTPL8649 \| SCHEMBL1781484 \| DTXSID10315430 \| BDBM50010993 \| AKOS040748540 \| NSC-294566 \| Q27077995
Specifications & Purity	Moligand™
Grade	Moligand™
Action Type	INHIBITOR
Mechanism of action	Inhibitor of proteasome 20S subunit beta 8

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Benzenoids
  - Class Benzene and substituted derivatives
    - Subclass Nitrobenzenes

Kingdom	Organic compounds
Superclass	Benzenoids
Class	Benzene and substituted derivatives
Subclass	Nitrobenzenes
Intermediate Tree Nodes	Not available
Direct Parent	Nitrobenzenes
Alternative Parents	Nitroaromatic compounds Heteroaromatic compounds Azoles Organic thiocarbonic acid derivatives Propargyl-type 1,3-dipolar organic compounds Oxacyclic compounds Organic oxoazanium compounds Azacyclic compounds Organooxygen compounds Organonitrogen compounds Organic salts Organic oxides Hydrocarbon derivatives Organic cations
Molecular Framework	Aromatic heteromonocyclic compounds
Substituents	Nitrobenzene - Nitroaromatic compound - Azole - Heteroaromatic compound - C-nitro compound - Thiocarbonic acid derivative - Organic nitro compound - Organic oxoazanium - Allyl-type 1,3-dipolar organic compound - Propargyl-type 1,3-dipolar organic compound - Organic 1,3-dipolar compound - Organoheterocyclic compound - Oxacycle - Azacycle - Organooxygen compound - Organic nitrogen compound - Organic oxygen compound - Organic oxide - Organic salt - Hydrocarbon derivative - Organonitrogen compound - Organic cation - Aromatic heteromonocyclic compound
Description	This compound belongs to the class of organic compounds known as nitrobenzenes. These are compounds containing a nitrobenzene moiety, which consists of a benzene ring with a carbon bearing a nitro group.
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Associated Targets(Human)

PSMB8 Tclin Proteasome subunit beta type-8 (2 Activities)

Discover Target: PSMB8

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

IUPAC Name	5-(3-nitrophenyl)-1,3,4-oxathiazol-2-one
INCHI	InChI=1S/C8H4N2O4S/c11-8-14-7(9-15-8)5-2-1-3-6(4-5)10(12)13/h1-4H
InChIKey	QBAZATRGWRVUFN-UHFFFAOYSA-N
Smiles	O=c1snc(o1)c1cccc(c1)[N+](=O)[O-]
Isomeric SMILES	C1=CC(=CC(=C1)[N+](=O)[O-])C2=NSC(=O)O2
PubChem CID	325597

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Chemical and Physical Properties

Molecular Weight	224.200 g/mol
XLogP3	2.000
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	1
Exact Mass	223.989 Da
Monoisotopic Mass	223.989 Da
Topological Polar Surface Area	110.000 Å²
Heavy Atom Count	15
Formal Charge	0
Complexity	325.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

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