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Hordenine - analytical standard,≥99%, high purity , CAS No.539-15-1

In stock
Item Number
H115723
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SKU Size
Availability
Price Qty
H115723-20mg
20mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$14.90
H115723-1g
1g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$547.90

Phenylethylamine alkaloid

Basic Description

Synonyms EINECS 208-710-4 | N,N-Dimethyltyramine | p-[2-(Dimethylamino)ethyl]phenol | Hordenine (sulfate) | BRD-K93631643-065-01-1 | K3489CA082 | P-(2-(DIMETHYLAMINO)ETHYL)PHENOL | HY-N0113 | H1351 | NCGC00160162-03 | DTXCID0026096 | HORDENINE [MI] | Hordenine | Q
Specifications & Purity analytical standard, ≥99%
Biochemical and Physiological Mechanisms Phenylethylamine alkaloid. Selective MAO-B substrate. Indirect adrenergic agent. Increases the release of stored noradrenaline. Inhibits melanogenesis by suppressing cAMP production. Shows positive ionotropic effects in vivo . Orally active.
Shipped In Normal
Grade analytical standard
Note Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
Superclass Benzenoids
Class Benzene and substituted derivatives
Subclass Phenethylamines
Intermediate Tree Nodes Not available
Direct Parent Phenethylamines
Alternative Parents Aralkylamines  1-hydroxy-2-unsubstituted benzenoids  Trialkylamines  Organopnictogen compounds  Organooxygen compounds  Hydrocarbon derivatives  
Molecular Framework Aromatic homomonocyclic compounds
Substituents Phenethylamine - 1-hydroxy-2-unsubstituted benzenoid - Aralkylamine - Phenol - Tertiary aliphatic amine - Tertiary amine - Organic nitrogen compound - Organic oxygen compound - Organopnictogen compound - Hydrocarbon derivative - Organooxygen compound - Organonitrogen compound - Amine - Aromatic homomonocyclic compound
Description This compound belongs to the class of organic compounds known as phenethylamines. These are compounds containing a phenethylamine moiety, which consists of a phenyl group substituted at the second position by an ethan-1-amine.
External Descriptors Tyramine derivatives

Associated Targets(Human)

A2780 (11979 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
GLS Tchem Glutaminase kidney isoform, mitochondrial (16997 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Associated Targets(non-human)

Hdac6 Histone deacetylase 6 (222 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Mus musculus (284745 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Names and Identifiers

IUPAC Name 4-[2-(dimethylamino)ethyl]phenol
INCHI InChI=1S/C10H15NO/c1-11(2)8-7-9-3-5-10(12)6-4-9/h3-6,12H,7-8H2,1-2H3
InChIKey KUBCEEMXQZUPDQ-UHFFFAOYSA-N
Smiles CN(C)CCC1=CC=C(C=C1)O
Isomeric SMILES CN(C)CCC1=CC=C(C=C1)O
WGK Germany 3
Molecular Weight 165.23
Beilstein 2207615
Reaxy-Rn 2207615
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2207615&ln=

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

2 results found

Lot Number Certificate Type Date Item
E2129199 Certificate of Analysis Mar 10, 2023 H115723
E2129198 Certificate of Analysis Mar 10, 2023 H115723

Chemical and Physical Properties

Molecular Weight 165.230 g/mol
XLogP3 2.100
Hydrogen Bond Donor Count 1
Hydrogen Bond Acceptor Count 2
Rotatable Bond Count 3
Exact Mass 165.115 Da
Monoisotopic Mass 165.115 Da
Topological Polar Surface Area 23.500 Ų
Heavy Atom Count 12
Formal Charge 0
Complexity 117.000
Isotope Atom Count 0
Defined Atom Stereocenter Count 0
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
The total count of all stereochemical bonds 0
Covalently-Bonded Unit Count 1

Citations of This Product

1. Jili Zou, Siran Wu, Bi Sheng, Jing An, Junhua Meng, Wang Xiong, Jiahan Tao, Wang Han, Lin Zhao, Hanlin Xu, Yonggang Chen.  (2023)  UPLC-Q-TOF-MS/MS analysis on the chemical composition of malts under different germination cycles and prepared with different processing methods.  FITOTERAPIA,  165  (105313). 
2. Yin Lujun, Shen Wang, Liu Jun-Sheng, Jia Ai-Qun.  (2022)  2-Hydroxymethyl-1-methyl-5-nitroimidazole, one siderophore inhibitor, occludes quorum sensing in Pseudomonas aeruginosa.  Frontiers in Cellular and Infection Microbiology,  12  (1302). 

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