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Honokiol - ≥98% (HPLC), high purity , CAS No.35354-74-6, Inhibitor of 5-LOX

34 Citations COA COA
In stock
Item Number
H111272
Grouped product items
SKU Size
Availability
 Price Qty
H111272-50mg
50mg
3
$9.90
H111272-200mg
200mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$13.90
H111272-250mg
250mg
3
$15.90
H111272-1g
1g
2
$19.90
H111272-5g
5g
4
$62.90
H111272-25g
25g
1
$213.90
Wish List
Bulk Order  SDS  DATASHEET  Specification Sheet

Anti-inflammatory and chemotherapeutic agent

View related series
5-LOX Inhibitor (7) Akt (180) Anti-infection (2803) Autophagy (1917) ERK (132) HCV (160) MAPK/ERK Pathway (546) PI3K/Akt/mTOR (765) Stem Cell/Wnt (1019) Virus (1811)

Basic Description

Synonyms 3',5-(5,5'-)Diallyl-[1,1'-biphenyl]-2,4'-(2,2'-)diol | BDBM50157304 | DTXSID30188845 | FT-0601638 | {1,1'-Biphenyl]-2,4'-diol, 3,5-di-2-propenyl- | FMLT BSASM H | HONOKIOL [WHO-DD] | MLS006011755 | 4-[2-hydroxy-5-(prop-2-en-1-yl)phenyl]-2-(prop-2-en-1-yl)
Specifications & Purity Moligand™, ≥98%(HPLC)
Biochemical and Physiological Mechanisms Potent scavenger of reactive oxygen species with antiangiogenic, antitumor and anti-inflammatory properties. Mechanisms of action include inhibition of ras signalling and activation of the mitochondrial transistion pore via cyclophilin D induction.
Storage Temp Store at 2-8°C
Shipped In
Wet ice
This product requires cold chain shipping. Ground and other economy services are not available.
Grade Moligand™
Action Type INHIBITOR
Mechanism of action Inhibitor of 5-LOX
Note Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
Superclass Benzenoids
Class Benzene and substituted derivatives
Subclass Biphenyls and derivatives
Intermediate Tree Nodes Not available
Direct Parent Biphenyls and derivatives
Alternative Parents 1-hydroxy-2-unsubstituted benzenoids  Organooxygen compounds  Hydrocarbon derivatives  
Molecular Framework Aromatic homomonocyclic compounds
Substituents Biphenyl - 1-hydroxy-2-unsubstituted benzenoid - Phenol - Organic oxygen compound - Hydrocarbon derivative - Organooxygen compound - Aromatic homomonocyclic compound
Description This compound belongs to the class of organic compounds known as biphenyls and derivatives. These are organic compounds containing to benzene rings linked together by a C-C bond.
External Descriptors Neolignans

Associated Targets(Human)

CNR1 Tclin Cannabinoid receptor 1 (1 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)
CNR2 Tchem Cannabinoid receptor 2 (1 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)
SIRT3 Tchem NAD-dependent protein deacetylase sirtuin-3, mitochondrial (1 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)
ALOX5 Tclin Arachidonate 5-lipoxygenase (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)
MGAM Tclin Maltase-glucoamylase (654 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ALOX5 Tclin Arachidonate 5-lipoxygenase (6568 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CNR1 Tclin Cannabinoid CB1 receptor (20913 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ACHE Tclin Acetylcholinesterase (18204 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
PTGS1 Tclin Cyclooxygenase-1 (9233 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
PTGS2 Tclin Cyclooxygenase-2 (13999 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
PPARG Tclin Peroxisome proliferator-activated receptor gamma (15191 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
PTH1R Tclin Parathyroid hormone receptor (47172 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CNR2 Tchem Cannabinoid CB2 receptor (16942 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
RXRA Tclin Retinoid X receptor alpha (3637 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
POLB Tchem DNA polymerase beta (23632 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
GAA Tclin Lysosomal alpha-glucosidase (35701 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
NR1H3 Tchem LXR-alpha (2891 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
SMPD1 Tchem Sphingomyelin phosphodiesterase (13561 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
GLP1R Tclin Glucagon-like peptide 1 receptor (111429 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ACE2 Tchem Angiotensin-converting enzyme 2 (190 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CCRF-CEM (65223 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
HT-29 (80576 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
K562 (73714 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
MCF7 (126967 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
NCI-H1975 (4994 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
NCI-H358 (882 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
PANC-1 (6144 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
PC-3 (62116 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Raji (5516 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
RKO (1376 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
SH-SY5Y (11521 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
SW480 (6023 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
A549 (127892 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
UACC-903 (393 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
HCT-116 (91556 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
HEK293 (82097 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
HepG2 (196354 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
NCI-H460 (60772 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
A2780 (11979 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
HUVEC (11049 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
PC-9 (1037 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
HeLa (62764 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
MDA-MB-231 (73002 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
SW-620 (52400 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
PBMC (10003 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
FEN1 Tchem Flap endonuclease 1 (12055 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
MGLL Tchem Monoglyceride lipase (1909 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
SIRT3 Tchem NAD-dependent deacetylase sirtuin 3 (1285 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
SLC5A7 Tchem High-affinity choline transporter (1462 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
HL (112 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
KDM4A Tchem Lysine-specific demethylase 4A (52245 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
APEX1 Tchem DNA-(apurinic or apyrimidinic site) lyase (38016 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
SNCA Tchem Alpha-synuclein (10960 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Associated Targets(non-human)

NA Neuraminidase (1107 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Ppard Peroxisome proliferator-activated receptor delta (358 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Hdac6 Histone deacetylase 6 (222 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Faah Anandamide amidohydrolase (3907 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Pseudomonas aeruginosa (123386 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Klebsiella pneumoniae (43867 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Micrococcus luteus (7463 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Staphylococcus aureus (210822 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Staphylococcus epidermidis (22802 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Acinetobacter baumannii (41033 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Escherichia coli (133304 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Streptococcus mutans (2687 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Streptococcus pyogenes (16140 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Bacillus subtilis (32866 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Enterococcus faecalis (29875 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Plasmodium falciparum (966862 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Cryptococcus neoformans (21258 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Candida albicans (78123 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Plasmodium berghei (192651 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Mus musculus (284745 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Rattus norvegicus (775804 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Human immunodeficiency virus 1 (70413 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Hepatitis C virus (23859 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Salmonella enterica (1497 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Stenotrophomonas maltophilia (1743 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
N2a (708 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Vero (26788 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
BV-2 (3710 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
SVR (53 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
BCHE Cholinesterase (8742 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Danio rerio (3092 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
dengue virus type 2 (2400 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Trichophyton mentagrophytes (4846 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
TGR Thioredoxin glutathione reductase (28579 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Mapt Microtubule-associated protein tau (6 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
PA Polymerase acidic protein (806 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Rorc Nuclear receptor ROR-gamma (89407 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
FTL Ferritin light chain (43324 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
NS1 Nonstructural protein 1 (33327 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
TIM10 Mitochondrial import inner membrane translocase subunit TIM10 (1435 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
HSP40, subfamily A, putative (505 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Gabrg2 GABA-A receptor; alpha-1/beta-2/gamma-2 (554 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
vpr Aberrant vpr protein (14595 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
SARS-CoV-2 (38078 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
SARS-CoV (424 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
I10 (29 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Names and Identifiers

Pubchem Sid 488184688
Pubchem Sid Url https://pubchem.ncbi.nlm.nih.gov/substance/488184688
IUPAC Name 2-(4-hydroxy-3-prop-2-enylphenyl)-4-prop-2-enylphenol
INCHI InChI=1S/C18H18O2/c1-3-5-13-7-9-18(20)16(11-13)14-8-10-17(19)15(12-14)6-4-2/h3-4,7-12,19-20H,1-2,5-6H2
InChIKey FVYXIJYOAGAUQK-UHFFFAOYSA-N
Smiles C=CCC1=CC(=C(C=C1)O)C2=CC(=C(C=C2)O)CC=C
Isomeric SMILES C=CCC1=CC(=C(C=C1)O)C2=CC(=C(C=C2)O)CC=C
WGK Germany 3
UN Number 3077
Molecular Weight 266.33
Reaxy-Rn 1982052
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1982052&ln=

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

17 results found

Lot Number Certificate Type Date Item
C2019087 Certificate of Analysis Jun 16, 2025 H111272
K2413301 Certificate of Analysis Nov 19, 2024 H111272
K2413302 Certificate of Analysis Nov 19, 2024 H111272
F1707005 Certificate of Analysis Aug 12, 2024 H111272
E2409036 Certificate of Analysis May 16, 2024 H111272
D2417338 Certificate of Analysis Apr 23, 2024 H111272
D2417328 Certificate of Analysis Apr 23, 2024 H111272
B2518290 Certificate of Analysis Apr 02, 2024 H111272
K2116361 Certificate of Analysis Aug 09, 2023 H111272
K2116360 Certificate of Analysis Aug 09, 2023 H111272
B2309655 Certificate of Analysis Feb 17, 2023 H111272
B2309684 Certificate of Analysis Feb 17, 2023 H111272
B2309867 Certificate of Analysis Feb 17, 2023 H111272
B2309818 Certificate of Analysis Feb 17, 2023 H111272
B2309608 Certificate of Analysis Feb 17, 2023 H111272
C2223350 Certificate of Analysis Apr 30, 2022 H111272
G1826038 Certificate of Analysis Apr 14, 2022 H111272

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Chemical and Physical Properties

Solubility Soluble in Methanol
Sensitivity Heat Sensitive
Melt Point(°C) 85°C
Molecular Weight 266.300 g/mol
XLogP3 5.000
Hydrogen Bond Donor Count 2
Hydrogen Bond Acceptor Count 2
Rotatable Bond Count 5
Exact Mass 266.131 Da
Monoisotopic Mass 266.131 Da
Topological Polar Surface Area 40.500 Ų
Heavy Atom Count 20
Formal Charge 0
Complexity 325.000
Isotope Atom Count 0
Defined Atom Stereocenter Count 0
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
The total count of all stereochemical bonds 0
Covalently-Bonded Unit Count 1

Citations of This Product

How to Cite Aladdin Scientific Products?
1. Fei Li, Chunyu Ye, Xiuli Wang, Xinting Li, Xiaoxia Wang.  (2023)  Honokiol ameliorates cigarette smoke-induced damage of airway epithelial cells via the SIRT3/SOD2 signalling pathway.  JOURNAL OF CELLULAR AND MOLECULAR MEDICINE,     
2. Chuanyi Gu, Chunru Wang, Wenjie Ma, Yunli Gao, Junyao Li, Qing Jin, Xiaochen Wu.  (2023)  Drug-Loaded Konjac Glucomannan/Metal–Organic Framework Composite Hydrogels as Antibacterial and Anti-Inflammatory Cell Scaffolds.  ACS Applied Materials & Interfaces,  15  (35): (41287–41298). 
3. Man Hu, Wen Jiang, Chen Ye, Ting Hu, Qingqing Yu, Moran Meng, Lijuan Sun, Jichao Liang, Yong Chen.  (2023)  Honokiol attenuates high glucose-induced peripheral neuropathy via inhibiting ferroptosis and activating AMPK/SIRT1/PGC-1ɑ pathway in Schwann cells.  PHYTOTHERAPY RESEARCH,     
4. Guoyu Wei, Wei Zhao, Anlong Hu, Mingjian Ren, Yunxiao Huang, Huayang Xu.  (2023)  Identification of a New Pathogenic fungi Causing Sorghum Leaf Spot Disease and Its Management Using Natural Product and Microorganisms.  Microorganisms,  11  (6): (1431). 
5. Yuan Hu, Miao Zhang, Bihan Liu, Yingying Tang, Zhuo Wang, Tao Wang, Jiaxin Zheng, Junjian Zhang.  (2023)  Honokiol prevents chronic cerebral hypoperfusion induced astrocyte A1 polarization to alleviate neurotoxicity by targeting SIRT3-STAT3 axis.  FREE RADICAL BIOLOGY AND MEDICINE,  202  (62). 
6. Meiying Ge, Guozheng Liang, Aijuan Gu.  (2023)  A facile strategy and mechanism to achieve biobased bismaleimide resins with high thermal-resistance and strength through copolymerizing with unique propargyl ether-functionalized allyl compound.  REACTIVE & FUNCTIONAL POLYMERS,  186  (105570). 
7. Weizhen Wang, Linan He, Zhuzhu Zhang, Wenzhi Li, Jia Chen, Tingting Chen, Youhua Long.  (2023)  Activity of the botanical compound thymol against kiwifruit rot caused by Fusarium tricinctum and the underlying mechanisms.  PEST MANAGEMENT SCIENCE,     
8. Wang Yixi, Ding Chuanyang, Ge Zhangjie, Li Zhipeng, Chen Lixin, Guo Xiaolong, Dong Genxi, Zhou Ping.  (2023)  A novel antibacterial and fluorescent coating composed of polydopamine and carbon dots on the surface of orthodontic brackets.  JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE,  34  (2): (1-12). 
9. Qingcong Wei, Ziming Jin, Weiwei Zhang, Yanfei Zhao, Yaxing Wang, Yixing Wei, Xing He, Guanglei Ma, Yuming Guo, Yuqin Jiang, Zhiguo Hu.  (2023)  Honokiol@PF127 crosslinked hyaluronate-based hydrogel for promoting wound healing by regulating macrophage polarization.  CARBOHYDRATE POLYMERS,  303  (120469). 
10. Junzhao Yuan, Xiaoqian Huang, Jianhong Gu, Yan Yuan, Zongping Liu, Hui Zou, Jianchun Bian.  (2023)  Honokiol reduces cadmium-induced oxidative injury and endosomal/lysosomal vacuolation via protecting mitochondrial function in quail (Coturnix japonica) liver tissues.  SCIENCE OF THE TOTAL ENVIRONMENT,  857  (159626). 
11. Yuyan Zhu, Lixia Zhang, Xiyuan Zhou.  (2022)  Honokiol Improves Acne-like Lesions in a Rabbit Ear Model by Alleviating Hyperkeratosis and Sebum Secretion.  Natural Product Communications,     
12. Bo Yu, Yiping Shen, Xuejie Zhang, Lijuan Ding, Zheng Meng, Xiaotong Wang, Meihua Han, Yifei Guo, Xiangtao Wang.  (2022)  Poly(methacrylate citric acid) as a Dual Functional Carrier for Tumor Therapy.  Pharmaceutics,  14  (9): (1765). 
13. Xin-Yuan Jiang, Zong-Yi Ren, Nian-Kun Zhang, Ke-Chen Yang, Gao-Xue Wang, Hai-Feng Jiang.  (2022)  Screening and evaluating honokiol from Magnolia officinalis against Nocardia seriolae infection in largemouth bass (Micropterus Salmoides).  JOURNAL OF FISH DISEASES,  45  (11): (1599-1607). 
14. Peng-Bo Duan, Ping-Ting Xiao, Xing Yang, Jin-Hua Hao, Kai Li, E-Hu Liu.  (2022)  Screening of hypoglycemic components in Platycladi Cacumen by phytochemical investigation, spectrum-effect relationship, and chemometric methods.  JOURNAL OF SEPARATION SCIENCE,  45  (14): (2591-2602). 
15. Hang Sun, Youjie Li, Xiao Wang, Xue Zhou, Simin Rong, Dongmin Liang, Guangbin Sun, Huizhen Cao, Hongfang Sun, Ranran Wang, Yunfei Yan, Shuyang Xie, Yunxiao Sun.  (2022)  TRIB2 regulates the expression of miR‑33a‑5p through the ERK/c‑Fos pathway to affect the imatinib resistance of chronic myeloid leukemia cells.  INTERNATIONAL JOURNAL OF ONCOLOGY,  60  (5): (1-14). 
16. Feixu Mo, Xianfeng Hu, Yi Ding, Rongyu Li, Youhua Long, Xiaomao Wu, Ming Li.  (2021)  Naturally produced magnolol can significantly damage the plasma membrane of Rhizoctonia solani.  PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY,  178  (104942). 
17. Jingwei Zhou, Yaoyao Hu, Peichun Chen, Hongwu Zhang.  (2020)  Preparation of restricted access monolithic tip via unidirectional freezing and atom transfer radical polymerization for directly extracting magnolol and honokiol from rat plasma followed by liquid chromatography analysis.  JOURNAL OF CHROMATOGRAPHY A,  1625  (461238). 
18. Qinglin He, Hua Yin, Jingjie Jiang, Yanfen Bai, Ning Chen, Shaowei Liu, Yibin Zhuang, Tao Liu.  (2017)  Fermentative Production of Phenolic Glucosides by Escherichia coli with an Engineered Glucosyltransferase from Rhodiola sachalinensis.  JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,  65  (23): (4691–4697). 
19. Jing Sun, Xueqi Fu, Ye Liu, Yongsen Wang, Bo Huo, Yidi Guo, Xuefeng Gao, Wannan Li, Xin Hu.  (2015)  Hypoglycemic effect and mechanism of honokiol on type 2 diabetic mice.  Drug Design Development and Therapy,  9  ( 6327–6342). 
20. Xu T, Meng JR, Cheng W, Liu JZ, Chu J, Zhang Q, Ma N, Bai LP, Guo Y..  (2022)  Discovery of honokiol thioethers containing 1,3,4-oxadiazole moieties as potential α-glucosidase and SARS-CoV-2 entry inhibitors..  Bioorg Med Chem,  67  (116838-116838). 
21. Haonan Sun, Yumin Liu, Xuedong Wang, Luan Shu.  (2024)  A network pharmacology-based method to explore the therapeutic effect of honokiol on diabetes with comorbid depression in mice.  EUROPEAN JOURNAL OF PHARMACOLOGY,  975  (176642). 
22. Zhang Chao, Wen Tingchi, Qiao Lijun, Guo Ming, Li Qihua, Lu Zhenghua, Zhu Zhenyuan, Lu Meiling.  (2024)  An environmentally safe formulation of plant derived fungicide: preparation and characterization of inclusion complex of honokiol and methyl-β-cyclodextrin.  JOURNAL OF INCLUSION PHENOMENA AND MACROCYCLIC CHEMISTRY,    (1-15). 
23. Shuo Xu, Shaorong Yan, Jun You, Xiaochen Wu.  (2024)  Antibacterial Micelles-Loaded Carboxymethyl Chitosan/Oxidized Konjac Glucomannan Composite Hydrogels for Enhanced Wound Repairing.  ACS Applied Materials & Interfaces,  16  (11): (13563-13572). 
24. Yilin Li, Yali Song, Na Gan, Lijuan Chen, Si Chen, Yi He, Tingting Zeng, Xinhui Wang, Wei Wang, Di Wu.  (2025)  Gliadin/Konjac glucomannan particle-stabilized Pickering emulsion for honokiol encapsulation with enhanced digestion benefits.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,  291  (139064). 
25. Miao Lurong, Yuan Ziqi, Zhang Shijia, Zhang Guangqin.  (2024)  Honokiol alleviates monosodium urate-induced gouty pain by inhibiting voltage-gated proton channels in mice.  INFLAMMOPHARMACOLOGY,    (1-13). 
26. Qiang Zhou, Meiyu Chang, Shuhan Guo, Yiming Zhang, Qiufang Qu, Qingnan Zhou, Zhiheng Li, Sanqiao Yao.  (2025)  Honokiol ameliorates silica-induced lung fibrosis by inhibiting macrophage pyroptosis via modulating cGAS/STING signaling.  INTERNATIONAL IMMUNOPHARMACOLOGY,  146  (113812). 
27. Weijuan Zou, Feng Gao, Zheying Meng, Xiaojun Cai, Wu Chen, Yuanyi Zheng, Tao Ying, Longchen Wang, Jianrong Wu.  (2024)  Lactic acid responsive sequential production of hydrogen peroxide and consumption of glutathione for enhanced ferroptosis tumor therapy.  JOURNAL OF COLLOID AND INTERFACE SCIENCE,  663  (787). 
28. Fei Yang, Bin Yang, Kaige Song, Yingjie Jin, Gaoxue Wang, Pengfei Li, Qing Yu, Fei Ling.  (2024)  Natural product honokiol exhibits antiviral effects against Micropterus salmoides rhabdovirus (MSRV) both in vitro and in vivo.  JOURNAL OF FISH DISEASES,  47  (4): (e13915). 
29. Guoyu Wei, Wei Zhao, Huayang Xu, Guangming Wang, Hualei Wang, Anlong Hu.  (2024)  Phytochemicals demonstrate potential fungicidal activity against Fusarium commune, a newly identified pathogenic fungus causing rhizome rot in Polygonatum cyrtonema (giant Chinese Solomon's seal).  JOURNAL OF PHYTOPATHOLOGY,  172  (2): (e13301). 
30. Chang Liu, Zhengjiang Cao, Li Li, Qingyin Li, Chunle Zhang, Yunbing Wang, Linhua Li, Ping Fu.  (2024)  Self-Assembled Pt/Honokiol Nanomicelles for the Treatment of Sepsis-Associated Acute Kidney Injury.  ACS Biomaterials Science & Engineering,  11  (1): (383-401). 
31. Ruige Yang, Xiangjing Fu, Jiangping Fan, Tingting Wang, Jian Song, Ting Xu, Yong Guo, Sai-Yang Zhang.  (2024)  Semisynthesis and biological evaluation of novel honokiol thioethers against colon cancer cells HCT116 via inhibiting the transcription and expression of YAP protein.  BIOORGANIC & MEDICINAL CHEMISTRY,  107  (117762). 
32. Zhen Qin, Qiang-qiang Chu, An-lan Ding, Chuan-Ying Li, Mao-yan Zhang.  (2024)  Sirtuin 3 ameliorates inflammatory bowel disease via inhibiting intestinal inflammation and oxidative stress.  JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION,  74  (3): (235-244). 
33. Zhen Lin, Ruyu Cao, Fan Nie, Lingling Ma, Jing Xu, Yuanqiang Guo.  (2025)  Synergistic chemoimmunotherapy in a green framework: pH-responsive natural plant polysaccharide-based nanoparticles.  Biomaterials Advances,  174  (214294). 
34. Xinkang Li, Zirui Chen, Lijun Tang, Jingjing Guo, Baoqiong Li.  (2024)  The Application of Multilinear Regression Model for Quantitative Analysis on the Basis of Excitation-Emission Matrix Spectra and the Release of a Free Graphical User Interface.  Symmetry-Basel,  16  (7): (922). 

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