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Homoeriodictyol 7-O-β-D-glucoside , CAS No.14982-11-7

In stock
Item Number
H647471
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H647471-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$290.90
H647471-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$740.90

Flavonoids Flavonones Phenols Polyphenols

Basic Description

Biochemical and Physiological Mechanisms Homoeriodictyol 7-O-β-D-glucoside is a natural platelet-activating factor (PAF) antagonist. Homoeriodictyol 7-O-β-D-glucoside inhibits human and rabbit platelet aggregation induced by PAF, with an IC 50 of 0.8 μM.
Storage Temp Store at -20°C
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Product Description

Homoeriodictyol 7-O-β-D-glucoside is a natural platelet-activating factor (PAF) antagonist. Homoeriodictyol 7-O-β-D-glucoside inhibits human and rabbit platelet aggregation induced by PAF, with an IC 50 of 0.8 μM

In Vitro

Homoeriodictyol 7-O-β-D-glucoside significantly inhibits human and rabbit platelet aggregation induced by PAF, but has no inhibitory effect on platelet aggregation induced by Adenosine diphosphate (ADP). MCE has not independently confirmed the accuracy of these methods. They are for reference only.

IC50& Target:platelet-activating factor

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
Superclass Phenylpropanoids and polyketides
Class Flavonoids
Subclass Flavonoid glycosides
Intermediate Tree Nodes Flavonoid O-glycosides
Direct Parent Flavonoid-7-O-glycosides
Alternative Parents 3'-O-methylated flavonoids  4'-hydroxyflavonoids  5-hydroxyflavonoids  Flavanones  Phenolic glycosides  Fatty acyl glycosides of mono- and disaccharides  Alkyl glycosides  Hexoses  Chromones  O-glycosyl compounds  Methoxyphenols  Phenoxy compounds  Anisoles  Aryl alkyl ketones  Methoxybenzenes  1-hydroxy-2-unsubstituted benzenoids  1-hydroxy-4-unsubstituted benzenoids  Alkyl aryl ethers  Oxanes  Vinylogous acids  Secondary alcohols  Polyols  Acetals  Oxacyclic compounds  Aldehydes  Primary alcohols  Organic oxides  Hydrocarbon derivatives  
Molecular Framework Aromatic heteropolycyclic compounds
Substituents Flavonoid-7-o-glycoside - 3p-methoxyflavonoid-skeleton - 4'-hydroxyflavonoid - 5-hydroxyflavonoid - Flavanone - Hydroxyflavonoid - Flavan - Phenolic glycoside - Fatty acyl glycoside - Fatty acyl glycoside of mono- or disaccharide - Alkyl glycoside - Hexose monosaccharide - Chromone - Glycosyl compound - O-glycosyl compound - Chromane - Benzopyran - Methoxyphenol - 1-benzopyran - Anisole - Phenol ether - Aryl ketone - Aryl alkyl ketone - Methoxybenzene - Phenoxy compound - Phenol - 1-hydroxy-2-unsubstituted benzenoid - Alkyl aryl ether - 1-hydroxy-4-unsubstituted benzenoid - Oxane - Benzenoid - Monosaccharide - Monocyclic benzene moiety - Fatty acyl - Vinylogous acid - Ketone - Secondary alcohol - Acetal - Oxacycle - Organoheterocyclic compound - Polyol - Ether - Organooxygen compound - Organic oxygen compound - Aldehyde - Alcohol - Primary alcohol - Organic oxide - Hydrocarbon derivative - Aromatic heteropolycyclic compound
Description This compound belongs to the class of organic compounds known as flavonoid-7-o-glycosides. These are phenolic compounds containing a flavonoid moiety which is O-glycosidically linked to carbohydrate moiety at the C7-position.
External Descriptors Not available

Associated Targets(non-human)

RAW264.7 (28094 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Names and Identifiers

IUPAC Name (2S)-5-hydroxy-2-(4-hydroxy-3-methoxyphenyl)-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2,3-dihydrochromen-4-one
INCHI InChI=1S/C22H24O11/c1-30-15-4-9(2-3-11(15)24)14-7-13(26)18-12(25)5-10(6-16(18)32-14)31-22-21(29)20(28)19(27)17(8-23)33-22/h2-6,14,17,19-25,27-29H,7-8H2,1H3/t14-,17+,19+,20-,21+,22+/m0/s1
InChIKey KZQCCKUDYVSOLC-YMTXFHFDSA-N
Smiles COC1=C(C=CC(=C1)C2CC(=O)C3=C(C=C(C=C3O2)OC4C(C(C(C(O4)CO)O)O)O)O)O
Isomeric SMILES COC1=C(C=CC(=C1)[C@@H]2CC(=O)C3=C(C=C(C=C3O2)O[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O)O)O
PubChem CID 21629877
Molecular Weight 464.42

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Chemical and Physical Properties

Molecular Weight 464.400 g/mol
XLogP3 0.600
Hydrogen Bond Donor Count 6
Hydrogen Bond Acceptor Count 11
Rotatable Bond Count 5
Exact Mass 464.132 Da
Monoisotopic Mass 464.132 Da
Topological Polar Surface Area 175.000 Ų
Heavy Atom Count 33
Formal Charge 0
Complexity 677.000
Isotope Atom Count 0
Defined Atom Stereocenter Count 6
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
The total count of all stereochemical bonds 0
Covalently-Bonded Unit Count 1

Solution Calculators

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