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hexamethonium , CAS No.60-26-4, Channel blocker of nicotinic acetylcholine receptor α2 subunit;Channel blocker of nicotinic acetylcholine receptor α3 subunit;Channel blocker of nicotinic acetylcholine receptor α4 subunit;Channel blocker of nicotinic acetylcholine receptor α6 subunit

COA

Grade & Purity:

Moligand™

Cas Number: 60-26-4
PubChem CID: 3604

In stock

Item Number

H610823

Grouped product items
SKU	Size	Availability	Price	Qty
H610823-25μg	25μg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,191.90
H610823-100μg	100μg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$3,334.90

View related series

nicotinic acetylcholine receptor α2 subunit Channel blocker (2) nicotinic acetylcholine receptor α3 subunit Channel blocker (4) nicotinic acetylcholine receptor α4 subunit Channel blocker (4) nicotinic acetylcholine receptor α6 subunit Channel blocker (2)

Basic Description

Synonyms	Prestwick1_000038 \| Prestwick3_000038 \| N,N,N,N',N',N'-hexamethylhexane-1,6-diaminium \| .ALPHA.,.OMEGA.-BIS(TRIMETHYLAMMONIUM)HEXANE \| Ammonium, hexamethylenebis(trimethyl- \| CCG-204702 \| hexamethylenebis(trimethylammonium) \| KBio2_004707 \| Lopac0_000622
Specifications & Purity	Moligand™
Grade	Moligand™
Action Type	CHANNEL BLOCKER
Mechanism of action	Channel blocker of nicotinic acetylcholine receptor α2 subunit;Channel blocker of nicotinic acetylcholine receptor α3 subunit;Channel blocker of nicotinic acetylcholine receptor α4 subunit;Channel blocker of nicotinic acetylcholine receptor α6 subunit

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Organic nitrogen compounds
  - Class Organonitrogen compounds
    - Subclass Quaternary ammonium salts

Kingdom	Organic compounds
Superclass	Organic nitrogen compounds
Class	Organonitrogen compounds
Subclass	Quaternary ammonium salts
Intermediate Tree Nodes	Not available
Direct Parent	Hexamethonium compounds
Alternative Parents	Tetraalkylammonium salts Organopnictogen compounds Organic salts Hydrocarbon derivatives Amines Organic cations
Molecular Framework	Aliphatic acyclic compounds
Substituents	Hexamethonium - Tetraalkylammonium salt - Organopnictogen compound - Hydrocarbon derivative - Organic salt - Amine - Organic cation - Aliphatic acyclic compound
Description	This compound belongs to the class of organic compounds known as hexamethonium compounds. These are organic compounds containing a N,N,N,N',N',N'-hexamethylhexane-1,6-diaminium moiety.
External Descriptors	quaternary ammonium salt
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Associated Targets(Human)

CHRNA6 Tchem Neuronal acetylcholine receptor subunit alpha-6 (1 Activities)

Discover Target: CHRNA6

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CHRNA3 Tclin Neuronal acetylcholine receptor subunit alpha-3 (0 Activities)

Discover Target: CHRNA3

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CHRNA4 Tclin Neuronal acetylcholine receptor subunit alpha-4 (1 Activities)

Discover Target: CHRNA4

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CHRNA2 Tchem Neuronal acetylcholine receptor subunit alpha-2 (0 Activities)

Discover Target: CHRNA2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

IUPAC Name	trimethyl[6-(trimethylazaniumyl)hexyl]azanium
INCHI	InChI=1S/C12H30N2/c1-13(2,3)11-9-7-8-10-12-14(4,5)6/h7-12H2,1-6H3/q+2
InChIKey	VZJFGSRCJCXDSG-UHFFFAOYSA-N
Smiles	C[N+](CCCCCC[N+](C)(C)C)(C)C
Isomeric SMILES	C[N+](C)(C)CCCCCC[N+](C)(C)C
PubChem CID	3604

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Chemical and Physical Properties

Molecular Weight	202.380 g/mol
XLogP3	1.800
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	0
Rotatable Bond Count	7
Exact Mass	202.241 Da
Monoisotopic Mass	202.241 Da
Topological Polar Surface Area	0.000 Å²
Heavy Atom Count	14
Formal Charge	2
Complexity	121.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

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