Basic Description

Synonyms	BCP22497 \| Heptafluorobutyric anhydride \| HEPTAFLUOROBUTYRYL ANHYDRIDE \| Heptafluorobutanoic anhydride \| J-521428 \| Butanoic acid, 2,2,3,3,4,4,4-heptafluoro-, 1,1'-anhydride \| GC10217 \| 1,1,2,2,3,3,3-Heptafluorobutanoic anhydride # \| DTXSID10861881 \| UNII
Specifications & Purity	≥97%
Shipped In	Normal
Product Description	Derivatization reagent used in a GC-MS analysis of stereoisomer content of synthetic peptides. GC derivatizing agent used to prepare volatile derivatives of amino acids and other biologically active compounds.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Organohalogen compounds
  - Class Alkyl halides
    - Subclass Alkyl fluorides

Kingdom	Organic compounds
Superclass	Organohalogen compounds
Class	Alkyl halides
Subclass	Alkyl fluorides
Intermediate Tree Nodes	Not available
Direct Parent	Perfluoroalkyl carboxylic acid and derivatives
Alternative Parents	Dicarboxylic acids and derivatives Carboxylic acid anhydrides Alpha-halocarboxylic acid derivatives Organofluorides Organic oxides Hydrocarbon derivatives Carbonyl compounds
Molecular Framework	Aliphatic acyclic compounds
Substituents	Perfluoroalkyl carboxylic acid or derivatives - Dicarboxylic acid or derivatives - Carboxylic acid anhydride - Alpha-halocarboxylic acid or derivatives - Alpha-halocarboxylic acid derivative - Carboxylic acid derivative - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Organofluoride - Carbonyl group - Aliphatic acyclic compound
Description	This compound belongs to the class of organic compounds known as perfluoroalkyl carboxylic acid and derivatives. These are organic compounds containing an alkyl chain attached to the C-alpha of a carboxylic acid group (or a derivative thereof), where all hydrogens of the alkyl chain are replaced by fluorine atoms.
External Descriptors	organofluorine compound - acyclic carboxylic anhydride
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Names and Identifiers

Pubchem Sid	504754179
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/504754179
IUPAC Name	2,2,3,3,4,4,4-heptafluorobutanoyl 2,2,3,3,4,4,4-heptafluorobutanoate
INCHI	InChI=1S/C8F14O3/c9-3(10,5(13,14)7(17,18)19)1(23)25-2(24)4(11,12)6(15,16)8(20,21)22
InChIKey	UFFSXJKVKBQEHC-UHFFFAOYSA-N
Smiles	C(=O)(C(C(C(F)(F)F)(F)F)(F)F)OC(=O)C(C(C(F)(F)F)(F)F)(F)F
Isomeric SMILES	C(=O)(C(C(C(F)(F)F)(F)F)(F)F)OC(=O)C(C(C(F)(F)F)(F)F)(F)F
WGK Germany	3
Molecular Weight	410.06
Beilstein	856036
Reaxy-Rn	856036
Reaxys-RN_link_address	https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=856036&ln=

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

24 results found

Lot Number	Certificate Type	Date	Item
F2320283	Certificate of Analysis	Apr 18, 2025	H111065
C2526497	Certificate of Analysis	Mar 19, 2025	H111065
C2526499	Certificate of Analysis	Mar 19, 2025	H111065
C2526496	Certificate of Analysis	Mar 19, 2025	H111065
C2526500	Certificate of Analysis	Mar 19, 2025	H111065
D2502545	Certificate of Analysis	Mar 19, 2025	H111065
F2320288	Certificate of Analysis	Mar 03, 2025	H111065
F2320274	Certificate of Analysis	Mar 03, 2025	H111065
F2320287	Certificate of Analysis	Mar 03, 2025	H111065
A2513491	Certificate of Analysis	Jan 09, 2025	H111065
A2513494	Certificate of Analysis	Jan 09, 2025	H111065
A2513492	Certificate of Analysis	Jan 09, 2025	H111065
A2513493	Certificate of Analysis	Jan 09, 2025	H111065
B2302403	Certificate of Analysis	Nov 07, 2024	H111065
D2417340	Certificate of Analysis	Mar 25, 2024	H111065
D2417333	Certificate of Analysis	Mar 22, 2024	H111065
L2106562	Certificate of Analysis	Sep 20, 2023	H111065
L2106493	Certificate of Analysis	Sep 20, 2023	H111065
L2106563	Certificate of Analysis	Sep 20, 2023	H111065
I2413011	Certificate of Analysis	Jun 09, 2023	H111065
F2320285	Certificate of Analysis	Jun 09, 2023	H111065
K2009331	Certificate of Analysis	Sep 15, 2022	H111065
E2220213	Certificate of Analysis	May 28, 2022	H111065
K2221119	Certificate of Analysis	Nov 23, 2021	H111065

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Chemical and Physical Properties

Sensitivity	Moisture sensitive.
Refractive Index	1.287
Boil Point(°C)	108-111°C
Melt Point(°C)	-43°C
Molecular Weight	410.060 g/mol
XLogP3	4.800
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	17
Rotatable Bond Count	6
Exact Mass	409.962 Da
Monoisotopic Mass	409.962 Da
Topological Polar Surface Area	43.400 Å²
Heavy Atom Count	25
Formal Charge	0
Complexity	493.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

Citations of This Product

How to Cite Aladdin Scientific Products?

1. Suleixin Yang, Yi Wu, Wenzhao Zhong, Ruie Chen, Meilin Wang, Meiwan Chen. (2023) GSH/Ph Dual Activatable Crosslinked And Fluorinated Pei for Cancer Gene Therapy Through Endogenous Iron De-Hijacking And in Situ Ros Amplification. ADVANCED MATERIALS, (2304098).
2. Shengnan Ma, Lei Song, Yueyue Bai, Shihao Wang, Jiao Wang, Haohao Zhang, Fazhan Wang, Yiyan He, Chuntao Tian, Guijun Qin. (2023) Improved intracellular delivery of exosomes by surface modification with fluorinated peptide dendrimers for promoting angiogenesis and migration of HUVECs. RSC Advances, 13 (17): (11269-11277).
3. Peng Hua, Donglin Yang, Ruie Chen, Peiqi Qiu, Meiwan Chen. (2022) ROS responsive polyethylenimine-based fluorinated polymers for enhanced transfection efficiency and lower cytotoxicity. Bosnian Journal of Basic Medical Sciences, 22 (4): ( 593–607).
4. Suleixin Yang, Ka Hong Wong, Peng Hua, Chengwei He, Hua Yu, Dan Shao, Zhi Shi, Meiwan Chen. (2022) ROS-responsive fluorinated polyethyleneimine vector to co-deliver shMTHFD2 and shGPX4 plasmids induces ferroptosis and apoptosis for cancer therapy. Acta Biomaterialia, 140 (492).
5. Fangyin Zhu, Liang Xu, Xudong Li, Ziying Li, Jun Wang, Haijun Chen, Xiumei Li, Yu Gao. (2021) Co-delivery of gefitinib and hematoporphyrin by aptamer-modified fluorinated dendrimer for hypoxia alleviation and enhanced synergistic chemo-photodynamic therapy of NSCLC. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 167 (106004).
6. Hongyuan Yuan, Yong Yang, Wei Xue, Zonghua Liu. (2019) Fluorinated Redox-Responsive Poly(amidoamine) as a Vaccine Delivery System for Antitumor Immunotherapy. ACS Biomaterials Science & Engineering, 5 (2): (644–653).
7. Ma Shengnan, Zhou Jie, Wali Aisha Roshan Mohamed, He Yiyan, Xu Xianghui, Tang James Zhenggui, Gu Zhongwei. (2015) Self-assembly of pH-sensitive fluorinated peptide dendron functionalized dextran nanoparticles for on-demand intracellular drug delivery. JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE, 26 (8): (1-13).
8. Qiurong Deng,Xudong Li,Lipeng Zhu,Hua He,Donglai Chen,Yongbing Chen,Lichen Yin. (2017-05-18) Serum-resistant, reactive oxygen species (ROS)-potentiated gene delivery in cancer cells mediated by fluorinated, diselenide-crosslinked polyplexes.. Biomaterials science, 5 ((6)): (1174-1182).
9. Peng Hua, Ruifeng Liang, Suleixin Yang, Yanbei Tu, Meiwan Chen. (2024) Microneedle-assisted dual delivery of PUMA gene and celastrol for synergistic therapy of rheumatoid arthritis through restoring synovial homeostasis. Bioactive Materials, 36 (83).

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SKU	Size	Availability	Price
H111065-1g	1g	3	$9.90
H111065-5g	5g	3	$35.90
H111065-10g	10g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$54.90
H111065-25g	25g	1	$121.90
H111065-100g	100g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$438.90

Heptafluorobutyric anhydride - 97%, high purity , CAS No.336-59-4