Skip to the beginning of the images gallery

Hematoporphyrin monomethyl Ether - ≥95%, high purity , CAS No.148471-91-4

1 Citations

COA

Grade & Purity:

≥95%

Cas Number: 148471-91-4
Molecular Weight: 612.72
PubChem CID: 11570804
PubChem SID: 488197595

In stock

Item Number

H302937

Grouped product items
SKU	Size	Availability	Price
H302937-5mg	5mg	3	$267.90
H302937-10mg	10mg	1	$434.90
H302937-25mg	25mg	1	$867.90
H302937-50mg	50mg	1	$1,400.90
H302937-100mg	100mg	1	$2,234.90

View related series

Apoptosis (4276)

Basic Description

Synonyms	HMME
Specifications & Purity	≥95%
Storage Temp	Store at 2-8°C,Protected from light,Desiccated
Shipped In	Wet ice This product requires cold chain shipping. Ground and other economy services are not available.
Product Description	Product Describtion: Hematoporphyrin monomethyl ether, second generation of porphyrin-related photosensitizer, is characterized by its single form, high yield of singlet oxygen, high selectivity, and low toxicity, which has been widely used in the diagnosis and treatment of various tumors, including lung cancer, bladder cancer, and nevus flammeus and brain glioma Product Application: Hematoporphyrin monomethyl ether (HMME) is a novel and promising porphyrin-related photosensitizer for photodynamic therapy (PDT). HMME-PDT can induce cell deaththrough both necrosis and apoptosis in HeLa cells. ROS, such as singlet oxygen and hydroxyl radical, generated in HeLa cells play a decisive role in HMME-PDT-induced cell death.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Organoheterocyclic compounds
  - Class Tetrapyrroles and derivatives
    - Subclass Porphyrins

Kingdom	Organic compounds
Superclass	Organoheterocyclic compounds
Class	Tetrapyrroles and derivatives
Subclass	Porphyrins
Intermediate Tree Nodes	Not available
Direct Parent	Porphyrins
Alternative Parents	Substituted pyrroles Dicarboxylic acids and derivatives Heteroaromatic compounds Secondary alcohols Dialkyl ethers Carboxylic acids Azacyclic compounds Organonitrogen compounds Organic oxides Hydrocarbon derivatives Carbonyl compounds Aromatic alcohols
Molecular Framework	Aromatic heteropolycyclic compounds
Substituents	Porphyrin - Dicarboxylic acid or derivatives - Substituted pyrrole - Pyrrole - Heteroaromatic compound - Secondary alcohol - Carboxylic acid derivative - Carboxylic acid - Dialkyl ether - Ether - Azacycle - Organooxygen compound - Organonitrogen compound - Alcohol - Organic nitrogen compound - Carbonyl group - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Aromatic alcohol - Aromatic heteropolycyclic compound
Description	This compound belongs to the class of organic compounds known as porphyrins. These are compounds containing a fundamental skeleton of four pyrrole nuclei united through the alpha-positions by four methine groups to form a macrocyclic structure.
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Associated Targets(Human)

MCF7 (126967 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HepG2 (196354 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

MDA-MB-231 (73002 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

Mus musculus (284745 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

Pubchem Sid	488197595
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/488197595
IUPAC Name	3-[18-(2-carboxyethyl)-8-(1-hydroxyethyl)-13-(1-methoxyethyl)-3,7,12,17-tetramethyl-22,23-dihydroporphyrin-2-yl]propanoic acid
INCHI	InChI=1S/C35H40N4O6/c1-16-22(8-10-32(41)42)28-15-29-23(9-11-33(43)44)17(2)25(37-29)13-31-35(21(6)45-7)19(4)27(39-31)14-30-34(20(5)40)18(3)26(38-30)12-24(16)36-28/h12-15,20-21,38-40H,8-11H2,1-7H3,(H,41,42)(H,43,44)
InChIKey	NDYWLKUTUDKOAS-UHFFFAOYSA-N
Smiles	CC1=C(C2=CC3=NC(=CC4=NC(=CC5=C(C(=C(N5)C=C1N2)C(C)O)C)C(=C4CCC(=O)O)C)C(=C3C)CCC(=O)O)C(C)OC
Isomeric SMILES	CC1=C(C2=CC3=NC(=CC4=NC(=CC5=C(C(=C(N5)C=C1N2)C(C)O)C)C(=C4CCC(=O)O)C)C(=C3C)CCC(=O)O)C(C)OC
PubChem CID	11570804
Molecular Weight	612.72

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

11 results found

Lot Number	Certificate Type	Date	Item
E2315297	Certificate of Analysis	Mar 31, 2023	H302937
E2315308	Certificate of Analysis	Mar 31, 2023	H302937
E2315304	Certificate of Analysis	Mar 31, 2023	H302937
E2315307	Certificate of Analysis	Mar 31, 2023	H302937
K2405024	Certificate of Analysis	Mar 31, 2023	H302937
E2315311	Certificate of Analysis	Mar 31, 2023	H302937
E2315306	Certificate of Analysis	Mar 31, 2023	H302937
E2315302	Certificate of Analysis	Mar 31, 2023	H302937
E2315309	Certificate of Analysis	Mar 31, 2023	H302937
E2315312	Certificate of Analysis	Mar 31, 2023	H302937
E2315315	Certificate of Analysis	Mar 31, 2023	H302937

Show more⌵

Chemical and Physical Properties

Solubility	souble in DMSO
Sensitivity	Sensitive to light
Boil Point(°C)	1123.6±65.0 °C

Alternative Products

Citations of This Product

How to Cite Aladdin Scientific Products?

1. Ling-Kun Zhang, Shiwei Du, Xiaozhen Wang, Yuxuan Jiao, Liang Yin, Yi Zhang, Yan-Qing Guan. (2019) Bacterial cellulose based composites enhanced transdermal drug targeting for breast cancer treatment. CHEMICAL ENGINEERING JOURNAL, 370 (749).

Solution Calculators

Molarity Calculator

Determine the necessary mass, volume, or concentration for preparing a solution.

Mass

Concentration

Volume

M. Wt*

g/mol

*When preparing stock solutions, always use the batch-specific molecular weight of the product found on the vial label and the Certificate of Analysis (available online).

Dilution Calculator

Determine the dilution needed to prepare a stock solution.

Concentration 1 (C1)

Volume 1 (V1)

Concentration 2 (C2)

Volume 2 (V2)

Reconstitution Calculator

The reconstitution calculator enables you to quickly determine the volume of a reagent needed to reconstitute your vial. Just enter the mass of the reagent and the target concentration, and the calculator will do the rest.

Volume (to add to vial)

Mass (in vial)

Desired Reconstitution Concentration

Hematoporphyrin monomethyl Ether - ≥95%, high purity , CAS No.148471-91-4

Basic Description

Taxonomic Classification

Associated Targets(Human)

Associated Targets(non-human)

Mechanisms of Action

Names and Identifiers

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

Show more⌵

Chemical and Physical Properties

Alternative Products

Citations of This Product

Solution Calculators

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

Reviews

Customer Reviews