Skip to the beginning of the images gallery

GW 1929 hydrochloride - ≥98%(HPLC), high purity , CAS No.1217466-21-1

COA

Grade & Purity:

≥98%(HPLC)

Cas Number: 1217466-21-1
Molecular Weight: 532.03
PubChem CID: 56972174

In stock

Item Number

G286659

Grouped product items
SKU	Size	Availability	Price
G286659-1mg	1mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$19.90
G286659-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$99.90
G286659-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$219.90
G286659-50mg	50mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$399.90

Selective PPARγ agonist

View related series

Cell Cycle (2830) Cell Cycle/DNA Damage (2602) Lipid metabolism (1912) PPAR (155) PPARγ Agonists (2) Vitamin D Related/Nuclear Receptor (907)

Basic Description

Synonyms	N-(2-Benzoylphenyl)-O-[2-(methyl-2-pyridinylamino)ethyl]-L-tyrosine hydrochloride
Specifications & Purity	≥98%(HPLC)
Biochemical and Physiological Mechanisms	Highly selective orally active peroxisome proliferator-activated receptor (PPAR)γagonist (pEC50values are 8.05, < 4 and < 4 for human PPARγ, PPARαand PPARδreceptors respectively). Decreases glucose, fatty acid and triglyceride levels following oral admini
Storage Temp	Store at -20°C,Desiccated
Shipped In	Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available.
Product Description	Highly selective orally active peroxisome proliferator-activated receptor (PPAR)γ agonist (pEC50 values are 8.05, < 4 and < 4 for human PPARγ, PPARα and PPARδ receptors respectively). Decreases glucose, fatty acid and triglyceride levels following oral administration in vivo.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Organic acids and derivatives
  - Class Carboxylic acids and derivatives
    - Subclass Amino acids, peptides, and analogues
      - Level5 Amino acids and derivatives
        Level6 Alpha amino acids and derivatives
        Level7 Phenylalanine and derivatives

Kingdom	Organic compounds
Superclass	Organic acids and derivatives
Class	Carboxylic acids and derivatives
Subclass	Amino acids, peptides, and analogues
Intermediate Tree Nodes	Amino acids and derivatives - Alpha amino acids and derivatives
Direct Parent	Phenylalanine and derivatives
Alternative Parents	Benzophenones Aryl-phenylketones Diphenylmethanes Phenylpropanoic acids Amphetamines and derivatives L-alpha-amino acids Benzoyl derivatives Aniline and substituted anilines Dialkylarylamines Phenylalkylamines Phenoxy compounds Phenol ethers Aminopyridines and derivatives Secondary alkylarylamines Alkyl aryl ethers Imidolactams Heteroaromatic compounds Vinylogous amides Amino acids Monocarboxylic acids and derivatives Carboxylic acids Azacyclic compounds Hydrocarbon derivatives Organic oxides Hydrochlorides
Molecular Framework	Aromatic heteromonocyclic compounds
Substituents	Phenylalanine or derivatives - Benzophenone - Diphenylmethane - Aryl-phenylketone - 3-phenylpropanoic-acid - Alpha-amino acid - Amphetamine or derivatives - L-alpha-amino acid - Phenol ether - Aryl ketone - Phenoxy compound - Dialkylarylamine - Benzoyl - Aniline or substituted anilines - Phenylalkylamine - Aralkylamine - Alkyl aryl ether - Secondary aliphatic/aromatic amine - Aminopyridine - Pyridine - Benzenoid - Imidolactam - Monocyclic benzene moiety - Vinylogous amide - Heteroaromatic compound - Amino acid - Ketone - Tertiary amine - Monocarboxylic acid or derivatives - Ether - Organoheterocyclic compound - Carboxylic acid - Azacycle - Secondary amine - Organonitrogen compound - Organic oxygen compound - Carbonyl group - Hydrochloride - Hydrocarbon derivative - Organic nitrogen compound - Organic oxide - Organooxygen compound - Amine - Aromatic heteromonocyclic compound
Description	This compound belongs to the class of organic compounds known as phenylalanine and derivatives. These are compounds containing phenylalanine or a derivative thereof resulting from reaction of phenylalanine at the amino group or the carboxy group, or from the replacement of any hydrogen of glycine by a heteroatom.
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Associated Targets(Human)

PPARG Tclin Peroxisome proliferator-activated receptor gamma (1 Activities)

Discover Target: PPARG

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

IUPAC Name	(2S)-2-(2-benzoylanilino)-3-[4-[2-[methyl(pyridin-2-yl)amino]ethoxy]phenyl]propanoic acid;hydrochloride
INCHI	InChI=1S/C30H29N3O4.ClH/c1-33(28-13-7-8-18-31-28)19-20-37-24-16-14-22(15-17-24)21-27(30(35)36)32-26-12-6-5-11-25(26)29(34)23-9-3-2-4-10-23;/h2-18,27,32H,19-21H2,1H3,(H,35,36);1H/t27-;/m0./s1
InChIKey	KXNKIKXTGRMLEY-YCBFMBTMSA-N
Smiles	CN(CCOC1=CC=C(C=C1)CC(C(=O)O)NC2=CC=CC=C2C(=O)C3=CC=CC=C3)C4=CC=CC=N4.Cl
Isomeric SMILES	CN(CCOC1=CC=C(C=C1)C[C@@H](C(=O)O)NC2=CC=CC=C2C(=O)C3=CC=CC=C3)C4=CC=CC=N4.Cl
Alternate CAS	196808-24-9
PubChem CID	56972174
Molecular Weight	532.03

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Chemical and Physical Properties

Solubility	Solvent:ethanol, Max Conc. mg/mL: 49.56, Max Conc. mM: 100 with gentle warming; Solvent:water, Max Conc. mg/mL: 26.6, Max Conc. mM: 50

Solution Calculators

Molarity Calculator

Determine the necessary mass, volume, or concentration for preparing a solution.

Mass

Concentration

Volume

M. Wt*

g/mol

*When preparing stock solutions, always use the batch-specific molecular weight of the product found on the vial label and the Certificate of Analysis (available online).

Dilution Calculator

Determine the dilution needed to prepare a stock solution.

Concentration 1 (C1)

Volume 1 (V1)

Concentration 2 (C2)

Volume 2 (V2)

Reconstitution Calculator

The reconstitution calculator enables you to quickly determine the volume of a reagent needed to reconstitute your vial. Just enter the mass of the reagent and the target concentration, and the calculator will do the rest.

Volume (to add to vial)

Mass (in vial)

Desired Reconstitution Concentration