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Guaifenesin - 10mM in DMSO, high purity , CAS No.93-14-1(DMSO)

In stock
Item Number
G407746
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SKU Size
Availability
Price Qty
G407746-1ml
1ml
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$347.90

Expectorant agent

View related series
Compound libraries (12325)

Basic Description

Synonyms 3-​(2-​methoxyphenoxy)​-1,​2-​propanediol
Specifications & Purity Moligand™, 10mM in DMSO
Biochemical and Physiological Mechanisms Guaifenesin is an expectorant used to relieve chest congestion.
Storage Temp Store at -80°C
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Grade Moligand™
Product Description

Information

Guaifenesin is an expectorant used to relieve chest congestion.
In vitro


In vivo

Guaifenesin (200 mg/kg, intravenously) combined with ketamine (50 mg/kg, intramuscularly) produces effective and safe surgical anesthesia for over 30 minutes in New Zealand white rabbits. Guaifenesin (200 mg/kg, intravenously) combined with ketamine (50 mg/kg, intramuscularly) mildly depresses respiratory rate but heart rate and arterial blood pressure are not significantly affected. Guaifenesin (200 mg/kg, intravenously) is combined with sodium pentobarbital (20 mg/kg, intravenously) to produce surgical anesthesia for a period of more than 30 minutes. Guaifenesin (50 mg/mL) combined Xylazine (0.1 mg/mL) and Ketamine (1.0 mg/mL) results in excellent anesthetic induction and maintenance with cardiopulmonary alterations similar to those associated with isoflurane in mechanically ventilated calves. Guaifenesin (150 mg/kg) decreases spectral edge frequency (SEF) and total power in pigs. Guaifenesin prevents adverse anesthetic induction events caused by Propofol in horse. Guaifenesin (90 mg/kg) followed by Propofol (3 mg/kg) should be sufficient to immobilize > 99% of calm healthy adult horses. Guaifenesin (100 mg/kg) produces moderate behavioral changes in the social conflict test in mice. Guaifenesin (200 mg/kg) combined with Paracetamol (200 mg/kg) causes significantly more pronounced analgesic effects that the corresponding doses of paracetamol alone in mice.
Cell Data

cell lines:

Concentrations:

Incubation Time:

Powder Purity:≥99%

Product Properties

ALogP 0.747
hba_count 2
HBD Count 2
Rotatable Bond 5

Names and Identifiers

Smiles COC1=C(OCC(O)CO)C=CC=C1
Molecular Weight 198.22
Reaxy-Rn 3200276
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=3200276&ln=

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Chemical and Physical Properties

DMSO(mg / mL) Max Solubility 40
DMSO(mM) Max Solubility 201.8
Water(mg / mL) Max Solubility 25
Water(mM) Max Solubility 126.12

Solution Calculators

Reviews

Customer Reviews

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