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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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G407746-1ml
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1ml |
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
|
$347.90
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Expectorant agent
| Synonyms | 3-(2-methoxyphenoxy)-1,2-propanediol |
|---|---|
| Specifications & Purity | Moligand™, 10mM in DMSO |
| Biochemical and Physiological Mechanisms | Guaifenesin is an expectorant used to relieve chest congestion. |
| Storage Temp | Store at -80°C |
| Shipped In |
Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available. |
| Grade | Moligand™ |
| Product Description |
Information Guaifenesin is an expectorant used to relieve chest congestion. In vivo Guaifenesin (200 mg/kg, intravenously) combined with ketamine (50 mg/kg, intramuscularly) produces effective and safe surgical anesthesia for over 30 minutes in New Zealand white rabbits. Guaifenesin (200 mg/kg, intravenously) combined with ketamine (50 mg/kg, intramuscularly) mildly depresses respiratory rate but heart rate and arterial blood pressure are not significantly affected. Guaifenesin (200 mg/kg, intravenously) is combined with sodium pentobarbital (20 mg/kg, intravenously) to produce surgical anesthesia for a period of more than 30 minutes. Guaifenesin (50 mg/mL) combined Xylazine (0.1 mg/mL) and Ketamine (1.0 mg/mL) results in excellent anesthetic induction and maintenance with cardiopulmonary alterations similar to those associated with isoflurane in mechanically ventilated calves. Guaifenesin (150 mg/kg) decreases spectral edge frequency (SEF) and total power in pigs. Guaifenesin prevents adverse anesthetic induction events caused by Propofol in horse. Guaifenesin (90 mg/kg) followed by Propofol (3 mg/kg) should be sufficient to immobilize > 99% of calm healthy adult horses. Guaifenesin (100 mg/kg) produces moderate behavioral changes in the social conflict test in mice. Guaifenesin (200 mg/kg) combined with Paracetamol (200 mg/kg) causes significantly more pronounced analgesic effects that the corresponding doses of paracetamol alone in mice. cell lines: Concentrations: Incubation Time: Powder Purity:≥99% |
| ALogP | 0.747 |
|---|---|
| hba_count | 2 |
| HBD Count | 2 |
| Rotatable Bond | 5 |
| Smiles | COC1=C(OCC(O)CO)C=CC=C1 |
|---|---|
| Molecular Weight | 198.22 |
| Reaxy-Rn | 3200276 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=3200276&ln= |
| DMSO(mg / mL) Max Solubility | 40 |
|---|---|
| DMSO(mM) Max Solubility | 201.8 |
| Water(mg / mL) Max Solubility | 25 |
| Water(mM) Max Solubility | 126.12 |