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GTP-γ-S-Li4 - ≥90%, high purity , CAS No.94825-44-2

    Grade & Purity:
  • ≥90%
In stock
Item Number
G276049
Grouped product items
SKU Size
Availability
Price Qty
G276049-1mg
1mg
Available within 1-2 weeks(?)
Item is derived from our semi-finished stock and is processed in 1-2 weeks.
$61.90
G276049-5mg
5mg
1
$213.90
G276049-10mg
10mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$270.90

G-protein-activating GTP analog

View related series
Membrane Transporter (607)

Basic Description

Synonyms Gtp-gamma-S-tetralithium | EINECS 305-606-1 | tetralithium;[[(2R,3S,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-oxidophosphoryl] dioxidophosphinothioyl phosphate | Guanosine 5'-(trihydrogen diphosphate), monoanhydride with phos
Specifications & Purity ≥90%
Biochemical and Physiological Mechanisms G-protein-activating GTP analog. More hydrolysis resistant than GTP. Stimulates insulin release from pancreatic β-cells. Inhibits organelle transport along axonal microtubules. Induces exocytosis in vivo.
Storage Temp Store at -20°C,Desiccated
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Note Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description

Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
Superclass Nucleosides, nucleotides, and analogues
Class Purine nucleotides
Subclass Purine ribonucleotides
Intermediate Tree Nodes Not available
Direct Parent Purine ribonucleoside diphosphates
Alternative Parents Purine ribonucleoside monophosphates  Pentose phosphates  Glycosylamines  Hypoxanthines  Monosaccharide phosphates  Organic pyrophosphates  Aminopyrimidines and derivatives  Alkyl phosphates  N-substituted imidazoles  Oxolanes  Heteroaromatic compounds  Secondary alcohols  1,2-diols  Oxacyclic compounds  Azacyclic compounds  Organic lithium salts  Organic zwitterions  Hydrocarbon derivatives  Primary amines  Organic oxides  
Molecular Framework Aromatic heteropolycyclic compounds
Substituents Purine ribonucleoside diphosphate - Purine ribonucleoside monophosphate - Pentose phosphate - Pentose-5-phosphate - Glycosyl compound - N-glycosyl compound - Hypoxanthine - Monosaccharide phosphate - Organic pyrophosphate - Pentose monosaccharide - Imidazopyrimidine - Purine - Aminopyrimidine - Alkyl phosphate - Pyrimidine - Monosaccharide - N-substituted imidazole - Phosphoric acid ester - Organic phosphoric acid derivative - Azole - Heteroaromatic compound - Oxolane - Imidazole - Secondary alcohol - 1,2-diol - Organic lithium salt - Oxacycle - Azacycle - Organic alkali metal salt - Organoheterocyclic compound - Organic salt - Organic oxide - Hydrocarbon derivative - Organonitrogen compound - Organooxygen compound - Organic oxygen compound - Organic nitrogen compound - Primary amine - Alcohol - Amine - Organic zwitterion - Aromatic heteropolycyclic compound
Description This compound belongs to the class of organic compounds known as purine ribonucleoside diphosphates. These are purine ribobucleotides with diphosphate group linked to the ribose moiety.
External Descriptors Not available

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Names and Identifiers

Pubchem Sid 488202914
Pubchem Sid Url https://pubchem.ncbi.nlm.nih.gov/substance/488202914
IUPAC Name tetralithium;[[(2R,3S,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-oxidophosphoryl] dioxidophosphinothioyl phosphate
INCHI InChI=1S/C10H16N5O13P3S.4Li/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(17)5(16)3(26-9)1-25-29(19,20)27-30(21,22)28-31(23,24)32;;;;/h2-3,5-6,9,16-17H,1H2,(H,19,20)(H,21,22)(H2,23,24,32)(H3,11,13,14,18);;;;/q;4*+1/p-4/t3-,5-,6-,9-;;;;/m1..../s1
InChIKey AMQXJFWJOAWCPV-ZVQJTLEUSA-J
Smiles [Li+].[Li+].[Li+].[Li+].C1=NC2=C(N1C3C(C(C(O3)COP(=O)([O-])OP(=O)([O-])OP(=S)([O-])[O-])O)O)N=C(NC2=O)N
Isomeric SMILES [Li+].[Li+].[Li+].[Li+].C1=NC2=C(N1[C@H]3[C@@H]([C@@H]([C@H](O3)COP(=O)([O-])OP(=O)([O-])OP(=S)([O-])[O-])O)O)N=C(NC2=O)N
WGK Germany 3
PubChem CID 135445735
Molecular Weight 567

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

12 results found

Lot Number Certificate Type Date Item
B2528098 Certificate of Analysis Mar 06, 2025 G276049
B2528099 Certificate of Analysis Mar 06, 2025 G276049
E2310484 Certificate of Analysis Feb 21, 2024 G276049
E2310485 Certificate of Analysis Feb 21, 2024 G276049
E2310498 Certificate of Analysis Jan 31, 2024 G276049
K2228601 Certificate of Analysis Sep 21, 2023 G276049
K2228549 Certificate of Analysis Sep 21, 2023 G276049
K2228578 Certificate of Analysis Sep 21, 2023 G276049
I2122106 Certificate of Analysis Apr 17, 2023 G276049
I2122193 Certificate of Analysis Apr 17, 2023 G276049
I2122212 Certificate of Analysis Jul 14, 2022 G276049
I2122213 Certificate of Analysis Jul 14, 2022 G276049

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Chemical and Physical Properties

Solubility Soluble in water to 100 mM
Molecular Weight 563.100 g/mol
XLogP3
Hydrogen Bond Donor Count 4
Hydrogen Bond Acceptor Count 16
Rotatable Bond Count 8
Exact Mass 563.001 Da
Monoisotopic Mass 563.001 Da
Topological Polar Surface Area 321.000 Ų
Heavy Atom Count 36
Formal Charge 0
Complexity 915.000
Isotope Atom Count 0
Defined Atom Stereocenter Count 4
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
The total count of all stereochemical bonds 0
Covalently-Bonded Unit Count 5

Solution Calculators

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