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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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G276049-1mg
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1mg |
Available within 1-2 weeks(?)
Item is derived from our semi-finished stock and is processed in 1-2 weeks.
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$61.90
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G276049-5mg
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5mg |
1
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$213.90
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G276049-10mg
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10mg |
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
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$270.90
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G-protein-activating GTP analog
| Synonyms | Gtp-gamma-S-tetralithium | EINECS 305-606-1 | tetralithium;[[(2R,3S,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-oxidophosphoryl] dioxidophosphinothioyl phosphate | Guanosine 5'-(trihydrogen diphosphate), monoanhydride with phos |
|---|---|
| Specifications & Purity | ≥90% |
| Biochemical and Physiological Mechanisms | G-protein-activating GTP analog. More hydrolysis resistant than GTP. Stimulates insulin release from pancreatic β-cells. Inhibits organelle transport along axonal microtubules. Induces exocytosis in vivo. |
| Storage Temp | Store at -20°C,Desiccated |
| Shipped In |
Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available. |
| Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
| Product Description |
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. |
Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Nucleosides, nucleotides, and analogues |
| Class | Purine nucleotides |
| Subclass | Purine ribonucleotides |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Purine ribonucleoside diphosphates |
| Alternative Parents | Purine ribonucleoside monophosphates Pentose phosphates Glycosylamines Hypoxanthines Monosaccharide phosphates Organic pyrophosphates Aminopyrimidines and derivatives Alkyl phosphates N-substituted imidazoles Oxolanes Heteroaromatic compounds Secondary alcohols 1,2-diols Oxacyclic compounds Azacyclic compounds Organic lithium salts Organic zwitterions Hydrocarbon derivatives Primary amines Organic oxides |
| Molecular Framework | Aromatic heteropolycyclic compounds |
| Substituents | Purine ribonucleoside diphosphate - Purine ribonucleoside monophosphate - Pentose phosphate - Pentose-5-phosphate - Glycosyl compound - N-glycosyl compound - Hypoxanthine - Monosaccharide phosphate - Organic pyrophosphate - Pentose monosaccharide - Imidazopyrimidine - Purine - Aminopyrimidine - Alkyl phosphate - Pyrimidine - Monosaccharide - N-substituted imidazole - Phosphoric acid ester - Organic phosphoric acid derivative - Azole - Heteroaromatic compound - Oxolane - Imidazole - Secondary alcohol - 1,2-diol - Organic lithium salt - Oxacycle - Azacycle - Organic alkali metal salt - Organoheterocyclic compound - Organic salt - Organic oxide - Hydrocarbon derivative - Organonitrogen compound - Organooxygen compound - Organic oxygen compound - Organic nitrogen compound - Primary amine - Alcohol - Amine - Organic zwitterion - Aromatic heteropolycyclic compound |
| Description | This compound belongs to the class of organic compounds known as purine ribonucleoside diphosphates. These are purine ribobucleotides with diphosphate group linked to the ribose moiety. |
| External Descriptors | Not available |
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| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
| Pubchem Sid | 488202914 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/488202914 |
| IUPAC Name | tetralithium;[[(2R,3S,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-oxidophosphoryl] dioxidophosphinothioyl phosphate |
| INCHI | InChI=1S/C10H16N5O13P3S.4Li/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(17)5(16)3(26-9)1-25-29(19,20)27-30(21,22)28-31(23,24)32;;;;/h2-3,5-6,9,16-17H,1H2,(H,19,20)(H,21,22)(H2,23,24,32)(H3,11,13,14,18);;;;/q;4*+1/p-4/t3-,5-,6-,9-;;;;/m1..../s1 |
| InChIKey | AMQXJFWJOAWCPV-ZVQJTLEUSA-J |
| Smiles | [Li+].[Li+].[Li+].[Li+].C1=NC2=C(N1C3C(C(C(O3)COP(=O)([O-])OP(=O)([O-])OP(=S)([O-])[O-])O)O)N=C(NC2=O)N |
| Isomeric SMILES | [Li+].[Li+].[Li+].[Li+].C1=NC2=C(N1[C@H]3[C@@H]([C@@H]([C@H](O3)COP(=O)([O-])OP(=O)([O-])OP(=S)([O-])[O-])O)O)N=C(NC2=O)N |
| WGK Germany | 3 |
| PubChem CID | 135445735 |
| Molecular Weight | 567 |
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | Mar 06, 2025 | G276049 | |
| Certificate of Analysis | Mar 06, 2025 | G276049 | |
| Certificate of Analysis | Feb 21, 2024 | G276049 | |
| Certificate of Analysis | Feb 21, 2024 | G276049 | |
| Certificate of Analysis | Jan 31, 2024 | G276049 | |
| Certificate of Analysis | Sep 21, 2023 | G276049 | |
| Certificate of Analysis | Sep 21, 2023 | G276049 | |
| Certificate of Analysis | Sep 21, 2023 | G276049 | |
| Certificate of Analysis | Apr 17, 2023 | G276049 | |
| Certificate of Analysis | Apr 17, 2023 | G276049 | |
| Certificate of Analysis | Jul 14, 2022 | G276049 | |
| Certificate of Analysis | Jul 14, 2022 | G276049 |
| Solubility | Soluble in water to 100 mM |
|---|---|
| Molecular Weight | 563.100 g/mol |
| XLogP3 | |
| Hydrogen Bond Donor Count | 4 |
| Hydrogen Bond Acceptor Count | 16 |
| Rotatable Bond Count | 8 |
| Exact Mass | 563.001 Da |
| Monoisotopic Mass | 563.001 Da |
| Topological Polar Surface Area | 321.000 Ų |
| Heavy Atom Count | 36 |
| Formal Charge | 0 |
| Complexity | 915.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 4 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 5 |