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Basic Description
| Synonyms | MFCD00004410 | NCGC00256456-01 | 1czc | CAS-110-94-1 | FT-0605446 | G0069 | Q409622 | 1,3-PENTANEDIOIC ACID (RIFM) | 1,5-Pentanedioate | 1,5-Pentanedioic acid | 1,3-Propanedicarboxylic acid | BRN 1209725 | Glutaric Acid (ca. 50% in Water, ca. 4.3mol/L) | |
|---|---|
| Specifications & Purity | ≥99% |
| Shipped In | Normal |
| Product Description |
Glutaric acid (Pentanedioic Acid) is a linear dicarboxylic acid. It has been prepared by oxidizing cyclopentane, cyclopentanol and cyclopentanone. Glutaric acid is a pentanedioic acid. On exposure to X-rays, glutaric acid crystals generate two stable free radicals. These free radicals have been investigated by electron nuclear double resonance (ENDOR) technique. Presence of glutaric acid in urine and plasma is an indicator of type I glutaric aciduria (GA-I). Glutaric acid is formed as an intermediate during the catabolism of lysine in mammals. Electron spin resonance spectra of radical (CO2H)CH2CH2CH(CO2H formed in glutaric acid crystal after γ-irradiation is reported to remains trapped in it. Polymorphism of Glycine-glutaric acid co-crystals has been studied by single crystal X-ray diffraction and Raman spectroscopy. |
Taxonomic Classification
Taxonomy Tree
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Kingdom
Organic compounds
- Superclass Organic acids and derivatives
| Kingdom | Organic compounds |
|---|---|
| Superclass | Organic acids and derivatives |
| Class | Carboxylic acids and derivatives |
| Subclass | Dicarboxylic acids and derivatives |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Dicarboxylic acids and derivatives |
| Alternative Parents | Fatty acids and conjugates Carboxylic acids Organic oxides Hydrocarbon derivatives Carbonyl compounds |
| Molecular Framework | Aliphatic acyclic compounds |
| Substituents | Fatty acid - Dicarboxylic acid or derivatives - Carboxylic acid - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Carbonyl group - Aliphatic acyclic compound |
| Description | This compound belongs to the class of organic compounds known as dicarboxylic acids and derivatives. These are organic compounds containing exactly two carboxylic acid groups. |
| External Descriptors | Dicarboxylic acids |
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Associated Targets(Human)
SLC22A8
Tclin
Solute carrier family 22 member 8 (241 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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SLC22A7
Tbio
Solute carrier family 22 member 7 (39 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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Associated Targets(non-human)
Slc22a20
Solute carrier family 22 member 20 (86 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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Slc22a6
Solute carrier family 22 member 6 (141 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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Mechanisms of Action
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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Names and Identifiers
| Pubchem Sid | 488179544 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/488179544 |
| IUPAC Name | pentanedioic acid |
| INCHI | InChI=1S/C5H8O4/c6-4(7)2-1-3-5(8)9/h1-3H2,(H,6,7)(H,8,9) |
| InChIKey | JFCQEDHGNNZCLN-UHFFFAOYSA-N |
| Smiles | C(CC(=O)O)CC(=O)O |
| Isomeric SMILES | C(CC(=O)O)CC(=O)O |
| WGK Germany | 1 |
| RTECS | MA3740000 |
| Molecular Weight | 132.11 |
| Beilstein | 1209725 |
| Reaxy-Rn | 1209725 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1209725&ln= |
Certificates（CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 D2514343 |
Certificate of Analysis | Mar 31, 2025 | G103516 |
| D2514344 |
Certificate of Analysis | Mar 31, 2025 | G103516 |
| D2514345 |
Certificate of Analysis | Mar 31, 2025 | G103516 |
| D2514383 |
Certificate of Analysis | Mar 31, 2025 | G103516 |
| G2426284 |
Certificate of Analysis | Jul 15, 2024 | G103516 |
| G2426283 |
Certificate of Analysis | Jul 15, 2024 | G103516 |
| G2426285 |
Certificate of Analysis | Jul 15, 2024 | G103516 |
| G2426286 |
Certificate of Analysis | Jul 15, 2024 | G103516 |
| G2405303 |
Certificate of Analysis | Apr 27, 2024 | G103516 |
| G2405310 |
Certificate of Analysis | Apr 27, 2024 | G103516 |
| G2405311 |
Certificate of Analysis | Apr 27, 2024 | G103516 |
| B2306817 |
Certificate of Analysis | Feb 11, 2023 | G103516 |
| B2306821 |
Certificate of Analysis | Feb 10, 2023 | G103516 |
| A2410028 |
Certificate of Analysis | Feb 06, 2023 | G103516 |
| C2415097 |
Certificate of Analysis | Feb 06, 2023 | G103516 |
| C2310189 |
Certificate of Analysis | Feb 06, 2023 | G103516 |
| C2310113 |
Certificate of Analysis | Feb 06, 2023 | G103516 |
| C2310173 |
Certificate of Analysis | Feb 06, 2023 | G103516 |
| H1814067 |
Certificate of Analysis | Jun 17, 2022 | G103516 |
| E2207081 |
Certificate of Analysis | Mar 26, 2022 | G103516 |
| E2207101 |
Certificate of Analysis | Mar 26, 2022 | G103516 |
| E2207076 |
Certificate of Analysis | Mar 26, 2022 | G103516 |
| E2207106 |
Certificate of Analysis | Mar 26, 2022 | G103516 |
| B2218030 |
Certificate of Analysis | Feb 22, 2022 | G103516 |
| B2218026 |
Certificate of Analysis | Feb 22, 2022 | G103516 |
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Chemical and Physical Properties
| Solubility | Soluble in water, alcohol, benzene and chloroform. Slightly soluble in petroleum ether. |
|---|---|
| Boil Point(°C) | 200°C |
| Melt Point(°C) | 92-99°C |
| Molecular Weight | 132.110 g/mol |
| XLogP3 | -0.300 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 4 |
| Rotatable Bond Count | 4 |
| Exact Mass | 132.042 Da |
| Monoisotopic Mass | 132.042 Da |
| Topological Polar Surface Area | 74.600 Ų |
| Heavy Atom Count | 9 |
| Formal Charge | 0 |
| Complexity | 104.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
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Citations of This Product
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| 2. Weiwei Zhang, Zhijun Yao, Hao Liu, Jiahao Liu, Mingyu Li, Fuquan Li, Hongtao Chen. (2023) Electrical and mechanical reliability and failure mechanism analysis of electrically conductive adhesives. MICROELECTRONICS RELIABILITY, 151 (115236). |
| 3. Yongqi Yang, Chunyang Lv, Chang Tan, Jingfang Li, Xin Wang. (2023) Easy-to-Prepare Flexible Multifunctional Sensors Assembled with Anti-Swelling Hydrogels. ACS Applied Materials & Interfaces, 15 (39): (46417–46427). |
| 4. Guang Huang, Honglei Guo, Zhuofu Tang, Shuaiwei Peng, Huansen Liang, Guozhe Meng, Ping Zhang. (2023) Tough Hydrophobic Hydrogels for Monitoring Human Moderate Motions in Both Air and Underwater Environments. CHEMISTRY OF MATERIALS, 35 (15): (5953–5962). |
| 5. Xin Guo, Min Wu, Yanping Deng, Yan Liu, Yanpeng Liu, Jianhua Xu. (2023) Redox-Responsive Lipidic Prodrug Nano-Delivery System Improves Antitumor Effect of Curcumin Derivative C210. Pharmaceutics, 15 (5): (1546). |
| 6. Man Zhang, Rubo Tian, Siyang Tang, Kejing Wu, Binshen Wang, Yingying Liu, Yingming Zhu, Houfang Lu, Bin Liang. (2023) Multistage treatment of bamboo powder waste biomass: Highly efficient and selective isolation of lignin components. WASTE MANAGEMENT, 166 (35). |
| 7. Qingdong Liao, Zhen Liu. (2023) In-situ solvothermally grown hexagonal tungsten oxide films on FTO coated glasses for electrochromic applications. Materials Today Communications, 35 (105989). |
| 8. Xingjian Sun, Ping Rao, Xitao He, Canhui Yang, Wei Hong. (2023) Chemically identical gels I – under-crosslinked networks. JOURNAL OF THE MECHANICS AND PHYSICS OF SOLIDS, 175 (105278). |
| 9. Yajie Wang, Xin Dong, Chengfeng Liu, Peng Cheng, Gilles Mailhot. (2023) Efficient Decolorization of Azo Dye Orange II in a UV-Fe3+-PMS-Oxalate System. Processes, 11 (3): (903). |
| 10. Xiaodong Wan, Yunfeng He, Caicong Li, Canhui Yang. (2023) Encapsulating eutectogels for stretchable humidity-resistant strain sensors. Soft Matter, 19 (14): (2570-2578). |
| 11. Chang Cong, Jixiao Wang, Zhan Wang, Guangyu Xing, Zhi Wang. (2023) Photothermal healing performance of oxidized carbon black/epoxy vitrimer composite coating for metal protection. PROGRESS IN ORGANIC COATINGS, 179 (107484). |
| 12. Yifei Zheng, Chao Qin, Fei Li, Jingxin Qi, Xinyu Chu, Hao Li, Ting Shi, Zhen Yan, Lei Yang, Xiaofei Xin, Lisha Liu, Xiaopeng Han, Lifang Yin. (2023) Self-assembled thioether-bridged paclitaxel-dihydroartemisinin prodrug for amplified antitumor efficacy-based cancer ferroptotic-chemotherapy. Biomaterials Science, 11 (9): (3321-3334). |
| 13. Shilei Zhu, Dongdong Yan, Lin Chen, Yan Wang, Fengbo Zhu, Yanan Ye, Yong Zheng, Wenwen Yu, Qiang Zheng. (2023) Enhanced Rupture Force in a Cut-Dispersed Double-Network Hydrogel. Gels, 9 (2): (158). |
| 14. Shilei Zhu, Yan Wang, Zhe Wang, Lin Chen, Fengbo Zhu, Yanan Ye, Yong Zheng, Wenwen Yu, Qiang Zheng. (2023) Metal-Coordinated Dynamics and Viscoelastic Properties of Double-Network Hydrogels. Gels, 9 (2): (145). |
| 15. Chang Cong, Jixiao Wang, Guangyu Xing, Zhan Wang, Sicheng Yuan, Zhi Wang. (2023) Photothermal process and its stimulate healing performance for catalyst-free OCB/epoxy vitrimer composite. SOLAR ENERGY MATERIALS AND SOLAR CELLS, 252 (112204). |
| 16. Wenzhen Wang, Xiangmin Zhang, Weiwei Han, Jian Huang, Yile Zhang, Chen Zhao, Leilei Li. (2023) A one-pot strategy for the preparation of fire-retardant poly(propylene carbonate) by terpolymerization of CO2, propylene oxide and chlorendic anhydride. Materials Today Communications, 34 (105179). |
| 17. Tianqi Niu, Fuchao Zhen, Yue-Min Xie, Tinghuan Yang, Qin Yao, Jing Lu, Kui Zhao, Hin-Lap Yip. (2022) Molecularly Functionalized SnO2 Films by Carboxylic Acids for High-Performance Perovskite Solar Cells. ACS Applied Materials & Interfaces, 14 (47): (52838–52848). |
| 18. Zhang Yan, Wang Yafei, Guan Ying, Zhang Yongjun. (2022) Peptide-enhanced tough, resilient and adhesive eutectogels for highly reliable strain/pressure sensing under extreme conditions. Nature Communications, 13 (1): (1-12). |
| 19. Weiwei Zhang, Jiahao Liu, Hao Liu, Jianqiang Wang, Luobin Zhang, Jintao Wang, Haozhong Wang, Fengyi Wang, Xinjie Wang, Fuwen Yu, Ziwen Lv, Zheng Zhang, Chunjin Hang, Mingyu Li, Hongtao Chen. (2022) Surface Functionalization of Micrometer Silver Flakes for Fabricating High-Performance Electrically Conductive Adhesives. ACS Applied Electronic Materials, 4 (11): (5387–5396). |
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| 21. Zheming Zhang, Pingping Jiang, Phyu Thin Wai, Shan Feng, Minjia Lu, Pingbo Zhang, Yan Leng, Lingen Pan, Jie Pan. (2022) Construction and Synthesis of High-Stability Biobased Oligomeric Lactate Plasticizer: Applicable to PVC and PLA Polymers. INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH, 61 (35): (12931–12941). |
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| 27. Yangyi Huang, Lin Zhang, Mengqi Yan, Qinan Huang, Yuning Zhang, Yanqun Ren, Weiping Luo. (2022) Measurement and Correlation for Solubilities of Adipic Acid, Glutaric Acid, and Succinic Acid in Different Alcohol Solvents. JOURNAL OF CHEMICAL AND ENGINEERING DATA, 67 (1): (245–256). |
| 28. Shahid Hussain, Haifeng Dong, Yanqiang Zhang, Guoxiong Zhan, Shaojuan Zeng, Huifang Duan, Xiangping Zhang. (2022) Impregnation of 1-n-Butyl-3-methylimidazolium Dicyanide [BMIM][DCA] into ZIF-8 as a Versatile Sorbent for Efficient and Selective Separation of CO2. INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH, 61 (1): (706–715). |
| 29. Shijie Xu, Yaqing Bu, Shuwan Jiang, Penghui Yang, Yanfei Wang. (2021) Insights into the Role of Solvents in Nucleation Kinetics of Glutaric Acid from Metastable Zone Widths. INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH, 60 (7): (3073–3082). |
| 30. Keliang Zhang, Jun Gao, Shangji Li, Ting Ma, Linhong Deng, Yong Kong. (2021) Construction of a pH-responsive drug delivery platform based on the hybrid of mesoporous silica and chitosan. Journal of Saudi Chemical Society, 25 (101174). |
| 31. Danping Li, Xun-an Ning, Yiqian Yuan, Yanxiang Hong, Jianpei Zhang. (2020) Ion-exchange polymers modified bacterial cellulose electrodes for the selective removal of nitrite ions from tail water of dyeing wastewater. Journal of Environmental Sciences, 91 (62). |
| 32. Bo Chen, Mengqi Yan, Bao Tao, Lintao Yang, Weiping Luo. (2020) Solubilities of Adipic Acid, Glutaric Acid, and Succinic Acid in Dimethyl Glutarate + Methanol Mixtures: Experimental Measurement and Thermodynamic Modeling. JOURNAL OF CHEMICAL AND ENGINEERING DATA, 65 (1): (56–67). |
| 33. Sile Shi, Mengqi Yan, Bao Tao, Weiping Luo. (2020) Measurement and correlation for solubilities of succinic acid, glutaric acid and adipic acid in five organic solvents. JOURNAL OF MOLECULAR LIQUIDS, 297 (111735). |
| 34. Lipeng Wang, Qing Zhu, Yongping Bai. (2019) Synthesis and characterizations of a series of water soluble polyamides and their micellization behavior. POLYMER, 179 (121634). |
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| 52. Tao Liu, Youcai Zhu, Yue Mu, Xindi Feng, Zhen Liu. (2025) Enhanced activity for producing CO2-based polyols enabled by Zn-Co DMC/c-CTA catalytic system. Molecular Catalysis, 571 (114693). |
| 53. Hongmei Luo, Lichao Jiang, Yuxin Guo, Min Li, Longyu Hu, Hao Wu, Wei Cui, Rong Ran. (2024) Extreme Toughening of Conductive Hydrogels Through Synergistic Effects of Mineralization, Salting-Out, and Ion Coordination Induced by Multivalent Anions. Small, (2409565). |
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