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Glipizide - 10mM in DMSO, high purity , CAS No.29094-61-9(DMSO), Sulfonylurea receptor 1, Kir6.2 blocker

In stock
Item Number
G408514
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Availability
Price Qty
G408514-1ml
1ml
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$151.90

Potassium Channel Inhibitors

View related series
Compound libraries (12325)

Basic Description

Synonyms CP-28720 | N-​[2-​[4-​[[[(cyclohexylamino)​carbonyl]​amino]​sulfonyl]​phenyl]​ethyl]​-​5-​methyl-2-​pyrazinecarboxamide
Specifications & Purity Moligand™, 10mM in DMSO
Biochemical and Physiological Mechanisms Glipizide (CP-28720) is used to treat high blood sugar levels caused by a type of diabetes mellitus called type 2 diabetes.
Storage Temp Store at -80°C
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Grade Moligand™
Action Type BLOCKER
Mechanism of action Sulfonylurea receptor 1, Kir6.2 blocker
Product Description

Information

Glipizide Glipizide (CP-28720) is used to treat high blood sugar levels caused by a type of diabetes mellitus called type 2 diabetes.
In vitro


In vivo


Cell Data

cell lines:

Concentrations:

Incubation Time:

Powder Purity:≥99%

Product Properties

ALogP 1.902
hba_count 6
HBD Count 3
Rotatable Bond 7

Names and Identifiers

Smiles CC1=NC=C(N=C1)C(=O)NCCC2=CC=C(C=C2)[S](=O)(=O)NC(=O)NC3CCCCC3
Molecular Weight 445.54
Reaxy-Rn 903495
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=903495&ln=

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Chemical and Physical Properties

DMSO(mg / mL) Max Solubility 89
DMSO(mM) Max Solubility 199.76
Water(mg / mL) Max Solubility <1

Citations of This Product

1. Zixian He, Zhiwei Liu, Haihuan Xie, Pengjie Luo, Xiangmei Li.  (2023)  An Ultrasensitive Lateral Flow Immunoassay Based on Metal-Organic Framework-Decorated Polydopamine for Multiple Sulfonylureas Adulteration in Functional Foods.  Foods,  12  (3): (539). 
2. Sun Zhiping, He Lingli, Yang Qingqing, Zhang Haizhi, Xu Weiren, Qin Xinguang, Liu Gang, Hu Zhongze, Zhang Luyong, Liu Changxiao.  (2022)  Study on the Effect of Three CYP2C9 Variants on Drug–Drug Interaction Related to Six Drugs In Vitro by LC–MS/MS Method.  CHROMATOGRAPHIA,  85  (3): (221-231). 
3. Haihuan Xie, Yingying Li, Jin Wang, Yi Lei, Anastasios Koidis, Xiangmei Li, Xing Shen, Zhenlin Xu, Hongtao Lei.  (2022)  Broad-specific immunochromatography for simultaneous detection of various sulfonylureas in adulterated multi-herbal tea.  FOOD CHEMISTRY,  370  (131055). 
4. Zhengyong Wang, Yuqi Cao, Yingjie Lu, Fang Zhang, Yue Su, Yinlong Guo.  (2020)  Ultrasonic extraction and nebulization in real-time coupled with carbon fiber ionization mass spectrometry for rapid screening of the synthetic drugs adulterated into herbal products.  ANALYTICA CHIMICA ACTA,  1136  (62). 

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