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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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Ab190291-10μg
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10μg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$56.90
|
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Ab190291-25μg
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25μg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$103.90
|
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Ab190291-100μg
|
100μg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$278.90
|
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mAb (DTA-1); Rat anti Mouse GITR/CD357 Antibody (PE); Flow Cytometry
| Product Name | GITR/CD357 Rat mAb (PE) - Primary antibody, specific to GITR/CD357 |
|---|---|
| Specifications & Purity | ExactAb™, Validated, 0.5 mg/mL |
| Biochemical and Physiological Mechanisms | Receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway. |
| Host species | Rat |
| Specificity | GITR/CD357 |
| Immunogen | Mouse CD25+ CD4+ T cells |
| Positive Control | Flow: C57BL/6 mouse splenocytes. |
| Conjugation | PE |
| Excitation(nm) | Blue Laser(488nm), Green Laser(532nm), Yellow-Green Laser(561nm) |
| Emission(nm) | 575nm |
| Ex/Em(nm) | Ex:565nm;Em:575nm |
| Grade | ExactAb™, Validated |
| Product Description |
Rat anti Mouse GITR/CD357 Antibody, Monoclonal (DTA-1), could be used for Flow Cytometry. |
| Light Chain Type | lambda |
|---|---|
| Purification Method | Protein G purified |
| Concentration | 0.5 mg/mL |
| Storage Temp | Store at 2-8°C,Protected from light,Do not freeze |
| Shipped In | Wet ice |
| Stability And Storage | The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze. |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
GITR/CD357 Rat mAb (PE) (Ab190291) - Flow Cytometry
Two-color flow cytometric analysis of GITR/CD357 expression on mouse splenocytes. C57BL/6 mouse spleen cells were stained with CD25 Rat mAb (AF647) (Ab211659) and either Rat IgG (PE) (Ab180312; Left panel) or GITR/CD357 Rat mAb (PE) (Ab190291; Right panel) at 0.3 μg/test.
| Application | Dilution info |
|---|---|
| Flow Cytometry | ≤1.0μg/ test For flow cytometric staining, the suggested use of this reagent is ≤1.0 μg per million cells in 100 µL staining volume. |