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Ginsenoside F2 - ≥98%, high purity , CAS No.62025-49-4

1 Citations COA COA
    Grade & Purity:
  • ≥98%
In stock
Item Number
G274780
Grouped product items
SKU Size
Availability
 Price Qty
G274780-1mg
1mg
3
$109.90
G274780-5mg
5mg
3
$280.90
G274780-10mg
10mg
2
$484.90
G274780-25mg
25mg
1
$1,090.90
G274780-100mg
100mg
1
$3,924.90
Wish List
Bulk Order  SDS  DATASHEET  Specification Sheet

Apoptotic and antiproliferative agent

View related series
Apoptosis (4276) Autophagy (1917) Metabolite (5307)

Basic Description

Synonyms MFCD06410948 | (20S)-ginsenoside F2 | SWIROVJVGRGSPO-JBVRGBGGSA-N | (2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-[[(3S,5R,8R,9R,10R,12R,13R,14R, 17S)-12-hydroxy-4,4,8,10,14-pentamethyl-17-[(2S)-6-methyl-2-[(2S,3R,4S, 5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-
Specifications & Purity ≥98%
Biochemical and Physiological Mechanisms Apoptotic and antiproliferative agent. Minor ginsenoside converted from Rb 1. Induces apoptosis through multiple pathways (IC 50 = 60 nM). Shows antitumor effects in vivo. Orally active.
Source Synthetic
Storage Temp Store at -20°C
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Note Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
Superclass Lipids and lipid-like molecules
Class Prenol lipids
Subclass Terpene glycosides
Intermediate Tree Nodes Triterpene glycosides
Direct Parent Triterpene saponins
Alternative Parents Triterpenoids  Steroidal glycosides  12-hydroxysteroids  14-alpha-methylsteroids  Fatty acyl glycosides of mono- and disaccharides  Alkyl glycosides  O-glycosyl compounds  Oxanes  Monosaccharides  Secondary alcohols  Cyclic alcohols and derivatives  Polyols  Acetals  Oxacyclic compounds  Primary alcohols  Hydrocarbon derivatives  
Molecular Framework Aliphatic heteropolycyclic compounds
Substituents Triterpene saponin - Triterpenoid - Steroidal glycoside - 12-hydroxysteroid - 14-alpha-methylsteroid - Hydroxysteroid - Steroid - Fatty acyl glycoside - Fatty acyl glycoside of mono- or disaccharide - Alkyl glycoside - Glycosyl compound - O-glycosyl compound - Fatty acyl - Monosaccharide - Oxane - Cyclic alcohol - Secondary alcohol - Polyol - Acetal - Organoheterocyclic compound - Oxacycle - Hydrocarbon derivative - Organic oxygen compound - Primary alcohol - Alcohol - Organooxygen compound - Aliphatic heteropolycyclic compound
Description This compound belongs to the class of organic compounds known as triterpene saponins. These are glycosylated derivatives of triterpene sapogenins. The sapogenin moiety backbone is usually based on the oleanane, ursane, taraxastane, bauerane, lanostane, lupeol, lupane, dammarane, cycloartane, friedelane, hopane, 9b,19-cyclo-lanostane, cycloartane, or cycloartanol skeleton.
External Descriptors beta-D-glucoside - tetracyclic triterpenoid - 12beta-hydroxy steroid - ginsenoside

Associated Targets(Human)

TOP1 Tclin DNA topoisomerase I (7553 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
TOP2A Tclin DNA topoisomerase II alpha (6317 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
HL-60 (67320 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
PANC-1 (6144 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
PC-3 (62116 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
U-251 (51189 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
A549 (127892 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Names and Identifiers

Pubchem Sid 504765091
Pubchem Sid Url https://pubchem.ncbi.nlm.nih.gov/substance/504765091
IUPAC Name (2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-[[(3S,5R,8R,9R,10R,12R,13R,14R,17S)-12-hydroxy-4,4,8,10,14-pentamethyl-17-[(2S)-6-methyl-2-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhept-5-en-2-yl]-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]oxane-3,4,5-triol
INCHI InChI=1S/C42H72O13/c1-21(2)10-9-14-42(8,55-37-35(51)33(49)31(47)25(20-44)53-37)22-11-16-41(7)29(22)23(45)18-27-39(5)15-13-28(38(3,4)26(39)12-17-40(27,41)6)54-36-34(50)32(48)30(46)24(19-43)52-36/h10,22-37,43-51H,9,11-20H2,1-8H3/t22-,23+,24+,25+,26-,27+,28-,29-,30+,31+,32-,33-,34+,35+,36-,37-,39-,40+,41+,42-/m0/s1
InChIKey SWIROVJVGRGSPO-JBVRGBGGSA-N
Smiles CC(=CCCC(C)(C1CCC2(C1C(CC3C2(CCC4C3(CCC(C4(C)C)OC5C(C(C(C(O5)CO)O)O)O)C)C)O)C)OC6C(C(C(C(O6)CO)O)O)O)C
Isomeric SMILES CC(=CCC[C@@](C)([C@H]1CC[C@@]2([C@@H]1[C@@H](C[C@H]3[C@]2(CC[C@@H]4[C@@]3(CC[C@@H](C4(C)C)O[C@H]5[C@@H]([C@H]([C@@H]([C@H](O5)CO)O)O)O)C)C)O)C)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O)C
PubChem CID 9918692
Molecular Weight 785.01

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

6 results found

Lot Number Certificate Type Date Item
E2528153 Certificate of Analysis Jun 04, 2025 G274780
G2207179 Certificate of Analysis Apr 17, 2023 G274780
G2207178 Certificate of Analysis Apr 17, 2023 G274780
G2207182 Certificate of Analysis Apr 17, 2023 G274780
G2207181 Certificate of Analysis Apr 17, 2023 G274780
G2207180 Certificate of Analysis Apr 17, 2023 G274780

Chemical and Physical Properties

Sensitivity Heat Sensitive
Melt Point(°C) 185 °C
Molecular Weight 785.000 g/mol
XLogP3 4.000
Hydrogen Bond Donor Count 9
Hydrogen Bond Acceptor Count 13
Rotatable Bond Count 10
Exact Mass 784.497 Da
Monoisotopic Mass 784.497 Da
Topological Polar Surface Area 219.000 Ų
Heavy Atom Count 55
Formal Charge 0
Complexity 1370.000
Isotope Atom Count 0
Defined Atom Stereocenter Count 20
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
The total count of all stereochemical bonds 0
Covalently-Bonded Unit Count 1

Citations of This Product

How to Cite Aladdin Scientific Products?
1. Jiahong Han, Min Dai, Yan Zhao, Enbo Cai, Lianxue Zhang, Xiaohuan Jia, Nian Sun, Xuan Fei, Hui Shu.  (2020)  Compatibility effects of ginseng and Ligustrum lucidum Ait herb pair on hematopoietic recovery in mice with cyclophosphamide-induced myelosuppression and its material basis.  Journal of Ginseng Research,  44  (291). 

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