Basic Description

Synonyms	W-104430 \| 5'-GDP-Na2 \| A838035 \| SCHEMBL5172376 \| HG1322 \| F19215 \| Guanosine-5,-diphosphate disodium \| Guanosine-5'-diphosphate disodium salt \| Guanosine 5'-diphosphate disodium salt \| Disodium 5'-O-{[(hydroxyphosphinato)oxy]phosphinato}guanosine \| Guan
Specifications & Purity	≥90%
Biochemical and Physiological Mechanisms	Nucleoside diphosphate used as a substrate of pyruvate kinase to produce GTP in support of RNA biosynthesis. Used to study the kinetics and characteristics of GTPases such as those associated with G-protein coupled receptors (GPCR).
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available.
Note	Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description	Guanosine 5′-diphosphate (GDP) is used as a substrate of pyruvate kinase to produce GTP in support of RNA biosyntheis. GDP is used to study the kinetics and characteristics of GTPases such as those associated with G-protein coupled receptors (GPCR). GDP is also used to study cell signaling processes mediate by guanine nucleotide exchange factors.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Nucleosides, nucleotides, and analogues
  - Class Purine nucleotides
    - Subclass Purine ribonucleotides

Kingdom	Organic compounds
Superclass	Nucleosides, nucleotides, and analogues
Class	Purine nucleotides
Subclass	Purine ribonucleotides
Intermediate Tree Nodes	Not available
Direct Parent	Purine ribonucleoside diphosphates
Alternative Parents	Purine ribonucleoside monophosphates Pentose phosphates Glycosylamines 6-oxopurines Hypoxanthines Monosaccharide phosphates Organic pyrophosphates Aminopyrimidines and derivatives Pyrimidones Monoalkyl phosphates N-substituted imidazoles Vinylogous amides Heteroaromatic compounds Oxolanes Secondary alcohols 1,2-diols Oxacyclic compounds Azacyclic compounds Hydrocarbon derivatives Primary amines Organic zwitterions Organic sodium salts Organic oxides
Molecular Framework	Aromatic heteropolycyclic compounds
Substituents	Purine ribonucleoside diphosphate - Purine ribonucleoside monophosphate - Pentose-5-phosphate - Pentose phosphate - N-glycosyl compound - Glycosyl compound - Hypoxanthine - Monosaccharide phosphate - Organic pyrophosphate - Purinone - Pentose monosaccharide - 6-oxopurine - Imidazopyrimidine - Purine - Pyrimidone - Aminopyrimidine - Monoalkyl phosphate - Monosaccharide - N-substituted imidazole - Organic phosphoric acid derivative - Phosphoric acid ester - Alkyl phosphate - Pyrimidine - Vinylogous amide - Azole - Heteroaromatic compound - Oxolane - Imidazole - Secondary alcohol - 1,2-diol - Organoheterocyclic compound - Oxacycle - Azacycle - Organic alkali metal salt - Organic oxygen compound - Amine - Organooxygen compound - Organic sodium salt - Hydrocarbon derivative - Organic oxide - Primary amine - Organic salt - Organonitrogen compound - Organic nitrogen compound - Alcohol - Organic zwitterion - Aromatic heteropolycyclic compound
Description	This compound belongs to the class of organic compounds known as purine ribonucleoside diphosphates. These are purine ribobucleotides with diphosphate group linked to the ribose moiety.
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Names and Identifiers

Pubchem Sid	504773442
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/504773442
IUPAC Name	disodium;[[(2R,3S,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-oxidophosphoryl] hydrogen phosphate
INCHI	InChI=1S/C10H15N5O11P2.2Na/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(17)5(16)3(25-9)1-24-28(22,23)26-27(19,20)21;;/h2-3,5-6,9,16-17H,1H2,(H,22,23)(H2,19,20,21)(H3,11,13,14,18);;/q;2*+1/p-2/t3-,5-,6-,9-;;/m1../s1
InChIKey	LTZCGDIGAHOTKN-LGVAUZIVSA-L
Smiles	C1=NC2=C(N1C3C(C(C(O3)COP(=O)([O-])OP(=O)(O)[O-])O)O)N=C(NC2=O)N.[Na+].[Na+]
Isomeric SMILES	C1=NC2=C(N1[C@H]3[C@@H]([C@@H]([C@H](O3)COP(=O)([O-])OP(=O)(O)[O-])O)O)N=C(NC2=O)N.[Na+].[Na+]
Alternate CAS	43139-22-6
PubChem CID	135818279
Molecular Weight	487.17

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

7 results found

Lot Number	Certificate Type	Date	Item
L1825134	Certificate of Analysis	Oct 18, 2022	G104781
K2212322	Certificate of Analysis	Jun 30, 2022	G104781
K2212366	Certificate of Analysis	Jun 30, 2022	G104781
K2212384	Certificate of Analysis	Jun 30, 2022	G104781
K2212370	Certificate of Analysis	Jun 30, 2022	G104781
K2212330	Certificate of Analysis	Jun 30, 2022	G104781
G2213563	Certificate of Analysis	Oct 23, 2021	G104781

Chemical and Physical Properties

Solubility	Soluble in water
Molecular Weight	487.160 g/mol
XLogP3
Hydrogen Bond Donor Count	5
Hydrogen Bond Acceptor Count	13
Rotatable Bond Count	6
Exact Mass	486.988 Da
Monoisotopic Mass	486.988 Da
Topological Polar Surface Area	254.000 Å²
Heavy Atom Count	30
Formal Charge	0
Complexity	750.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	4
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	3

Citations of This Product

How to Cite Aladdin Scientific Products?

1. Guimei Wang, Xiaoxue Jiang, Nanyan Fu. (2019) Near-infrared squaraine fluorescent probe for imaging adenosine 5′-triphosphate in live cells. DYES AND PIGMENTS, 171 (107698).
2. Fan Huahua, Wang Runjia, Zhang Li, Liu Minghua. (2025) Amplified circularly polarized luminescence in assembly of terpyridine-ZnII and GTP induced by silver(I) ion. Science China-Chemistry, (1-10).

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SKU	Size	Availability	Price
G104781-100mg	100mg	3	$108.90
G104781-250mg	250mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$243.90
G104781-500mg	500mg	3	$380.90
G104781-1g	1g	3	$684.90
G104781-5g	5g	3	$3,078.90
G104781-25g	25g	3	$13,851.90

GDP Disodium Salt - 90%, high purity , CAS No.7415-69-2