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GB-110 hydrochloride - 99%, high purity , CAS No.G659189

COA

Grade & Purity:

≥99%

Molecular Weight: 645.23

In stock

Item Number

G659189

Grouped product items
SKU	Size	Availability	Price
G659189-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$350.90
G659189-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$550.90
G659189-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$990.90
G659189-50mg	50mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,650.90
G659189-100mg	100mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$2,250.90

View related series

GPCR/G Protein (3172) Protease Activated Receptor (PAR) (55)

Basic Description

Specifications & Purity	≥99%
Storage Temp	Store at 2-8°C,Desiccated
Shipped In	Wet ice This product requires cold chain shipping. Ground and other economy services are not available.
Product Description	GB-110 hydrochloride is a potent, orally active, and nonpeptidic protease activated receptor 2 (PAR2) agonist. GB-110 hydrochloride selectively induces PAR2-mediated intracellular Ca 2+ release in HT29 cells with an EC 50 of 0.28 μM. Appearance:Solid IC50& Target:PAR2 In Vitro:In an intracellular Ca 2+ (iCa 2+ ) mobilization assay using HT29 colon cancer cells, GB110 (EC 50 240±20 nM; pEC 50 6.7±0.05) is equipotent with the peptide agonist 2f-LIGRLO-NH2 (EC 50 210±30 nM; pEC 50 6.6±0.05), 10-fold more potent than SLIGRL-NH2, bu Biological Activity:GB-110 hydrochloride is a potent, orally active, and nonpeptidic protease activated receptor 2 (PAR2) agonist. GB-110 hydrochloride selectively induces PAR2-mediated intracellular Ca 2+ release in HT29 cells with an EC 50 of 0.28 μM.

Names and Identifiers

Smiles	O=C(C1=CC=NO1)N[C@@H](CC2CCCCC2)C(N[C@@H]([C@@H](C)CC)C(NCC3=CC=CC(C(N4CCC(CN)CC4)=O)=C3)=O)=O.Cl
Molecular Weight	645.23

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Chemical and Physical Properties

Solubility	DMSO : 125 mg/mL (193.73 mM; Need ultrasonic) H2O : 25 mg/mL (38.75 mM; Need ultrasonic)

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