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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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Ab177850-100μg
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100μg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$59.90
|
|
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Ab177850-1mg
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1mg |
5
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$279.90
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Ab177850-5mg
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5mg |
1
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$909.90
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|
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Ab177850-10mg
|
10mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$1,429.90
|
|
Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
| Product Name | Galiximab (anti-CD80) - Primary antibody, specific to CD80, >95%, high purity, Human IgG1, INHIBITOR of T-lymphocyte activation antigen CD80 inhibitor |
|---|---|
| Synonyms | Activation B7-1 antigen | B7 | BB1 | CTLA-4 counter-receptor B7.1 |
| Specifications & Purity | Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA |
| Host species | Human |
| Specificity | CD80 |
| Conjugation | Unconjugated |
| Grade | Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated |
| Action Type | INHIBITOR |
| Mechanism of action | INHIBITOR of T-lymphocyte activation antigen CD80 inhibitor |
| Product Description |
Galiximab (anti-CD80) is a primatized immunoglobulin G1 (IgG1) lambda monoclonal antibody directed against the CD80 antigen. Galiximab (anti-CD80) has variable regions are primatized (cynomologous monkeys), and the constant regions are human. Galiximab (anti-CD80) can be used in research of B-cell lymphoma. |
| Isotype | Human IgG1 |
|---|---|
| Light Chain Type | lambda |
| SDS-PAGE | 28.8 kDa (Light Chain) & 51.6 kDa (Heavy Chain), under reducing conditions; 183.4 kDa, under non-reducing conditions. |
| Purification Method | Protein A purified |
| Purity | >95% |
| Shape | Liquid |
| Concentration | See COA |
| Storage Temp | Store at -80°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle. |
| CAS | 357613-77-5 |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
Galiximab (anti-CD80) (Ab177850) - Flow Cytometry
Flow Cytometry analysis of Raji cells labelling CD80 (red) with Galiximab (anti-CD80) (Ab177850). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.
Galiximab (anti-CD80) (Ab177850) - SEC
The purity of Galiximab (anti-CD80) (Ab177850) is more than 95% verified by HPLC.
Galiximab (anti-CD80) (Ab177850) - ELISA
Immobilized Recombinant Human CD80 Protein (rp189426) at 1.0 μg/mL can bind Galiximab (anti-CD80) (Ab177850) with the EC50 of 95.6 ng/mL.
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | Dec 20, 2023 | Ab177850 | |
| Certificate of Analysis | Dec 20, 2023 | Ab177850 |