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Galiximab (anti-CD80) - Primary antibody, specific to CD80, >95%, high purity, Human IgG1, INHIBITOR of T-lymphocyte activation antigen CD80 inhibitor, INHIBITOR of T-lymphocyte activation antigen CD80 inhibitor

    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Cynomolgus monkey,Human
  • Isotype: Human IgG1
  • Conjugation: Unconjugated
In stock
Item Number
Ab177850
Grouped product items
SKU Size
Availability
Price Qty
Ab177850-100μg
100μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$59.90
Ab177850-1mg
1mg
5
$279.90
Ab177850-5mg
5mg
1
$909.90
Ab177850-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,429.90

Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated

Basic Description

Product Name Galiximab (anti-CD80) - Primary antibody, specific to CD80, >95%, high purity, Human IgG1, INHIBITOR of T-lymphocyte activation antigen CD80 inhibitor
Synonyms Activation B7-1 antigen | B7 | BB1 | CTLA-4 counter-receptor B7.1
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Host species Human
Specificity CD80
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Action Type INHIBITOR
Mechanism of action INHIBITOR of T-lymphocyte activation antigen CD80 inhibitor
Product Description

Galiximab (anti-CD80) is a primatized immunoglobulin G1 (IgG1) lambda monoclonal antibody directed against the CD80 antigen. Galiximab (anti-CD80) has variable regions are primatized (cynomologous monkeys), and the constant regions are human. Galiximab (anti-CD80) can be used in research of B-cell lymphoma.

Product Properties

Isotype Human IgG1
Light Chain Type lambda
SDS-PAGE 28.8 kDa (Light Chain) & 51.6 kDa (Heavy Chain), under reducing conditions; 183.4 kDa, under non-reducing conditions.
Purification Method Protein A purified
Purity >95%
Shape Liquid
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
CAS 357613-77-5

Associated Targets(Human)

CD80 Tclin T-lymphocyte activation antigen CD80 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Galiximab (anti-CD80) (Ab177850) - Flow Cytometry
Flow Cytometry analysis of Raji cells labelling CD80 (red) with Galiximab (anti-CD80) (Ab177850). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

Galiximab (anti-CD80) (Ab177850) - SEC
The purity of Galiximab (anti-CD80) (Ab177850) is more than 95% verified by HPLC.

Galiximab (anti-CD80) (Ab177850) - ELISA
Immobilized Recombinant Human CD80 Protein (rp189426) at 1.0 μg/mL can bind Galiximab (anti-CD80) (Ab177850) with the EC50 of 95.6 ng/mL.

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

2 results found

Lot Number Certificate Type Date Item
ZJ23F1202072 Certificate of Analysis Dec 20, 2023 Ab177850
ZJ23F1202073 Certificate of Analysis Dec 20, 2023 Ab177850

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