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G 28UCM - ≥98%(HPLC), high purity , CAS No.1094451-90-7

COA

Grade & Purity:

≥98%(HPLC)

Cas Number: 1094451-90-7
Molecular Weight: 464.38
PubChem CID: 24896615

In stock

Item Number

G288005

Grouped product items
SKU	Size	Availability	Price
G288005-1mg	1mg	3	$23.90
G288005-5mg	5mg	3	$98.90
G288005-10mg	10mg	3	$167.90
G288005-25mg	25mg	3	$345.90
G288005-50mg	50mg	3	$543.90
G288005-100mg	100mg	2	$1,399.90
G288005-250mg	250mg	1	$2,799.90

FASN inhibitor

View related series

Anti-infection (2803) Antibiotic (1629) Bacterial (3013) Fatty Acid Synthase (FASN) (41) Lipid metabolism (1912) Metabolic Enzyme/Protease (4860)

Basic Description

Synonyms	3-(3,4,5-Trihydroxybenzoyloxy)naphthalen-1-yl 3,4,5-trihydroxybenzoate \| UCM05
Specifications & Purity	≥98%(HPLC)
Biochemical and Physiological Mechanisms	FASN inhibitor. Inhibits breast cancer cell proliferationin vitro(IC50values are 21 - 79μM), including cell lines resistant to anti-HER2 therapies. Blocks HER2 signaling and induces apoptosis. Inhibits growth of breast cancer xenografts in mice without ca
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Benzenoids
  - Class Benzene and substituted derivatives
    - Subclass Benzoic acids and derivatives
      - Level5 Hydroxybenzoic acid derivatives
        Level6 Gallic acid and derivatives
        Level7 Galloyl esters

Kingdom	Organic compounds
Superclass	Benzenoids
Class	Benzene and substituted derivatives
Subclass	Benzoic acids and derivatives
Intermediate Tree Nodes	Hydroxybenzoic acid derivatives - Gallic acid and derivatives
Direct Parent	Galloyl esters
Alternative Parents	p-Hydroxybenzoic acid esters m-Hydroxybenzoic acid esters Phenol esters Naphthalenes Pyrogallols and derivatives Benzoyl derivatives 1-hydroxy-4-unsubstituted benzenoids 1-hydroxy-2-unsubstituted benzenoids Carboxylic acid esters Polyols Organic oxides Hydrocarbon derivatives
Molecular Framework	Aromatic homopolycyclic compounds
Substituents	Galloyl ester - M-hydroxybenzoic acid ester - P-hydroxybenzoic acid ester - Benzoate ester - Phenol ester - Naphthalene - Benzenetriol - Pyrogallol derivative - Benzoyl - 1-hydroxy-4-unsubstituted benzenoid - 1-hydroxy-2-unsubstituted benzenoid - Phenol - Carboxylic acid ester - Carboxylic acid derivative - Polyol - Hydrocarbon derivative - Organic oxide - Organic oxygen compound - Organooxygen compound - Aromatic homopolycyclic compound
Description	This compound belongs to the class of organic compounds known as galloyl esters. These are organic compounds that contain an ester derivative of 3,4,5-trihydroxybenzoic acid.
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Associated Targets(Human)

FASN Tchem Fatty acid synthase (3390 Activities)

Discover Target: FASN

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

Streptococcus pneumoniae (31063 Activities)

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Pseudomonas aeruginosa (123386 Activities)

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Enterobacter cloacae (7976 Activities)

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Klebsiella pneumoniae (43867 Activities)

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Staphylococcus aureus (210822 Activities)

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Acinetobacter baumannii (41033 Activities)

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Escherichia coli (133304 Activities)

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Enterococcus faecium (13803 Activities)

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Bacillus subtilis (32866 Activities)

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Enterococcus faecalis (29875 Activities)

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Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

IUPAC Name	[4-(3,4,5-trihydroxybenzoyl)oxynaphthalen-2-yl] 3,4,5-trihydroxybenzoate
INCHI	InChI=1S/C24H16O10/c25-16-6-12(7-17(26)21(16)29)23(31)33-14-5-11-3-1-2-4-15(11)20(10-14)34-24(32)13-8-18(27)22(30)19(28)9-13/h1-10,25-30H
InChIKey	KJCWIWDPTNVWRX-UHFFFAOYSA-N
Smiles	C1=CC=C2C(=C1)C=C(C=C2OC(=O)C3=CC(=C(C(=C3)O)O)O)OC(=O)C4=CC(=C(C(=C4)O)O)O
Isomeric SMILES	C1=CC=C2C(=C1)C=C(C=C2OC(=O)C3=CC(=C(C(=C3)O)O)O)OC(=O)C4=CC(=C(C(=C4)O)O)O
Molecular Weight	464.38
Reaxy-Rn	18757096
Reaxys-RN_link_address	https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=18757096&ln=

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

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9 results found

Lot Number	Certificate Type	Date	Item
A2416433	Certificate of Analysis	Oct 31, 2022	G288005
A2416434	Certificate of Analysis	Oct 31, 2022	G288005
A2416435	Certificate of Analysis	Oct 31, 2022	G288005
A2416436	Certificate of Analysis	Oct 31, 2022	G288005
J2229183	Certificate of Analysis	Oct 24, 2022	G288005
J2229184	Certificate of Analysis	Oct 24, 2022	G288005
J2229186	Certificate of Analysis	Oct 24, 2022	G288005
J2229181	Certificate of Analysis	Oct 24, 2022	G288005
J2229182	Certificate of Analysis	Oct 24, 2022	G288005

Chemical and Physical Properties

Solubility	Solvent:DMSO, Max Conc. mg/mL: 46.44, Max Conc. mM: 100; Solvent:ethanol, Max Conc. mg/mL: 46.44, Max Conc. mM: 100
Molecular Weight	464.400 g/mol
XLogP3	3.900
Hydrogen Bond Donor Count	6
Hydrogen Bond Acceptor Count	10
Rotatable Bond Count	6
Exact Mass	464.074 Da
Monoisotopic Mass	464.074 Da
Topological Polar Surface Area	174.000 Å²
Heavy Atom Count	34
Formal Charge	0
Complexity	707.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

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G 28UCM - ≥98%(HPLC), high purity , CAS No.1094451-90-7

Basic Description

Taxonomic Classification

Associated Targets(Human)

Associated Targets(non-human)

Mechanisms of Action

Names and Identifiers

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

Chemical and Physical Properties

Solution Calculators

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

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