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Fondaparinux sodium - 98%, high purity , Antithrombin-III activator, CAS No.114870-03-0, Antithrombin-III activator

COA COA
In stock
Item Number
F302246
Grouped product items
SKU Size
Availability
 Price Qty
F302246-5mg
5mg
3
$69.90
F302246-10mg
10mg
2
$119.90
F302246-25mg
25mg
1
$281.90
F302246-50mg
50mg
1
$490.90
F302246-100mg
100mg
1
$699.90
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Amino Acid/Protein Metabolism (1836) Factor Xa (34) Metabolic Enzyme/Protease (4860) serpin family C member 1 Activator (4)

Basic Description

Synonyms FONDAPARINUX SODIUM [JAN] | GSK-576428 | IC-851589 | X0Q6N9USOZ | fondaparinux sodique | Xantidar | decasodium 6-[6-[2-carboxylato-4-hydroxy-6-[4-hydroxy-6-methoxy-5-(sulfonatoamino)-2-(sulfonatooxymethyl)tetrahydropyran-3-yl]oxy-5-sulfonatooxy-tetrahydro
Specifications & Purity Moligand™, ≥98%
Biochemical and Physiological Mechanisms Fondaparinux sodium is an antithrombotic anticoagulant, a Factor Xa inhibitor. Fondaparinux sodium is chemically related to low molecular weight heparins. Its pentasaccharide structure corresponds to the antithrombin III (ATIII) binding site of heparin. F
Storage Temp Store at -20°C,Argon charged
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Grade Moligand™
Action Type ACTIVATOR
Mechanism of action Antithrombin-III activator
Product Description

Fondaparinux sodium is an antithrombin-dependent factor Xa inhibitor.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
Superclass Organic oxygen compounds
Class Organooxygen compounds
Subclass Carbohydrates and carbohydrate conjugates
Intermediate Tree Nodes Oligosaccharides
Direct Parent Oligosaccharide sulfates
Alternative Parents Fatty acyl glycosides  O-glucuronides  O-glycosyl compounds  Alkyl sulfates  Dicarboxylic acids and derivatives  Sulfuric acid monoesters  Sulfuric acid monoamides  Oxanes  Pyrans  Secondary alcohols  Carboxylic acid salts  Oxacyclic compounds  Carboxylic acids  Acetals  Organic oxides  Hydrocarbon derivatives  Carbonyl compounds  Organic sodium salts  Organonitrogen compounds  Organopnictogen compounds  
Molecular Framework Aliphatic heteromonocyclic compounds
Substituents Oligosaccharide sulfate - Fatty acyl glycoside - 1-o-glucuronide - O-glucuronide - Glucuronic acid or derivatives - Glycosyl compound - O-glycosyl compound - Dicarboxylic acid or derivatives - Sulfuric acid monoamide - Oxane - Pyran - Sulfuric acid monoester - Sulfate-ester - Alkyl sulfate - Sulfuric acid ester - Fatty acyl - Organic sulfuric acid or derivatives - Carboxylic acid salt - Secondary alcohol - Organoheterocyclic compound - Acetal - Carboxylic acid - Carboxylic acid derivative - Oxacycle - Organic alkali metal salt - Organopnictogen compound - Organic nitrogen compound - Carbonyl group - Organic oxide - Hydrocarbon derivative - Organic salt - Organic sodium salt - Alcohol - Organonitrogen compound - Aliphatic heteromonocyclic compound
Description This compound belongs to the class of organic compounds known as oligosaccharide sulfates. These are carbohydrates containing between 3 and 9 sugar units, one of which bear one or more sulfate groups.
External Descriptors Not available

Associated Targets(Human)

SERPINC1 Tclin Antithrombin-III (1 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)
F10 Tclin Coagulation factor X (9693 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Homo sapiens (32628 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Associated Targets(non-human)

Rattus norvegicus (775804 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Plasma (328 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Names and Identifiers

Pubchem Sid 504759610
Pubchem Sid Url https://pubchem.ncbi.nlm.nih.gov/substance/504759610
IUPAC Name decasodium;(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5R,6R)-6-[(2R,3S,4S,5R,6R)-2-carboxylato-4-hydroxy-6-[(2R,3S,4R,5R,6S)-4-hydroxy-6-methoxy-5-(sulfonatoamino)-2-(sulfonatooxymethyl)oxan-3-yl]oxy-5-sulfonatooxyoxan-3-yl]oxy-5-(sulfonatoamino)-4-sulfonatooxy-2-(sulfonatooxymethyl)oxan-3-yl]oxy-3-[(2R,3R,4R,5S,6R)-4,5-dihydroxy-3-(sulfonatoamino)-6-(sulfonatooxymethyl)oxan-2-yl]oxy-4,5-dihydroxyoxane-2-carboxylate
INCHI InChI=1S/C31H53N3O49S8.10Na/c1-69-27-9(33-85(48,49)50)13(37)17(6(74-27)3-71-88(57,58)59)76-31-22(83-91(66,67)68)16(40)21(24(81-31)26(43)44)79-29-10(34-86(51,52)53)19(82-90(63,64)65)18(7(75-29)4-72-89(60,61)62)77-30-15(39)14(38)20(23(80-30)25(41)42)78-28-8(32-84(45,46)47)12(36)11(35)5(73-28)2-70-87(54,55)56;;;;;;;;;;/h5-24,27-40H,2-4H2,1H3,(H,41,42)(H,43,44)(H,45,46,47)(H,48,49,50)(H,51,52,53)(H,54,55,56)(H,57,58,59)(H,60,61,62)(H,63,64,65)(H,66,67,68);;;;;;;;;;/q;10*+1/p-10/t5-,6-,7-,8-,9-,10-,11-,12-,13-,14-,15-,16+,17-,18-,19-,20+,21+,22-,23+,24-,27+,28-,29-,30-,31-;;;;;;;;;;/m1........../s1
InChIKey XEKSTYNIJLDDAZ-JASSWCPGSA-D
Smiles COC1C(C(C(C(O1)COS(=O)(=O)[O-])OC2C(C(C(C(O2)C(=O)[O-])OC3C(C(C(C(O3)COS(=O)(=O)[O-])OC4C(C(C(C(O4)C(=O)[O-])OC5C(C(C(C(O5)COS(=O)(=O)[O-])O)O)NS(=O)(=O)[O-])O)O)OS(=O)(=O)[O-])NS(=O)(=O)[O-])O)OS(=O)(=O)[O-])O)NS(=O)(=O)[O-].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+]
Isomeric SMILES CO[C@@H]1[C@@H]([C@H]([C@@H]([C@H](O1)COS(=O)(=O)[O-])O[C@H]2[C@@H]([C@H]([C@@H]([C@@H](O2)C(=O)[O-])O[C@@H]3[C@@H]([C@H]([C@@H]([C@H](O3)COS(=O)(=O)[O-])O[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)C(=O)[O-])O[C@@H]5[C@@H]([C@H]([C@@H]([C@H](O5)COS(=O)(=O)[O-])O)O)NS(=O)(=O)[O-])O)O)OS(=O)(=O)[O-])NS(=O)(=O)[O-])O)OS(=O)(=O)[O-])O)NS(=O)(=O)[O-].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+]
PubChem CID 636380
Molecular Weight 1728.08

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

11 results found

Lot Number Certificate Type Date Item
F2513397 Certificate of Analysis May 30, 2025 F302246
F2513410 Certificate of Analysis May 30, 2025 F302246
F2513413 Certificate of Analysis May 30, 2025 F302246
F2513414 Certificate of Analysis May 30, 2025 F302246
F2513415 Certificate of Analysis May 30, 2025 F302246
K2202681 Certificate of Analysis Sep 06, 2022 F302246
K2202680 Certificate of Analysis Sep 06, 2022 F302246
K2202682 Certificate of Analysis Sep 06, 2022 F302246
K2202732 Certificate of Analysis Sep 06, 2022 F302246
K2202679 Certificate of Analysis Sep 06, 2022 F302246
K2411030 Certificate of Analysis Sep 06, 2022 F302246

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Chemical and Physical Properties

Sensitivity Moisture sensitive.
Molecular Weight 1728.100 g/mol
XLogP3
Hydrogen Bond Donor Count 9
Hydrogen Bond Acceptor Count 52
Rotatable Bond Count 20
Exact Mass 1726.77 Da
Monoisotopic Mass 1726.77 Da
Topological Polar Surface Area 901.000 Ų
Heavy Atom Count 101
Formal Charge 0
Complexity 3330.000
Isotope Atom Count 0
Defined Atom Stereocenter Count 25
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
The total count of all stereochemical bonds 0
Covalently-Bonded Unit Count 11

Solution Calculators

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