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Fluticasone propionate-d5 , CAS No.1093258-28-6

COA

Grade & Purity:

≥92%,≥95 atom% D

Cas Number: 1093258-28-6
Molecular Weight: 505.61
PubChem CID: 91820603

In stock

Item Number

F336070

Grouped product items
SKU	Size	Availability	Price	Qty
F336070-1mg	1mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$839.90

a pentadeuterated form of fluticasone propionate

View related series

Anti-infection (2803) Enterovirus (39) Glucocorticoid Receptor (103) Immunology/Inflammation (1929) Metabolite (5307) Stable isotope (189) Virus (1811) Vitamin D Related/Nuclear Receptor (907)

Basic Description

Synonyms	[(6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-difluoro-17-(fluoromethylsulfanylcarbonyl)-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] 2,2,3,3,3-pentadeuteriopropanoate \| DTXSID501101416 \| SS-4490 \| AKOS025311
Specifications & Purity	≥92%,≥95atom%D
Storage Temp	Store at 2-8°C
Shipped In	Wet ice This product requires cold chain shipping. Ground and other economy services are not available.
Product Description	Fluticasone propionate-d5 is the labeled form of fluticasone propionate . Fluticasone propionate is a high affinity, selective glucocorticoid receptor (GR) agonist (K\|d\|= 0.5 nM). Fluticasone propionate potently stimulates glucocorticoid receptor-mediated transactivation of gene expression and enhances human eosinophil apoptosis (EC\|50\|= 3.7 nM)\|in vitro\|. Fluticasone propionate is a lipophilic anti-inflammatory agent derived from flumethasone .

Names and Identifiers

IUPAC Name	[(6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-difluoro-17-(fluoromethylsulfanylcarbonyl)-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] 2,2,3,3,3-pentadeuteriopropanoate
INCHI	InChI=1S/C25H31F3O5S/c1-5-20(31)33-25(21(32)34-12-26)13(2)8-15-16-10-18(27)17-9-14(29)6-7-22(17,3)24(16,28)19(30)11-23(15,25)4/h6-7,9,13,15-16,18-19,30H,5,8,10-12H2,1-4H3/t13-,15+,16+,18+,19+,22+,23+,24+,25+/m1/s1/i1D3,5D2
InChIKey	WMWTYOKRWGGJOA-AMTWIDTLSA-N
Smiles	CCC(=O)OC1(C(CC2C1(CC(C3(C2CC(C4=CC(=O)C=CC43C)F)F)O)C)C)C(=O)SCF
Isomeric SMILES	[2H]C([2H])([2H])C([2H])([2H])C(=O)O[C@@]1([C@@H](C[C@@H]2[C@@]1(C[C@@H]([C@]3([C@H]2C[C@@H](C4=CC(=O)C=C[C@@]43C)F)F)O)C)C)C(=O)SCF
Alternate CAS	80474-14-2（unlabelled）
Molecular Weight	505.61
Reaxy-Rn	30890347
Reaxys-RN_link_address	https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=30890347&ln=

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Chemical and Physical Properties

Solubility	Soluble in chloroform, ethyl acetate, and dichloromethane(Sparingly).
Refractive Index	n20D1.56 (Predicted)
Boil Point(°C)	568.3° C
Melt Point(°C)	265-267° C (dec.)

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