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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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F650074-5mg
|
5mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$420.90
|
|
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F650074-10mg
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10mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$700.90
|
|
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F650074-25mg
|
25mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$1,400.90
|
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| Specifications & Purity | ≥98% |
|---|---|
| Biochemical and Physiological Mechanisms | Fluoroethylnormemantine hydrochloride, a derivative of Memantine, is an antagonist of the N-methyl-D-aspartate (NMDA) receptor . [ 18 F]-Fluoroethylnormemantine hydrochloride can be used as a positron emission tomography (PET) tracer. Fluoroethylnormemant |
| Storage Temp | Store at -20°C,Desiccated |
| Shipped In |
Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available. |
| Product Description |
Fluoroethylnormemantine hydrochloride, a derivative of Memantine, is an antagonist of the N-methyl-D-aspartate (NMDA) receptor . [ 18 F]-Fluoroethylnormemantine hydrochloride can be used as a positron emission tomography (PET) tracer. Fluoroethylnormemantine hydrochloride exhibits anti-amnesic, neuroprotective, antidepressant-like and fear-attenuating effects In Vivo Fluoroethylnormemantine (0.1-10 mg/kg; a single i.p.) shows anti-amnesic effects on Aβ 25-35 -induced learning impairments in mice . Fluoroethylnormemantine (0.1-10 mg/kg; i.p. once daily for 7 days) attenuates Aβ 25-35 -induced behavioral deficits, neuroinflammation, oxidative stress, apoptosis, and cell loss in mice . Fluoroethylnormemantine (1-20 mg/kg; a single injection) decreases behavioral despair in the forced swim test (FST) and reduces fear behavior in the cued fear conditioning (FC) and extinction training in rats. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: Male Swiss CD-1 mice (7-9 weeks) were injected with Aβ 25-35 Dosage: 0.1, 0.3, 1, 3, 10 mg/kg Administration: I.p. 30 minutes before the behavioral tests Result: Attenuated Aβ 25-35 -induced spontaneous alternation deficit, passive avoidance deficit, and novel object exploration deficit. Form:Solid IC50& Target:NMDA receptor |
| Smiles | [H]Cl.FCC[C@](C[C@H](C1)C2)(C[C@@H]1C3)C[C@]23N |
|---|---|
| Molecular Weight | 233.75 |