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Fluorescein - Analytical Reagent,90%, high purity , CAS No.2321-07-5

    Grade & Purity:
  • AR
  • ≥90%
In stock
Item Number
F100007
Grouped product items
SKU Size
Availability
Price Qty
F100007-25g
25g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$12.90
F100007-100g
100g
3
$37.90
F100007-250g
250g
2
$85.90
F100007-500g
500g
1
$149.90

Basic Description

Synonyms 3',6'-Dihydroxyfluoran | C.I. Solvent Yellow 94 | Fluoresceine | Resorcinolphthalein | Solvent Yellow 94 | 3',6'-Dihydroxy-3H-spiro[isobenzofuran-1,9'-xanthen]-3-one | D&C Yellow No. 7 | fluorescein | Japan Yellow 201 | Yellow fluorescein | D and C Yellow
Specifications & Purity AR, ≥90%
Shipped In Normal
Grade AR

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
Superclass Organoheterocyclic compounds
Class Benzopyrans
Subclass 1-benzopyrans
Intermediate Tree Nodes Dibenzopyrans
Direct Parent Xanthenes
Alternative Parents Diarylethers  Phthalides  Benzofuranones  Isobenzofurans  1-hydroxy-2-unsubstituted benzenoids  Lactones  Carboxylic acid esters  Oxacyclic compounds  Monocarboxylic acids and derivatives  Organic oxides  Hydrocarbon derivatives  
Molecular Framework Aromatic heteropolycyclic compounds
Substituents Xanthene - Diaryl ether - Benzofuranone - Phthalide - Isobenzofuranone - Isobenzofuran - Isocoumaran - 1-hydroxy-2-unsubstituted benzenoid - Benzenoid - Lactone - Carboxylic acid ester - Oxacycle - Monocarboxylic acid or derivatives - Ether - Carboxylic acid derivative - Hydrocarbon derivative - Organic oxygen compound - Organooxygen compound - Organic oxide - Aromatic heteropolycyclic compound
Description This compound belongs to the class of organic compounds known as xanthenes. These are polycyclic aromatic compounds containing a xanthene moiety, which consists of two benzene rings joined to each other by a pyran ring.
External Descriptors xanthene dye - polyphenol - gamma-lactone

Associated Targets(Human)

FTO Tchem Alpha-ketoglutarate-dependent dioxygenase FTO (473 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ALKBH5 Tchem RNA demethylase ALKBH5 (134 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Associated Targets(non-human)

Hdac6 Histone deacetylase 6 (222 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
surA Chaperone SurA (18 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
SARS-CoV-2 (38078 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Names and Identifiers

IUPAC Name 3',6'-dihydroxyspiro[2-benzofuran-3,9'-xanthene]-1-one
INCHI InChI=1S/C20H12O5/c21-11-5-7-15-17(9-11)24-18-10-12(22)6-8-16(18)20(15)14-4-2-1-3-13(14)19(23)25-20/h1-10,21-22H
InChIKey GNBHRKFJIUUOQI-UHFFFAOYSA-N
Smiles C1=CC=C2C(=C1)C(=O)OC23C4=C(C=C(C=C4)O)OC5=C3C=CC(=C5)O
Isomeric SMILES C1=CC=C2C(=C1)C(=O)OC23C4=C(C=C(C=C4)O)OC5=C3C=CC(=C5)O
Molecular Weight 332.31
Reaxy-Rn 94324
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=94324&ln=

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

16 results found

Lot Number Certificate Type Date Item
G2504351 Certificate of Analysis Jun 23, 2025 F100007
G2504377 Certificate of Analysis Jun 23, 2025 F100007
G2504380 Certificate of Analysis Jun 23, 2025 F100007
G2504381 Certificate of Analysis Jun 23, 2025 F100007
H2126274 Certificate of Analysis Jun 09, 2025 F100007
K2429321 Certificate of Analysis Nov 20, 2024 F100007
K2429319 Certificate of Analysis Nov 20, 2024 F100007
K2429320 Certificate of Analysis Nov 20, 2024 F100007
H2429016 Certificate of Analysis Sep 04, 2024 F100007
D23261066 Certificate of Analysis Dec 09, 2022 F100007
D23261059 Certificate of Analysis Dec 09, 2022 F100007
D2326924 Certificate of Analysis Dec 09, 2022 F100007
G2201325 Certificate of Analysis Jun 05, 2022 F100007
G2201326 Certificate of Analysis Jun 05, 2022 F100007
G2201327 Certificate of Analysis Jun 05, 2022 F100007
H2126273 Certificate of Analysis Jul 29, 2021 F100007

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Chemical and Physical Properties

Solubility Slightly soluble in water and alcohol.
Sensitivity Moisture sensitive.
Melt Point(°C) 314-316°C
Molecular Weight 332.300 g/mol
XLogP3 3.400
Hydrogen Bond Donor Count 2
Hydrogen Bond Acceptor Count 5
Rotatable Bond Count 0
Exact Mass 332.068 Da
Monoisotopic Mass 332.068 Da
Topological Polar Surface Area 76.000 Ų
Heavy Atom Count 25
Formal Charge 0
Complexity 522.000
Isotope Atom Count 0
Defined Atom Stereocenter Count 0
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
The total count of all stereochemical bonds 0
Covalently-Bonded Unit Count 1

Citations of This Product

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71. Jixiang Wang, Rujia Cheng, Yunyun Wang, Lin Sun, Li Chen, Xiaohui Dai, Jianming Pan, Guoqing Pan, Yongsheng Yan.  (2018)  Surface-imprinted fluorescence microspheres as ultrasensitive sensor for rapid and effective detection of tetracycline in real biological samples.  SENSORS AND ACTUATORS B-CHEMICAL,  263  (533). 
72. Dongdong Wang, Feifei Sun, Chunbo Lu, Peng Chen, Zhaojie Wang, Yuanhao Qiu, Haibo Mu, Zehong Miao, Jinyou Duan.  (2018)  Inulin based glutathione-responsive delivery system for colon cancer treatment.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,  111  (1264). 
73. Junyu Chen, Meiying Liu, Qiang Huang, Long Huang, Hongye Huang, Fengjie Deng, Yuanqing Wen, Jianwen Tian, Xiaoyong Zhang, Yen Wei.  (2018)  Facile preparation of fluorescent nanodiamond-based polymer composites through a metal-free photo-initiated RAFT process and their cellular imaging.  CHEMICAL ENGINEERING JOURNAL,  337  (82). 
74. Lei Han, Shi Gang Liu, Jiang Xue Dong, Jia Yu Liang, Ling Jie Li, Nian Bing Li, Hong Qun Luo.  (2017)  Facile synthesis of multicolor photoluminescent polymer carbon dots with surface-state energy gap-controlled emission.  Journal of Materials Chemistry C,  (41): (10785-10793). 
75. Guli Li, Bei Zhang, Xinbo Song, Ying Xia, Haibo Yu, Xinfu Zhang, Yi Xiao, Youtao Song.  (2017)  Ratiometric imaging of mitochondrial pH in living cells with a colorimetric fluorescent probe based on fluorescein derivative.  SENSORS AND ACTUATORS B-CHEMICAL,  253  (58). 
76. Yusha Feng, Ziyu Kuai, Yan Song, Jing Guo, Qingbiao Yang, Yaming Shan, Yaoxian Li.  (2017)  A novel “turn-on” thiooxofluorescein-based colorimetric and fluorescent sensor for Hg2+ and its application in living cells.  TALANTA,  170  (103). 
77. Lingjie Hou, Jia Feng, Yubin Wang, Chuan Dong, Shaomin Shuang, Yu Wang.  (2017)  Single fluorescein-based probe for selective colorimetric and fluorometric dual sensing of Al3+ and Cu2+.  SENSORS AND ACTUATORS B-CHEMICAL,  247  (451). 
78. Huang Zengfang, Zhang Xiqi, Zhang Xiaoyong, Wang Shiqi, Yang Bin, Wang Ke, Yuan Jinying, Tao Lei, Wei Yen.  (2017)  Synthesis of amphiphilic fluorescent copolymers with smart pH sensitivity via RAFT polymerization and their application in cell imaging.  POLYMER BULLETIN,  74  (11): (4525-4536). 
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80. Huimin He, Xiaodong Cao, Hua Dong, Ting Ma, Gregory F. Payne.  (2017)  Reversible Programing of Soft Matter with Reconfigurable Mechanical Properties.  ADVANCED FUNCTIONAL MATERIALS,  27  (13): (1605665). 
81. Shimo Kang, Xin Zhao, Lu Yue, Ling Liu.  (2016)  Main anthraquinone components in Aloe vera and their inhibitory effects on the formation of advanced glycation end-products.  JOURNAL OF FOOD PROCESSING AND PRESERVATION,  41  (5): (e13160). 
82. Xu Wenchao, Hou Zining, Liu Zhenhua, Wu Zhigang.  (2016)  Viscosity-difference-induced asymmetric selective focusing for large stroke particle separation.  Microfluidics and Nanofluidics,  20  (9): (1-13). 
83. Zhang Zhen, He Caian, Zhu Ruixue, Shen Jing, Yu Yueli, Peng Qiang, Gao Jinfeng, Li Yunlong, Wang Min.  (2016)  Seed Oils of Five Black Tartary Buckwheat Cultivars with Biochemical Characterization and Antioxidant Properties.  JOURNAL OF THE AMERICAN OIL CHEMISTS SOCIETY,  93  (8): (1127-1136). 
84. Xin Wu, Xiaojuan Gong, Wenjuan Dong, Jun Ma, Jianbin Chao, Chenzhong Li, Li Wang, Chuan Dong.  (2016)  A novel fluorescein-based colorimetric probe for Cu2+ detection.  RSC Advances,  (64): (59677-59683). 
85. Weiping Ding, Xingxia Zhu, Lili Zou, Jing Liu, Dongmin Wang, Cheng Liang, Chengpan Li, Liqun He.  (2016)  Estimation of the porosity of a chitosan–carbon nanoparticle membrane fabricated on a chip: A solute transport-based study.  INTERNATIONAL JOURNAL OF HEAT AND MASS TRANSFER,  99  (822). 
86. Chen Donghua, Peng Rulin, Zhou Hong, Liu Hui.  (2016)  Sensitive determination of 4-nitrophenol based on its enhancement of a peroxyoxalate chemiluminescence system containing graphene oxide quantum dots and fluorescein.  MICROCHIMICA ACTA,  183  (5): (1699-1704). 
87. Hui Sun, Jia-Ping Lai, Dong-Sheng Lin, Xue-Xia Huang, Yue Zuo, Yun-Ling Li.  (2016)  A novel fluorescent multi-functional monomer for preparation of silver ion-imprinted fluorescent on–off chemosensor.  SENSORS AND ACTUATORS B-CHEMICAL,  224  (485). 
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