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| SKU | Size | Availability |
Price | Qty |
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F407755-1ml
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1ml |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$346.90
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Glucocorticoid Receptor Agonists
| Synonyms | Flucort-N | (6α,11β,16α)-6,9-difluoro-11,21-dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]-pregna-1,4-diene-3,20-dione |
|---|---|
| Specifications & Purity | Moligand™, 10mM in DMSO |
| Biochemical and Physiological Mechanisms | Fluocinolone Acetonide (Flucort-N) is a corticosteroid that binds to the cytosolic glucocorticoid receptor. |
| Storage Temp | Store at -80°C |
| Shipped In |
Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available. |
| Grade | Moligand™ |
| Action Type | AGONIST |
| Mechanism of action | Glucocorticoid receptor agonist |
| Product Description |
Information Fluocinolone Acetonide Fluocinolone Acetonide (Flucort-N) is a corticosteroid that binds to the cytosolic glucocorticoid receptor. In vivo
cell lines: Concentrations: Incubation Time: Powder Purity:≥99% |
| ALogP | 0.995 |
|---|---|
| hba_count | 4 |
| HBD Count | 2 |
| Rotatable Bond | 2 |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Smiles | CC1(C)OC2CC3C4CC(F)C5=CC(=O)C=CC5(C)C4(F)C(O)CC3(C)C2(O1)C(=O)CO |
|---|---|
| Molecular Weight | 452.4999 |
| Reaxy-Rn | 37811598 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=37811598&ln= |
| DMSO(mg / mL) Max Solubility | 90 |
|---|---|
| DMSO(mM) Max Solubility | 198.9 |
| Water(mg / mL) Max Solubility | <1 |
| 1. Yangjie LI, Jiaying HUANG, Jihui FANG, Zhiye HUANG. (2022) [Fast screening and confirmation of 73 common prohibited compounds in cosmetics by ultra performance liquid chromatography-quadrupole-time-of-flight high resolution mass spectrometry].. Chinese Journal of Chromatography, 40 (5): (433-442). |
| 2. Youfang Huang, Yanyun Li, Qing Luo, Xiaojia Huang. (2021) One-step preparation of functional groups-rich graphene oxide and carbon nanotubes nanocomposite for efficient magnetic solid phase extraction of glucocorticoids in environmental waters. CHEMICAL ENGINEERING JOURNAL, 406 (126785). |