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Basic Description

Synonyms Fluorescein isothiocyanate–dextran
Storage Temp Store at 2-8°C,Protected from light,Argon charged
Shipped In
Wet ice
This product requires cold chain shipping. Ground and other economy services are not available.
Product Description

Product Describtion:

FITC-dextrans are synthesised by coupling fluoresceinyl isothiocyanate (5-isomer) to selected dextran fractions. All batches are checked for molecular weight, degree of substitution, loss on drying and free FITC. Aladdin produce FITC-dextrans from 4 kDa to 2000 kDa. FITC-dextrans are supplied as a yellow to orange powder.Dextran is a branched polysaccharide elaborated by the bacteria Leuconostoc mesenteroides B512F. Dextran is essentially a linear glucose chain linked by α-D-(1 – 6) linkages. The degree of branching is about 5 %. The fluorescein moiety is attached by a stable thiocarbamoyl linkage and the labelling procedure does not lead to any depolymerization of the dextran. FITC-dextrans have from 0.001-0.020 mol FITC per glucose unit. These low levels of substitution confer minimal charges to dextran, which is an essential requirement for permeability studies.FITC-dextran has an excitation maximum of 493 nm and an emission maximum of 518 nm. Maximal intensity is observed at pH >8.dextran is mainly used for studying permeability and microcirculation. It can also be used as a molecular size marker, for studies of drug delivery and more.If you need larger quantities please contact us for a bulk quotation.

Product specifications and parameters:
SKU NAME Molecular Weight
F491425-4 kDa FITC-dextran 4 kDa
F491425-10 kDa FITC-dextran 10 kDa
F491425-20 kDa FITC-dextran 20 kDa
F491425-40 kDa FITC-dextran 40 kDa
F491425-70 kDa FITC-dextran 70 kDa
F491425-110 kDa FITC-dextran 110 kDa
F491425-150 kDa FITC-dextran 150 kDa
F491425-500 kDa FITC-dextran 500 kDa
F491425-2000 kDa FITC-dextran 2000 kDa
F491425-250 kDa FITC-dextran 250 kDa


Product Properties

Excitation and Emision Ranges 493 nm and 518 nm

Names and Identifiers

WGK Germany 3

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

68 results found

Lot Number Certificate Type Date Item
E2520624 Certificate of Analysis Mar 25, 2025 F491425
C2518767 Certificate of Analysis Mar 08, 2025 F491425
C2518790 Certificate of Analysis Mar 08, 2025 F491425
C2518791 Certificate of Analysis Mar 08, 2025 F491425
J2431164 Certificate of Analysis Nov 05, 2024 F491425
I2424346 Certificate of Analysis Sep 10, 2024 F491425
I2424347 Certificate of Analysis Sep 10, 2024 F491425
I2424345 Certificate of Analysis Sep 10, 2024 F491425
C2408184 Certificate of Analysis Jan 25, 2024 F491425
H2421117 Certificate of Analysis Jan 25, 2024 F491425
A2304027 Certificate of Analysis Dec 19, 2023 F491425
A2404032 Certificate of Analysis Dec 19, 2023 F491425
A2404460 Certificate of Analysis Dec 19, 2023 F491425
I2304141 Certificate of Analysis Sep 06, 2023 F491425
F2313379 Certificate of Analysis Jun 30, 2023 F491425
F2313375 Certificate of Analysis Jun 26, 2023 F491425
F2313398 Certificate of Analysis Jun 26, 2023 F491425
F2313388 Certificate of Analysis Jun 26, 2023 F491425
F2313378 Certificate of Analysis Jun 26, 2023 F491425
F2313431 Certificate of Analysis Jun 26, 2023 F491425
F2313380 Certificate of Analysis Jun 26, 2023 F491425
F2313012 Certificate of Analysis Jun 26, 2023 F491425
F2313392 Certificate of Analysis Jun 21, 2023 F491425
F2313385 Certificate of Analysis Jun 21, 2023 F491425
F2313382 Certificate of Analysis Jun 21, 2023 F491425
F2313013 Certificate of Analysis Jun 17, 2023 F491425
E2318146 Certificate of Analysis May 27, 2023 F491425
G2422475 Certificate of Analysis May 27, 2023 F491425
E2318133 Certificate of Analysis May 27, 2023 F491425
E2318159 Certificate of Analysis May 27, 2023 F491425
E2318134 Certificate of Analysis May 27, 2023 F491425
E2318152 Certificate of Analysis May 27, 2023 F491425
F2507113 Certificate of Analysis May 27, 2023 F491425
E2527067 Certificate of Analysis May 27, 2023 F491425
E2318126 Certificate of Analysis May 27, 2023 F491425
L2313518 Certificate of Analysis May 27, 2023 F491425
G2504078 Certificate of Analysis May 27, 2023 F491425
E2318144 Certificate of Analysis May 27, 2023 F491425
F2507118 Certificate of Analysis May 27, 2023 F491425
E2318127 Certificate of Analysis May 26, 2023 F491425
E2318147 Certificate of Analysis May 26, 2023 F491425
C2508182 Certificate of Analysis May 26, 2023 F491425
F2507111 Certificate of Analysis May 26, 2023 F491425
E2318130 Certificate of Analysis May 26, 2023 F491425
E2318135 Certificate of Analysis May 25, 2023 F491425
E2318150 Certificate of Analysis May 25, 2023 F491425
E2318132 Certificate of Analysis May 25, 2023 F491425
E2318140 Certificate of Analysis May 25, 2023 F491425
E2318170 Certificate of Analysis May 25, 2023 F491425
E2318143 Certificate of Analysis May 25, 2023 F491425
E2318131 Certificate of Analysis May 25, 2023 F491425
E2318164 Certificate of Analysis May 25, 2023 F491425
E2318123 Certificate of Analysis May 25, 2023 F491425
E2318149 Certificate of Analysis May 25, 2023 F491425
E2318138 Certificate of Analysis May 25, 2023 F491425
E2318137 Certificate of Analysis May 24, 2023 F491425
D2423027 Certificate of Analysis May 24, 2023 F491425
E2318139 Certificate of Analysis May 24, 2023 F491425
E2318145 Certificate of Analysis May 24, 2023 F491425
E2318141 Certificate of Analysis May 24, 2023 F491425
B2419113 Certificate of Analysis May 24, 2023 F491425
E2318163 Certificate of Analysis May 24, 2023 F491425
E2414037 Certificate of Analysis May 24, 2023 F491425
A2210003 Certificate of Analysis May 24, 2023 F491425
E2318171 Certificate of Analysis May 24, 2023 F491425
A2211678 Certificate of Analysis May 24, 2023 F491425
G2417050 Certificate of Analysis May 24, 2023 F491425
E2318148 Certificate of Analysis May 24, 2023 F491425

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Chemical and Physical Properties

Sensitivity Light sensitive

Citations of This Product

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3. Lingna Xie, Guangrong Liu, Zebin Huang, Zhenyuan Zhu, Kaiye Yang, Yiheng Liang, Yani Xu, Lanyue Zhang, Zhiyun Du.  (2023)  Tremella fuciformis Polysaccharide Induces Apoptosis of B16 Melanoma Cells via Promoting the M1 Polarization of Macrophages.  MOLECULES,  28  (10): (4018). 
4. Wen Li, Jin-Xuan Fan, Ji-Yan Qiao, Qi-Wen Chen, Yun-Xia Sun, Xian-Zheng Zhang.  (2023)  Colon-targeted bacterial hydrogel for tumor vascular normalization and improved chemotherapy.  JOURNAL OF CONTROLLED RELEASE,  356  (59). 
5. Ningbo Qin, Hongxu Liu, Yu Cao, Zhen Wang, Xiaomeng Ren, Xiaodong Xia.  (2023)  Polysaccharides from the seeds of Gleditsia sinensis Lam. attenuate DSS-induced colitis in mice via improving gut barrier homeostasis and alleviating gut microbiota dybiosis.  Food & Function,  14  (1): (122-132). 
6. Sijie Zhou, Dejun Yang, Dong Yang, Yan Guo, Ronggui Hu, Yuan Li, Xingjie Zan, Xingxing Zhang.  (2022)  Injectable, Self-Healing and Multiple Responsive Histamine Modified Hyaluronic Acid Hydrogels with Potentialities in Drug Delivery, Antibacterial and Tissue Engineering.  MACROMOLECULAR RAPID COMMUNICATIONS,  44  (3): (2200674). 
7. Shufang Chen, Zhongyue Ren, Yalan Huo, Wanyu Yang, Lingling Peng, Huihui Lv, Lijuan Nie, Hua Wei, Cuixiang Wan.  (2022)  Targeting the gut microbiota to investigate the mechanism of Lactiplantibacillus plantarum 1201 in negating colitis aggravated by a high-salt diet.  FOOD RESEARCH INTERNATIONAL,  162  (112010). 
8. Zheng Cao, Jinsong Gao, Wanyue Huang, Juli Yan, Anshan Shan, Xiang Gao.  (2022)  Curcumin mitigates deoxynivalenol-induced intestinal epithelial barrier disruption by regulating Nrf2/p53 and NF-κB/MLCK signaling in mice.  FOOD AND CHEMICAL TOXICOLOGY,  167  (113281). 
9. Zebin Huang, Lingna Xie, Yongyu Xu, Kai Zhao, Xuetong Li, Jiaben Zhong, Yujing Lu, Xuetao Xu, Susan Goodin, Kun Zhang, Lanyue Zhang, Chunlian Li, Xi Zheng.  (2021)  Essential Oils from Zingiber striolatum Diels Attenuate Inflammatory Response and Oxidative Stress through Regulation of MAPK and NF-κB Signaling Pathways.  Antioxidants,  10  (12): (2019). 
10. Yue Bei, Gao Ruiyang, Lv Cheng, Yu Zhilun, Wang Hao, Geng Xiaolong, Wang Zhengtao, Dou Wei.  (2021)  Berberine Improves Irinotecan-Induced Intestinal Mucositis Without Impairing the Anti-colorectal Cancer Efficacy of Irinotecan by Inhibiting Bacterial β-glucuronidase.  Frontiers in Pharmacology,  12  (2880). 
11. Wen Lijuan, Peng Yu, Wang Kai, Huang Zhihua, He Shiying, Xiong Ruiwen, Wu Longping, Zhang Fengtian, Hu Fuqiang.  (2022)  Regulation of pathological BBB restoration via nanostructured ROS-responsive glycolipid-like copolymer entrapping siVEGF for glioblastoma targeted therapeutics.  Nano Research,  15  (2): (1455-1465). 
12. Zheng Di-Wei, Hong Sheng, Zhang Qiu-Ling, Dong Xue, Pan Pei, Song Wen-Fang, Song Wen, Cheng Si-Xue, Zhang Xian-Zheng.  (2020)  Controllable gelation of artificial extracellular matrix for altering mass transport and improving cancer therapies.  Nature Communications,  11  (1): (1-15). 
13. Min Fu, Xiao-han Jiang, Min Wang, Zhi-ning Fan, Yu-lin Gu, Rui-han Zou, Li-li Zhao, Li Liu.  (2024)  Catalase catalyzed tannic acid-Fe3+ network coating: A theranostic strategy for intestinal barrier restoration.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,  274  (133304). 
14. Tong Liu, Siqing Fan, Pengfei Meng, Mingxia Ma, Yanxin Wang, Jiaojiao Han, Yufei Wu, Xiao Li, Xiurong Su, Chenyang Lu.  (2024)  Dietary Dihydroquercetin Alleviated Colitis via the Short-Chain Fatty Acids/miR-10a-5p/PI3K-Akt Signaling Pathway.  JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,  72  (42): (23211-23223). 
15. Baihao You, Chia-Hung Chen.  (2024)  Fluidic Membrane-Bound Protocells Enabling Versatile Assembly of Functional Nanomaterials for Biomedical Applications.  ACS Nano,  18  (49): (33545-33554). 
16. Qiaozhen Liu, Songyi Lin, Kexin Liu, Shuqi Jia, Shuya Wang, Na Sun.  (2024)  Fucoidan-Mediated Covalent Modification Mitigates Allergenicity of Shrimp (Penaeus vannamei) in Mice via Enhanced Intestinal Barrier Function and Antigen Presentation Suppression.  JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,  73  (1): (811-821). 
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18. Li-Li Zhang, Jia-Ying Xu, Yifei Xing, Pengcheng Wu, Yi-Wen Jin, Wei Wei, Lin Zhao, Jing Yang, Guo-Chong Chen, Li-Qiang Qin.  (2024)  Lactobacillus rhamnosus GG alleviates radiation-induced intestinal injury by modulating intestinal immunity and remodeling gut microbiota.  MICROBIOLOGICAL RESEARCH,  286  (127821). 
19. Jian Liu, Junbo Li, Yan Huang, Tong Li, Cheng Xu, Zhengyu Tao, Wei Ji, Xin Huang.  (2025)  Liquid-to-gel transitions of phase-separated coacervate microdroplets enabled by endogenous enzymatic catalysis.  JOURNAL OF COLLOID AND INTERFACE SCIENCE,  692  (137486). 
20. Xiaoying Zhang, Shiyu Wang, Jinyu Xie, Jinyu Wang, Yaru Gu, Bo Wu, Yixin Zhang, Tingxu Yan, Ying Jia.  (2025)  Multi-platform analysis revealed the substance basis and mechanism of Wei-Tong-Xin in ameliorating ENS dysfunction for dyspepsia treatment.  JOURNAL OF ETHNOPHARMACOLOGY,  337  (118875). 
21. Yingqi Wang, Shen Zhao, Nengyi Ni, Hongyu Chen, Wenjian Zhao, Kuoran Xing, Xiao Sun, Xiuli Jing.  (2025)  Nanoparticles induced glomerular endothelial leakiness promoting albuminuria level.  NanoImpact,    (100548). 
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