Determine the necessary mass, volume, or concentration for preparing a solution.
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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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F107712-20mg
|
20mg |
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
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$69.90
|
|
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F107712-100mg
|
100mg |
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
|
$229.90
|
|
|
F107712-500mg
|
500mg |
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
|
$699.90
|
|
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F107712-1g
|
1g |
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
|
$999.90
|
|
| Synonyms | 3,4',7-Tetrahydroxyflavone | 7,3',4'-Trihydroxyflavonol | HY-N0182 | MFCD00006829 | NCGC00095663-01 | 5-Deoxyquercetin | Fustet | UNII-OO2ABO9578 | BIDD:ER0141 | NSC407010 | NSC-407010 | Spectrum5_001797 | BRN 0292829 | C.I. Natural Brown 1 | KBioSS_00167 |
|---|---|
| Specifications & Purity | Moligand™, analytical standard, ≥98% |
| Storage Temp | Store at -20°C |
| Shipped In |
Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available. |
| Grade | analytical standard, Moligand™ |
Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Phenylpropanoids and polyketides |
| Class | Flavonoids |
| Subclass | Flavones |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Flavonols |
| Alternative Parents | 7-hydroxyflavonoids 4'-hydroxyflavonoids 3-hydroxyflavonoids 3'-hydroxyflavonoids Chromones Catechols Pyranones and derivatives 1-hydroxy-4-unsubstituted benzenoids 1-hydroxy-2-unsubstituted benzenoids Benzene and substituted derivatives Heteroaromatic compounds Oxacyclic compounds Organooxygen compounds Organic oxides Hydrocarbon derivatives |
| Molecular Framework | Aromatic heteropolycyclic compounds |
| Substituents | 3-hydroxyflavone - 3'-hydroxyflavonoid - 3-hydroxyflavonoid - 4'-hydroxyflavonoid - 7-hydroxyflavonoid - Hydroxyflavonoid - Chromone - Benzopyran - 1-benzopyran - Catechol - 1-hydroxy-4-unsubstituted benzenoid - 1-hydroxy-2-unsubstituted benzenoid - Phenol - Pyranone - Benzenoid - Monocyclic benzene moiety - Pyran - Heteroaromatic compound - Organoheterocyclic compound - Oxacycle - Hydrocarbon derivative - Organooxygen compound - Organic oxygen compound - Organic oxide - Aromatic heteropolycyclic compound |
| Description | This compound belongs to the class of organic compounds known as flavonols. These are compounds that contain a flavone (2-phenyl-1-benzopyran-4-one) backbone carrying a hydroxyl group at the 3-position. |
| External Descriptors | Flavones and Flavonols |
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| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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| IUPAC Name | 2-(3,4-dihydroxyphenyl)-3,7-dihydroxychromen-4-one |
|---|---|
| INCHI | InChI=1S/C15H10O6/c16-8-2-3-9-12(6-8)21-15(14(20)13(9)19)7-1-4-10(17)11(18)5-7/h1-6,16-18,20H |
| InChIKey | XHEFDIBZLJXQHF-UHFFFAOYSA-N |
| Smiles | C1=CC(=C(C=C1C2=C(C(=O)C3=C(O2)C=C(C=C3)O)O)O)O |
| Isomeric SMILES | C1=CC(=C(C=C1C2=C(C(=O)C3=C(O2)C=C(C=C3)O)O)O)O |
| RTECS | LK9250000 |
| Molecular Weight | 286.24 |
| Beilstein | 18221 |
| Reaxy-Rn | 292829 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=292829&ln= |
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | Jan 15, 2025 | F107712 | |
| Certificate of Analysis | Jan 15, 2025 | F107712 | |
| Certificate of Analysis | Jan 15, 2025 | F107712 | |
| Certificate of Analysis | Jan 15, 2025 | F107712 | |
| Certificate of Analysis | Mar 16, 2023 | F107712 | |
| Certificate of Analysis | Mar 16, 2023 | F107712 | |
| Certificate of Analysis | Mar 16, 2023 | F107712 | |
| Certificate of Analysis | Mar 16, 2023 | F107712 |
| Melt Point(°C) | 330°C |
|---|---|
| Molecular Weight | 286.240 g/mol |
| XLogP3 | 2.000 |
| Hydrogen Bond Donor Count | 4 |
| Hydrogen Bond Acceptor Count | 6 |
| Rotatable Bond Count | 1 |
| Exact Mass | 286.048 Da |
| Monoisotopic Mass | 286.048 Da |
| Topological Polar Surface Area | 107.000 Ų |
| Heavy Atom Count | 21 |
| Formal Charge | 0 |
| Complexity | 459.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
| 1. Nayun Kim, Junhye Kwon, Ui Sup Shin, Joohee Jung. (2023) Fisetin induces the upregulation of AKAP12 mRNA and anti-angiogenesis in a patient-derived organoid xenograft model. BIOMEDICINE & PHARMACOTHERAPY, 167 (115613). |
| 2. Fangjie Han, Shulin Luo, Zhifang Wu, Zhishan Liang, Wenxin Yang, Dongxue Han, Zhonghui Sun, Zhenbang Liu, Li Niu. (2023) A label-free photoelectrochemical sensor based on BiVO4@graphene oxide hybrid for analysis of the antioxidant capacity in food. JOURNAL OF ELECTROANALYTICAL CHEMISTRY, 946 (117713). |
| 3. Yufeng Chen, Guobin Xia, Chunfeng Wang, Huawei Wu, Xiaogang Xu, Genxiang Mao, Jiong Wu, Zhenlei Zhao. (2023) Impact of dietary plant flavonoids on 7,8-dihydroxyflavone transepithelial transport in human intestinal Caco-2 cells. Food Science & Nutrition, |
| 4. Xiao-Hua Zhang, Xiang-Dong Qing, Jing-Jing Zheng, Yan Yu, Jiaojiao Huang, Chao Kang, Zhi Liu. (2023) Aqueous two-phase systems coupled with chemometrics-enhanced HPLC-DAD for simultaneous extraction and determination of flavonoids in honey. Food Chemistry-X, 19 (100766). |
| 5. Sichao Gu, Xuefeng Zhou, Xingshi Yuan, Yunliang Zhu, Hui Zhang, Lei Xu, Li Li. (2023) Photocurable fisetin silk fibroin hydrogel accelerates infected diabetic wounds healing through biofilm inhibition and macrophage immunomodulation. MATERIALS LETTERS, 341 (134154). |
| 6. Ruiyi Fan, Congyi Zhu, Diyang Qiu, Genlin Mao, Bernd Mueller-Roeber, Jiwu Zeng. (2023) Integrated transcriptomic and metabolomic analyses reveal key genes controlling flavonoid biosynthesis in Citrus grandis ‘Tomentosa’ fruits. PLANT PHYSIOLOGY AND BIOCHEMISTRY, 196 (210). |
| 7. Chun Xiao Li, Fu Rong Wang, Bing Zhang, Ze Yuan Deng, Hong Yan Li. (2023) Stability and antioxidant activity of phenolic compounds during in vitro digestion. JOURNAL OF FOOD SCIENCE, 88 (2): (696-716). |
| 8. Hongting Deng, Yuanju He, Hui Cao, Lei Chen, Hui Teng. (2022) New insight into the effect of hydroxyl substituted flavonoids on the cytotoxicity of 2-amino-3-methylimidazo[4,5-f]quinoline. Food Frontiers, 4 (1): (289-296). |
| 9. Wenjie Yu, Fengjie Sun, Ruixin Xu, Meng Cui, Yongquan Liu, Quanyuan Xie, Limin Guo, Chenxian Kong, Xin Li, Xiali Guo, Liping Luo. (2023) Chemical composition and anti-inflammatory activities of Castanopsis honey. Food & Function, 14 (1): (250-261). |
| 10. Xiaochong Song, Qing Luo, Xiaojia Huang. (2022) Speciation of organotin compounds in water and seafood samples by online hyphenation of porous polymer-based magnetism-enhanced in-tube solid phase microextraction and HPLC. ANALYTICA CHIMICA ACTA, 1223 (340175). |
| 11. Ming Guan, Xiaojing Kang, Le Wei, Xingjun Hu, Chao Han, Xing Li, Hanwen Liu, Liang Qu, Zhenwen Zhao. (2022) A dual-mode strategy combining SERS with MALDI FTICR MS based on core-shell silver nanoparticles for dye identification and semi-quantification in unearthed silks from Tang Dynasty. TALANTA, 241 (123277). |
| 12. Zhang Xiao-Hua, Ma Yi-Xin, Yi Chong, Qing Xiang-Dong, Liu Zhi, Zheng Jing-Jing, Lin Fang, Lv Tian-Feng. (2020) Chemometrics-enhanced HPLC–DAD as a rapid and interference-free strategy for simultaneous quantitative analysis of flavonoids in Chinese propolis. EUROPEAN FOOD RESEARCH AND TECHNOLOGY, 246 (10): (1909-1918). |
| 13. Wei Yang, Zhi-Kai Tian, Hui-Xin Yang, Zhao-Jun Feng, Jian-Mei Sun, Hong Jiang, Chao Cheng, Qing-Lei Ming, Chan-Min Liu. (2019) Fisetin improves lead-induced neuroinflammation, apoptosis and synaptic dysfunction in mice associated with the AMPK/SIRT1 and autophagy pathway. FOOD AND CHEMICAL TOXICOLOGY, 134 (110824). |
| 14. Chengyun He, Xiaoling Liu, Zhaojing Jiang, Sheng Geng, Hanjun Ma, Benguo Liu. (2019) Interaction Mechanism of Flavonoids and α-Glucosidase: Experimental and Molecular Modelling Studies. Foods, 8 (9): (355). |
| 15. Ni Zeng, Guowen Zhang, Xing Hu, Junhui Pan, Deming Gong. (2019) Mechanism of fisetin suppressing superoxide anion and xanthine oxidase activity. Journal of Functional Foods, 58 (1). |
| 16. Yike Yue, Yongsheng Chen, Sheng Geng, Guizhao Liang, Benguo Liu. (2018) Antioxidant and α-Glucosidase Inhibitory Activities of Fisetin. Natural Product Communications, |
| 17. Hui Wang, Wenxi Zhang, Yatao Cheng, Xinyu Zhang, Nannan Xue, Gaorong Wu, Meng Chen, Kang Fang, Wenbo Guo, Fei Zhou, Herong Cui, Tao Ma, Penglong Wang, Haimin Lei. (2018) Design, Synthesis and Biological Evaluation of Ligustrazine-Flavonoid Derivatives as Potential Anti-Tumor Agents. MOLECULES, 23 (9): (2187). |
| 18. Tingting Wang, Huajuan Lin, Qian Tu, Jingjing Liu, Xican Li. (2016) Fisetin Protects DNA Against Oxidative Damage and Its Possible Mechanism. Advanced Pharmaceutical Bulletin, 6 (2): ( 267–270). |
| 19. Xiaodan Liu, Xia Wu. (2014) Fluorescence enhancement of fisetin by silver nanoparticles with cetyltrimethyl ammonium bromide micelles. RSC Advances, 5 (10): (7433-7439). |
| 20. Zhenning Xu, Mo Wang, Tingting Zhou, Huanshun Yin, Shiyun Ai. (2013) Electrochemical biosensing method for the detection of DNA methylation and assay of the methyltransferase activity. SENSORS AND ACTUATORS B-CHEMICAL, 178 (412). |
| 21. Huanshun Yin, Zhenning Xu, Mo Wang, Xueping Zhang, Shiyun Ai. (2013) An electrochemical biosensor for assay of DNA methyltransferase activity and screening of inhibitor. ELECTROCHIMICA ACTA, 89 (530). |
| 22. Huanshun Yin, Yunlei Zhou, Zhenning Xu, Lijian Chen, Di Zhang, Shiyun Ai. (2013) An electrochemical assay for DNA methylation, methyltransferase activity and inhibitor screening based on methyl binding domain protein. BIOSENSORS & BIOELECTRONICS, 41 (492). |
| 23. Shujuan Xu, Yong Shao, Kun Ma, Qinghua Cui, Guiying Liu, Fei Wu, Minjie Li. (2011) Fluorescence light-up recognition of DNA nucleotide based on selective abasic site binding of an excited-state intramolecular proton transfer probe. ANALYST, 136 (21): (4480-4485). |
| 24. Li-Feng Li, Meng-Di Wang, Chen-Yang Zhang, Meng-Yao Jin, Hua-Lei Chen, Huan Luo, Tian-Yu Hou, Zhi-Jun Zhang, He Li. (2025) Influence of hydroxyl substitution on the inhibition of flavonoids in advanced glycation end-products formation in glucose-lysine-arginine Maillard reaction models. FOOD RESEARCH INTERNATIONAL, 207 (116068). |