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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
|
F103702-20mg
|
20mg |
5
|
$31.90
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|
Hydroxycinnamic acid; antioxidant properties.
| Synonyms | (E)-3-(4-hydroxy-3-methoxy-phenyl)prop-2-enoic acid | (E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid | 3-(4-Hydroxy-3-methoxyphenyl)-2-propenoic acid | 3-(4-Hydroxy-3-methoxyphenyl)propenoic acid | bmse000587 | AVM951ZWST | DTXSID70892035 | ferulasaur |
|---|---|
| Specifications & Purity | analytical standard, ≥99.5%(HPLC) |
| Biochemical and Physiological Mechanisms | Hydroxycinnamic acid. Abundant phenolic phytochemical found in plant cell wall components. Antioxidant effects in vitro and in vivo. |
| Shipped In | Normal |
| Grade | analytical standard |
| Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Phenylpropanoids and polyketides |
| Class | Cinnamic acids and derivatives |
| Subclass | Hydroxycinnamic acids and derivatives |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Hydroxycinnamic acids |
| Alternative Parents | Coumaric acids and derivatives Cinnamic acids Methoxyphenols Styrenes Phenoxy compounds Methoxybenzenes Anisoles Alkyl aryl ethers 1-hydroxy-2-unsubstituted benzenoids Monocarboxylic acids and derivatives Carboxylic acids Organic oxides Hydrocarbon derivatives Carbonyl compounds |
| Molecular Framework | Aromatic homomonocyclic compounds |
| Substituents | Cinnamic acid - Coumaric acid or derivatives - Hydroxycinnamic acid - Methoxyphenol - Phenoxy compound - Anisole - Methoxybenzene - Styrene - Phenol ether - 1-hydroxy-2-unsubstituted benzenoid - Alkyl aryl ether - Phenol - Monocyclic benzene moiety - Benzenoid - Carboxylic acid derivative - Carboxylic acid - Monocarboxylic acid or derivatives - Ether - Organic oxygen compound - Carbonyl group - Organic oxide - Organooxygen compound - Hydrocarbon derivative - Aromatic homomonocyclic compound |
| Description | This compound belongs to the class of organic compounds known as hydroxycinnamic acids. These are compounds containing an cinnamic acid where the benzene ring is hydroxylated. |
| External Descriptors | Coniferyl alcohol derivatives |
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| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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| Pubchem Sid | 504758847 |
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| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/504758847 |
| IUPAC Name | (E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid |
| INCHI | InChI=1S/C10H10O4/c1-14-9-6-7(2-4-8(9)11)3-5-10(12)13/h2-6,11H,1H3,(H,12,13)/b5-3+ |
| InChIKey | KSEBMYQBYZTDHS-HWKANZROSA-N |
| Smiles | COC1=C(C=CC(=C1)C=CC(=O)O)O |
| Isomeric SMILES | COC1=C(C=CC(=C1)/C=C/C(=O)O)O |
| Molecular Weight | 194.18 |
| Reaxy-Rn | 1371483 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1371483&ln= |
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | Feb 28, 2025 | F103702 | |
| Certificate of Analysis | Oct 31, 2023 | F103702 | |
| Certificate of Analysis | Apr 10, 2023 | F103702 | |
| Certificate of Analysis | Mar 08, 2022 | F103702 |
| Solubility | Soluble in hot water, ethanol, and ethyl acetate. Easily soluble in ether, slightly soluble in benzene and petroleum ether. |
|---|---|
| Sensitivity | Moisture sensitive. |
| Melt Point(°C) | 169-173°C |
| Molecular Weight | 194.180 g/mol |
| XLogP3 | 1.500 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 4 |
| Rotatable Bond Count | 3 |
| Exact Mass | 194.058 Da |
| Monoisotopic Mass | 194.058 Da |
| Topological Polar Surface Area | 66.800 Ų |
| Heavy Atom Count | 14 |
| Formal Charge | 0 |
| Complexity | 224.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 1 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 1 |
| Covalently-Bonded Unit Count | 1 |
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| 2. Lijun Jing, Jun Lin, Qiqi Fei, Haowei Tang, Xiaodi Yang, Chong Sun. (2017) Simultaneous Quantitation of Caffeic Acid and Ferulic Acid Based on Graphite-like C3N4/chitosan Modified Film. International Journal of Electrochemical Science, 12 (8504). |
| 3. Jie Gao, Manqian Zhang, Xingwang Zu, Xue Gu, Erwei Hao, Xiaotao Hou, Gang Bai. (2023) Glucuronic acid metabolites of phenolic acids target AKT-PH domain to improve glucose metabolism. Chinese Herbal Medicines, |
| 4. Di Zhang, Bei Jing, Zhen-ni Chen, Xin Li, Hui-mei Shi, Ya-chun Zheng, Shi-quan Chang, Li Gao, Guo-ping Zhao. (2023) Ferulic acid alleviates sciatica by inhibiting neuroinflammation and promoting nerve repair via the TLR4/NF-κB pathway. CNS Neuroscience & Therapeutics, 29 (4): (1000-1011). |
| 5. Di Zhang, Bei Jing, Zhenni Chen, Xin Li, Huimei Shi, Yachun Zheng, Shiquan Chang, Guoping Zhao. (2022) Ferulic acid alleviates sciatica by inhibiting peripheral sensitization through the RhoA/p38MAPK signalling pathway. PHYTOMEDICINE, 106 (154420). |
| 6. Tao Long, Qian Wu, Jing Wei, Yong Tang, Yan-Ni He, Chang-Long He, Xue Chen, Lu Yu, Chong-Lin Yu, Betty Yuen-Kwan Law, Jian-Ming Wu, Da-Lian Qin, An-Guo Wu, Xiao-Gang Zhou. (2022) Ferulic Acid Exerts Neuroprotective Effects via Autophagy Induction in C. elegans and Cellular Models of Parkinson’s Disease. Oxidative Medicine and Cellular Longevity, 2022 (3723567). |
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| 33. Ligang Yu, Jing Wang, Yukun Yang, Caixia Guo, Meiping Li. (2024) Influence of selected phenolic acids on advanced lipid oxidation end products generation in model systems. Food Bioscience, 62 (105135). |
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