Grouped product items
SKU	Size	Availability	Price
Ab183319-100μg	100μg	10	$189.90
Ab183319-1mg	1mg	4	$919.90
Ab183319-5mg	5mg	1	$2,299.90
Ab183319-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$3,679.90

Purity>90% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Conjugated (MC-VC-PAB-MMAE)

View related series

Click to view target information: FOLR1

Accession#:P15328 (5) FBP (4) Folate Binding (1) FOLR1 (5) Gene ID:2348 (5) MC-VC-PAB-MMAE (18)

Basic Description

Product Name	Farletuzumab-MMAE (anti-FOLR1) - Primary antibody, specific to FOLR1, >90% (SDS-PAGE&SEC), high purity, Human IgG1
Synonyms	adult antibody \| Adult folate binding protein antibody \| Adult folate-binding protein antibody \| FBP antibody \| Folate Binding Protein antibody \| Folate Receptor 1 Adult antibody \| Folate receptor 1 antibody \| Folate Receptor 1 Precursor antibody \| Folate
Specifications & Purity	Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥90%(SDS-PAGE&SEC-HPLC), See COA
Host species	Human
Specificity	FOLR1
Conjugation	MC-VC-PAB-MMAE
Grade	Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Product Description	Farletuzumab-MMAE (anti-FOLR1) is an antibody-drug conjugate (ADC) composed of humanized anti-human folate receptor-alpha (FRα) and the cytotoxic agent monomethyl auristatin (MMAE) via a MC-Vc linker. It has a potent antitumor activity. Purity >90% (SDS-PAGE&SEC) Endotoxin Level < 1.0EU/mg

Product Properties

Isotype	Human IgG1
Light Chain Type	kappa
SDS-PAGE	145 kDa
Purification Method	Protein A purified
Purity	>90% (SDS-PAGE&SEC)
Shape	Liquid
Concentration	See COA
Storage Temp	Store at -80°C,Avoid repeated freezing and thawing
Shipped In	Ice chest + Ice pads
Stability And Storage	Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

Associated Targets(Human)

FOLR1 Tclin Folate receptor alpha (0 Activities)

Discover Target: FOLR1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Images

Flow Cytometry: Farletuzumab-MMAE (anti-FOLR1) (Ab183319)

Farletuzumab-MMAE (anti-FOLR1) (Ab183319) - Flow Cytometry
Flow Cytometry analysis of Hela cells labelling FOLR1 (red) with Farletuzumab-MMAE (anti-FOLR1) (Ab183319). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

Flow Cytometry: Farletuzumab-MMAE (anti-FOLR1) (Ab183319)

Farletuzumab-MMAE (anti-FOLR1) (Ab183319) - Flow Cytometry
Flow Cytometry analysis of MCF-7 cells labelling FOLR1 (red) with Farletuzumab-MMAE (anti-FOLR1) (Ab183319). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

SEC: Farletuzumab-MMAE (anti-FOLR1) (Ab183319)

Farletuzumab-MMAE (anti-FOLR1) (Ab183319) - SEC
The purity of Farletuzumab-MMAE (anti-FOLR1) (Ab183319) is more than 95% verified by HPLC.

ELISA: Farletuzumab-MMAE (anti-FOLR1) (Ab183319)

Farletuzumab-MMAE (anti-FOLR1) (Ab183319) - ELISA
Immobilized Recombinant Human FOLR1 protein (rp167844) at 1.0 μg/mL can bind Farletuzumab-MMAE (anti-FOLR1) (Ab183319) with the EC₅₀ of 36.63 ng/mL.

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot Number	Certificate Type	Date	Item
ZJ24F0607212	Certificate of Analysis	Jun 21, 2024	Ab183319
ZJ24F0607213	Certificate of Analysis	Jun 21, 2024	Ab183319
ZJ24F0607214	Certificate of Analysis	Jun 21, 2024	Ab183319

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Farletuzumab-MMAE (anti-FOLR1) - Primary antibody, specific to FOLR1, >90% (SDS-PAGE&SEC), high purity, Human IgG1