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Famotidine - 10mM in DMSO, high purity , CAS No.76824-35-6(DMSO), Histamine H2 receptor antagonist

1 Citations

COA

Grade & Purity:

Moligand™

10mM in DMSO

Cas Number: 76824-35-6(DMSO)
Molecular Weight: 337.45

In stock

Item Number

F408164

Grouped product items
SKU	Size	Availability	Price	Qty
F408164-1ml	1ml	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$173.90

H2 receptor Selective Agonists | Antagonists

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Compound libraries (12325)

Basic Description

Synonyms	MK208 \| 3-[[[2-[(aminoiminomethyl)amino]-4-thiazolyl]methyl]thio]-N-(aminosulfonyl)-propanimidamide
Specifications & Purity	Moligand™, 10mM in DMSO
Biochemical and Physiological Mechanisms	Famotidine (MK208) is a histamine H2–receptor antagonist with IC50 of 0.6 mM, commonly used to treat heartburn, GERD, ulcers, and other digestive conditions.
Storage Temp	Store at -80°C
Shipped In	Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available.
Grade	Moligand™
Action Type	AGONIST, ANTAGONIST
Mechanism of action	Histamine H2 receptor antagonist
Product Description	Information Famotidine (MK208) is a histamine H2–receptor antagonist with IC50 of 0.6 mM, commonly used to treat heartburn, GERD, ulcers, and other digestive conditions. In vitro In vivo Cell Data cell lines：HeLa, A43, SKOV-3, HT-29, K562, A549, Saos-2, MCF7, HCT116, COLO 205, Hep G2, Raji and PC-3 cells, etc. Concentrations： Incubation Time： Powder Purity:≥99%

Product Properties

ALogP	-1.328
hba_count	3
HBD Count	4
Rotatable Bond	9

Associated Targets(Human)

HRH2 Tclin Histamine H2 receptor (0 Activities)

Discover Target: HRH2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

TAS2R31 Tchem Taste receptor type 2 member 31 (0 Activities)

Discover Target: TAS2R31

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

Smiles	NC(=N)NC1=NC(=CS1)CSCCC(=N)N[S](N)(=O)=O
Molecular Weight	337.45
Reaxy-Rn	7226206
Reaxys-RN_link_address	https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=7226206&ln=

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Chemical and Physical Properties

Solubility	Solubility (25°C) In vitro DMSO: 55 mg/mL (198.35 mM); Water: Insoluble; Ethanol: Insoluble;
DMSO(mg / mL) Max Solubility	67
DMSO(mM) Max Solubility	198.55
Water(mg / mL) Max Solubility	<1

Citations of This Product

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