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Small Molecules & Compound Libraries
Signaling Pathways
Metabolic Enzyme/Protease
Mineralocorticoid Receptor
Esaxerenone - 98%, high purity , CAS No.1632006-28-0, Antagonist of Mineralocorticoid receptor

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Esaxerenone - 98%, high purity , CAS No.1632006-28-0, Antagonist of Mineralocorticoid receptor

COA

Grade & Purity:

Moligand™

≥98%

Cas Number: 1632006-28-0
Molecular Weight: 466.47
PubChem CID: 25052023

In stock

Item Number

E610186

Grouped product items
SKU	Size	Availability	Price
E610186-5mg	5mg	3	$139.90
E610186-25mg	25mg	3	$459.90
E610186-50mg	50mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$729.90
E610186-100mg	100mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,149.90

View related series

Glucose Metabolism (1943) Mineralocorticoid receptor Antagonist (14)

Basic Description

Synonyms	XL-550
Specifications & Purity	Moligand™, ≥98%
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available.
Grade	Moligand™
Action Type	ANTAGONIST
Mechanism of action	Antagonist of Mineralocorticoid receptor
Product Description	Esaxerenone (CS-3150) is a highly potent and selective non-steroidal mineralocorticoid receptor antagonist

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Benzenoids
  - Class Benzene and substituted derivatives
    - Subclass Anilides

Kingdom	Organic compounds
Superclass	Benzenoids
Class	Benzene and substituted derivatives
Subclass	Anilides
Intermediate Tree Nodes	Not available
Direct Parent	Aromatic anilides
Alternative Parents	Phenylpyrroles Trifluoromethylbenzenes Benzenesulfonyl compounds Pyrrole carboxamides Vinylogous amides Sulfones Heteroaromatic compounds Secondary carboxylic acid amides Azacyclic compounds Alkanolamines Primary alcohols Organofluorides Organic oxides Hydrocarbon derivatives Alkyl fluorides
Molecular Framework	Aromatic heteromonocyclic compounds
Substituents	Aromatic anilide - 2-phenylpyrrole - Trifluoromethylbenzene - Benzenesulfonyl group - Pyrrole-3-carboxamide - Pyrrole-3-carboxylic acid or derivatives - Substituted pyrrole - Pyrrole - Sulfone - Sulfonyl - Vinylogous amide - Heteroaromatic compound - Secondary carboxylic acid amide - Carboxamide group - Alkanolamine - Azacycle - Organoheterocyclic compound - Carboxylic acid derivative - Hydrocarbon derivative - Primary alcohol - Organic nitrogen compound - Organosulfur compound - Organooxygen compound - Organonitrogen compound - Organofluoride - Organohalogen compound - Organic oxygen compound - Organic oxide - Alkyl fluoride - Alkyl halide - Alcohol - Aromatic heteromonocyclic compound
Description	This compound belongs to the class of organic compounds known as aromatic anilides. These are aromatic compounds containing an anilide group in which the carboxamide group is substituted with an aromatic group. They have the general structure RNC(=O)R', where R= benzene, and R = aryl group.
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Associated Targets(Human)

NR3C2 Tclin Mineralocorticoid receptor (3 Activities)

Discover Target: NR3C2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

NR3C2 Tclin Mineralocorticoid receptor (2134 Activities)

Discover Target: NR3C2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

IUPAC Name	1-(2-hydroxyethyl)-4-methyl-N-(4-methylsulfonylphenyl)-5-[2-(trifluoromethyl)phenyl]pyrrole-3-carboxamide
INCHI	InChI=1S/C22H21F3N2O4S/c1-14-18(21(29)26-15-7-9-16(10-8-15)32(2,30)31)13-27(11-12-28)20(14)17-5-3-4-6-19(17)22(23,24)25/h3-10,13,28H,11-12H2,1-2H3,(H,26,29)
InChIKey	NOSNHVJANRODGR-UHFFFAOYSA-N
Smiles	CC1=C(N(C=C1C(=O)NC2=CC=C(C=C2)S(=O)(=O)C)CCO)C3=CC=CC=C3C(F)(F)F
Isomeric SMILES	CC1=C(N(C=C1C(=O)NC2=CC=C(C=C2)S(=O)(=O)C)CCO)C3=CC=CC=C3C(F)(F)F
PubChem CID	25052023
Molecular Weight	466.47

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

4 results found

Lot Number	Certificate Type	Date	Item
G2411127	Certificate of Analysis	Mar 18, 2024	E610186
G2411198	Certificate of Analysis	Mar 18, 2024	E610186
G2411196	Certificate of Analysis	Mar 18, 2024	E610186
G2411197	Certificate of Analysis	Mar 18, 2024	E610186

Chemical and Physical Properties

Molecular Weight	466.500 g/mol
XLogP3	2.900
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	7
Rotatable Bond Count	6
Exact Mass	466.117 Da
Monoisotopic Mass	466.117 Da
Topological Polar Surface Area	96.800 Å²
Heavy Atom Count	32
Formal Charge	0
Complexity	747.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

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