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Epiblastin A - ≥98%(HPLC), high purity , CAS No.16470-02-3

COA

Grade & Purity:

≥98%(HPLC)

Cas Number: 16470-02-3
Poids moléculaire: 287.71
PubChem CID: 118987042

En stock

Item Number

E286614

Articles du produit groupé
SKU	Taille	Disponibilité	Prix
E286614-5mg	5mg	3	58,90$US
E286614-10mg	10mg	2	78,90$US
E286614-25mg	25mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	137,90$US
E286614-50mg	50mg	2	197,90$US
E286614-100mg	100mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	335,90$US

CK1 inhibitor; converts epiblast stem cells to ESCs and promotes ESC self-renewal

View related series

Casein Kinase (72) Cell Cycle (2830) Cell Cycle/DNA Damage (2602) Stem Cell/Wnt (1019)

Description générale

Synonymes	6-(3-Chlorophenyl)-2,4,7-pteridinetriamine
Spécifications et pureté	≥98%(HPLC)
Mécanismes biochimiques et physiologiques	CK1 inhibitor (IC50values are 0.8, 3.7 and 3.8 μM for CK1δ, CK1ε and CK1α). Converts late-stage epiblast stem cells into germline-competent embryonic SC-like cells. Promotes activation and maintenance of the pluripotency network. Promotes ESC self-renewal
Température de stockage	Store at -20°C
Expédié en	Ice chest + Ice pads Ce produit nécessite l'expédition en chaîne froide. Les services terrestres et autres services économiques ne sont pas disponibles.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Organoheterocyclic compounds
  - Classe Pteridines and derivatives

Kingdom	Organic compounds
Superclass	Organoheterocyclic compounds
Classe	Pteridines and derivatives
Subclass	Not available
Intermediate Tree Nodes	Not available
Direct Parent	Pteridines and derivatives
Alternative Parents	Chlorobenzenes Aminopyrimidines and derivatives Aminopyrazines Imidolactams Aryl chlorides Heteroaromatic compounds Azacyclic compounds Primary amines Organopnictogen compounds Organochlorides Hydrocarbon derivatives
Molecular Framework	Aromatic heteropolycyclic compounds
Substituents	Pteridine - Halobenzene - Chlorobenzene - Aminopyrimidine - Aminopyrazine - Imidolactam - Benzenoid - Pyrimidine - Pyrazine - Monocyclic benzene moiety - Aryl halide - Aryl chloride - Heteroaromatic compound - Azacycle - Organic nitrogen compound - Organopnictogen compound - Hydrocarbon derivative - Primary amine - Organonitrogen compound - Organochloride - Organohalogen compound - Amine - Aromatic heteropolycyclic compound
Description	This compound belongs to the class of organic compounds known as pteridines and derivatives. These are polycyclic aromatic compounds containing a pteridine moiety, which consists of a pyrimidine fused to a pyrazine ring to form pyrimido(4,5-b)pyrazine.
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Noms et identifiants

IUPAC Name	6-(3-chlorophenyl)pteridine-2,4,7-triamine
INCHI	InChI=1S/C12H10ClN7/c13-6-3-1-2-5(4-6)7-9(14)18-11-8(17-7)10(15)19-12(16)20-11/h1-4H,(H6,14,15,16,18,19,20)
InChIKey	ZWNKKZSRANLVEW-UHFFFAOYSA-N
Smiles	C1=CC(=CC(=C1)Cl)C2=NC3=C(N=C(N=C3N=C2N)N)N
Poids moléculaire	287.71
Reaxy-Rn	291688
Reaxys-RN_link_address	https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=291688&ln=

Certificats (CoA, COO, BSE/TSE et tableau d'analyse)

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5 results found

Lot Number	Certificate Type	Date	Article
F2204373	Certificate of Analysis	Mar 04, 2025	E286614
F2204372	Certificate of Analysis	Mar 04, 2025	E286614
F2204370	Certificate of Analysis	Mar 04, 2025	E286614
F2204371	Certificate of Analysis	Mar 04, 2025	E286614
F2204369	Certificate of Analysis	Mar 04, 2025	E286614

Propriétés chimiques et physiques

Solubilité	Solvent:DMSO, Max Conc. mg/mL: 5.75, Max Conc. mM: 20
Poids moléculaire	287.710 g/mol
XLogP3	1.600
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	7
Rotatable Bond Count	1
Exact Mass	287.069 Da
Monoisotopic Mass	287.069 Da
Topological Polar Surface Area	130.000 Å²
Heavy Atom Count	20
Formal Charge	0
Complexity	344.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

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