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EGIS-7625 , CAS No.E610082, Antagonist of 5-HT 2A receptor;Antagonist of 5-HT 2B receptor;Antagonist of 5-HT 2C receptor

COA

Grade & Purity:

Moligand™

PubChem CID: 9930789

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Item Number

E610082

Grouped product items
SKU	Size	Availability	Price	Qty
E610082-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$600.90
E610082-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$2,000.90

View related series

5-HT2A receptor Antagonist (83) 5-HT2B receptor Antagonist (46) 5-HT2C receptor Antagonist (50)

Basic Description

Synonyms	EGIS-7625 free base \| UNII-ZD6AG3N96D \| ZD6AG3N96D \| 751462-86-9 \| Benzenamine, 2-methyl-4-nitro-5-(4-(phenylmethyl)-1-piperazinyl)- \| GTPL176 \| SCHEMBL7430234 \| DTXSID701177281 \| L017292 \| Q27077160 \| 2-methyl-4-nitro-5-[4-(phenylmethyl)piperazin-1-yl]aniline
Specifications & Purity	Moligand™
Grade	Moligand™
Action Type	ANTAGONIST
Mechanism of action	Antagonist of 5-HT 2A receptor;Antagonist of 5-HT 2B receptor;Antagonist of 5-HT 2C receptor

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Organoheterocyclic compounds
  - Class Diazinanes
    - Subclass Piperazines

Kingdom	Organic compounds
Superclass	Organoheterocyclic compounds
Class	Diazinanes
Subclass	Piperazines
Intermediate Tree Nodes	Not available
Direct Parent	Phenylpiperazines
Alternative Parents	N-arylpiperazines Nitrobenzenes Nitrotoluenes Aminotoluenes Aniline and substituted anilines Benzylamines Dialkylarylamines Nitroaromatic compounds Phenylmethylamines Aralkylamines N-alkylpiperazines Trialkylamines Propargyl-type 1,3-dipolar organic compounds Organic oxoazanium compounds Azacyclic compounds Hydrocarbon derivatives Primary amines Organic oxides Organic salts Organic zwitterions
Molecular Framework	Aromatic heteromonocyclic compounds
Substituents	Phenylpiperazine - N-arylpiperazine - Nitrobenzene - Nitrotoluene - Benzylamine - Phenylmethylamine - Nitroaromatic compound - Tertiary aliphatic/aromatic amine - Dialkylarylamine - Aniline or substituted anilines - Aminotoluene - Aralkylamine - Toluene - N-alkylpiperazine - Monocyclic benzene moiety - Benzenoid - Organic nitro compound - C-nitro compound - Tertiary amine - Tertiary aliphatic amine - Organic 1,3-dipolar compound - Azacycle - Organic oxoazanium - Propargyl-type 1,3-dipolar organic compound - Allyl-type 1,3-dipolar organic compound - Organic oxide - Hydrocarbon derivative - Amine - Primary amine - Organic salt - Organonitrogen compound - Organic nitrogen compound - Organic oxygen compound - Organic zwitterion - Aromatic heteromonocyclic compound
Description	This compound belongs to the class of organic compounds known as phenylpiperazines. These are compounds containing a phenylpiperazine skeleton, which consists of a piperazine bound to a phenyl group.
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Associated Targets(Human)

HTR2A Tclin 5-hydroxytryptamine receptor 2A (2 Activities)

Discover Target: HTR2A

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

HTR2C Tclin 5-hydroxytryptamine receptor 2C (1 Activities)

Discover Target: HTR2C

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

HTR2B Tclin 5-hydroxytryptamine receptor 2B (1 Activities)

Discover Target: HTR2B

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

IUPAC Name	2-methyl-4-nitro-5-[4-(phenylmethyl)piperazin-1-yl]aniline
INCHI	InChI=1S/C18H22N4O2/c1-14-11-18(22(23)24)17(12-16(14)19)21-9-7-20(8-10-21)13-15-5-3-2-4-6-15/h2-6,11-12H,7-10,13,19H2,1H3
InChIKey	ZEFXWOMFCPRXJW-UHFFFAOYSA-N
Smiles	Nc1cc(N2CCN(CC2)Cc2ccccc2)c(cc1C)[N+](=O)[O-]
Isomeric SMILES	CC1=CC(=C(C=C1N)N2CCN(CC2)CC3=CC=CC=C3)[N+](=O)[O-]
PubChem CID	9930789

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