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EA4 - 98%, high purity , CAS No.389614-94-2

    Grade & Purity:
  • ≥98%
In stock
Item Number
E649463
Grouped product items
SKU Size
Availability
Price Qty
E649463-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$90.90
E649463-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$155.90
E649463-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$340.90
E649463-50mg
50mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$580.90
E649463-100mg
100mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$980.90

Basic Description

Specifications & Purity ≥98%
Biochemical and Physiological Mechanisms EA4, a derivative of quinone, is an inhibitor for both rPLA and cPLA . EA4 can inhibit rPLA 2 with a K i value of 130 μM. EA4 can be used for the research of hemostasis, thrombosis, and erythropoiesis.
Storage Temp Store at 2-8°C,Protected from light,Desiccated
Shipped In
Wet ice
This product requires cold chain shipping. Ground and other economy services are not available.
Product Description

EA4, a derivative of quinone, is an inhibitor for both rPLA and cPLA . EA4 can inhibit rPLA 2 with a K i value of 130 μM. EA4 can be used for the research of hemostasis, thrombosis, and erythropoiesis

In Vitro

EA4 (9 μM, 24 μM) inhibits both rPLA 2 and cPLA 2. EA4 can inhibit rPLA 2 with a K i value of 130 μM. EA4 (50 μM) significantly inhibits A23187-induced AA release from both human and bovine RBCs in a time-dependent manner. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Form:Solid

IC50& Target:Ki: 130 μM (rPLA 2 )

Names and Identifiers

Smiles CCN(CC)C1=CC=C(C=C1)C2=C(C(=O)C3=C(C2=O)C=CC=N3)Cl
Isomeric SMILES CCN(CC)C1=CC=C(C=C1)C2=C(C(=O)C3=C(C2=O)C=CC=N3)Cl
PubChem CID 10042917
Molecular Weight 340.80

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Chemical and Physical Properties

Solubility DMSO : 50 mg/mL (146.71 mM; Need ultrasonic)
Molecular Weight 340.800 g/mol
XLogP3 4.000
Hydrogen Bond Donor Count 0
Hydrogen Bond Acceptor Count 4
Rotatable Bond Count 4
Exact Mass 340.098 Da
Monoisotopic Mass 340.098 Da
Topological Polar Surface Area 50.300 Ų
Heavy Atom Count 24
Formal Charge 0
Complexity 533.000
Isotope Atom Count 0
Defined Atom Stereocenter Count 0
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
The total count of all stereochemical bonds 0
Covalently-Bonded Unit Count 1

Solution Calculators

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