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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
|
E649463-5mg
|
5mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$90.90
|
|
|
E649463-10mg
|
10mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$155.90
|
|
|
E649463-25mg
|
25mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$340.90
|
|
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E649463-50mg
|
50mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$580.90
|
|
|
E649463-100mg
|
100mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$980.90
|
|
| Specifications & Purity | ≥98% |
|---|---|
| Biochemical and Physiological Mechanisms | EA4, a derivative of quinone, is an inhibitor for both rPLA and cPLA . EA4 can inhibit rPLA 2 with a K i value of 130 μM. EA4 can be used for the research of hemostasis, thrombosis, and erythropoiesis. |
| Storage Temp | Store at 2-8°C,Protected from light,Desiccated |
| Shipped In |
Wet ice This product requires cold chain shipping. Ground and other economy services are not available. |
| Product Description |
EA4, a derivative of quinone, is an inhibitor for both rPLA and cPLA . EA4 can inhibit rPLA 2 with a K i value of 130 μM. EA4 can be used for the research of hemostasis, thrombosis, and erythropoiesis In Vitro EA4 (9 μM, 24 μM) inhibits both rPLA 2 and cPLA 2. EA4 can inhibit rPLA 2 with a K i value of 130 μM. EA4 (50 μM) significantly inhibits A23187-induced AA release from both human and bovine RBCs in a time-dependent manner. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:Ki: 130 μM (rPLA 2 ) |
| Smiles | CCN(CC)C1=CC=C(C=C1)C2=C(C(=O)C3=C(C2=O)C=CC=N3)Cl |
|---|---|
| Isomeric SMILES | CCN(CC)C1=CC=C(C=C1)C2=C(C(=O)C3=C(C2=O)C=CC=N3)Cl |
| PubChem CID | 10042917 |
| Molecular Weight | 340.80 |
| Solubility | DMSO : 50 mg/mL (146.71 mM; Need ultrasonic) |
|---|---|
| Molecular Weight | 340.800 g/mol |
| XLogP3 | 4.000 |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 4 |
| Rotatable Bond Count | 4 |
| Exact Mass | 340.098 Da |
| Monoisotopic Mass | 340.098 Da |
| Topological Polar Surface Area | 50.300 Ų |
| Heavy Atom Count | 24 |
| Formal Charge | 0 |
| Complexity | 533.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |