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(E)-Cyclooct-4-enyl 2,5-dioxo-1-pyrrolidinyl carbonate - ≥83.0%, high purity , CAS No.1191901-33-3

COA

Grade & Purity:

≥83%

Cas Number: 1191901-33-3
Molecular Weight: 267.28
PubChem CID: 58490201
PubChem SID: 488201927

In stock

Item Number

E486554

Grouped product items
SKU	Size	Availability	Price
E486554-1mg	1mg	7	$22.90
E486554-5mg	5mg	6	$91.90
E486554-25mg	25mg	2	$382.90
E486554-100mg	100mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,375.90

View related series

Branched PEG (402) Hydroxy PEG (472) PEG NHS ester (198) PROTAC (2077) PROTAC Linkers (1898) TCO-PEG (107)

Basic Description

Synonyms	(E)-Cyclooct-4-enyl 2,5-dioxo-1-pyrrolidinyl carbonate \| SCHEMBL1300090 \| BP-22417 \| 1191901-33-3 \| TCO-NHS \| Carbonic acid, (4E)-4-cycloocten-1-yl 2,5-dioxo-1-pyrrolidinyl ester \| Tco-N-hydroxysuccinimidyl carbonate \| TCO-NHS ester \| 2249928-24-1 \| OUGQJ
Specifications & Purity	≥83%
Storage Temp	Store at -20°C,Argon charged
Shipped In	Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available.
Product Description	Description Succinimidyl carbonate/NHS functionalized cyclooctene derivative for incorporation of the cyclooctene moiety into amine containing compounds or biomolecules. Cyclooctenes are useful in strain-promoted copper-free click chemistry cycloaddition reactions with 1,2,4,5-tetrazines. This cyclooctene will react with tetrazine functionalized compounds or biomolecules without the need for a catalyst to result in a stable covalent linkage. The 4+2 inverse electron demand Diels-Alder cycloaddition between trans-cyclooctene and tetrazines is the fastest biologically compatible ligation technology reported and has had many applications in biological labeling and imaging.(E)-Cyclooct-4-enyl 2,5-dioxo-1-pyrrolidinyl carbonate may be used in the synthesis of vancomycin-TCO that can bind to the cell wall of gram-positive bacteria, which can subsequently react with tetrazine (Tz) decorated magneto-fluorescent nanoparticles orthogonally. This bioorthogonal labeling method is useful for the detection of gram-positive bacteria.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Organoheterocyclic compounds
  - Class Pyrrolidines
    - Subclass Pyrrolidones

Kingdom	Organic compounds
Superclass	Organoheterocyclic compounds
Class	Pyrrolidines
Subclass	Pyrrolidones
Intermediate Tree Nodes	Not available
Direct Parent	Pyrrolidine-2-ones
Alternative Parents	Dicarboximides Organic carbonic acids and derivatives Lactams Azacyclic compounds Organonitrogen compounds Organic oxides Hydrocarbon derivatives Carbonyl compounds
Molecular Framework	Aliphatic heteromonocyclic compounds
Substituents	2-pyrrolidone - Dicarboximide - Carbonic acid derivative - Lactam - Azacycle - Carboxylic acid derivative - Organic nitrogen compound - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Organonitrogen compound - Carbonyl group - Aliphatic heteromonocyclic compound
Description	This compound belongs to the class of organic compounds known as pyrrolidine-2-ones. These are pyrrolidines which bear a C=O group at position 2 of the pyrrolidine ring.
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Names and Identifiers

Pubchem Sid	488201927
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/488201927
IUPAC Name	[(4E)-cyclooct-4-en-1-yl] (2,5-dioxopyrrolidin-1-yl) carbonate
INCHI	InChI=1S/C13H17NO5/c15-11-8-9-12(16)14(11)19-13(17)18-10-6-4-2-1-3-5-7-10/h1-2,10H,3-9H2/b2-1+
InChIKey	OUGQJOKGFAIFAQ-OWOJBTEDSA-N
Smiles	C1CC=CCCC(C1)OC(=O)ON2C(=O)CCC2=O
Isomeric SMILES	C1C/C=C/CCC(C1)OC(=O)ON2C(=O)CCC2=O
Molecular Weight	267.28
Reaxy-Rn	27594158
Reaxys-RN_link_address	https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=27594158&ln=

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

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Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

6 results found

Lot Number	Certificate Type	Date	Item
F2302212	Certificate of Analysis	May 08, 2023	E486554
F2302214	Certificate of Analysis	May 08, 2023	E486554
F2302215	Certificate of Analysis	May 08, 2023	E486554
F2302216	Certificate of Analysis	May 08, 2023	E486554
F2302217	Certificate of Analysis	May 08, 2023	E486554
F2302213	Certificate of Analysis	May 08, 2023	E486554

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