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(E)-[6]-Dehydroparadol - ≥95.0%, high purity , CAS No.878006-06-5

COA

Grade & Purity:

≥95%

Cas Number: 878006-06-5
Molecular Weight: 276.37
PubChem CID: 6438480

In stock

Item Number

D649327

Grouped product items
SKU	Size	Availability	Price
D649327-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$108.90
D649327-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$180.90
D649327-50mg	50mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$456.90
D649327-100mg	100mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$576.90
D649327-500mg	500mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,176.90

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Basic Description

Specifications & Purity	≥95%
Biochemical and Physiological Mechanisms	(E)-[6]-Dehydroparadol, an oxidative metabolite of [6]-Shogaol ( HY-14616 ), is a potent Nrf2 activator. (E)-[6]-Dehydroparadol can inhibit the growth and induce the apoptosis of human cancer cells.
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available.
Product Description	(E)-[6]-Dehydroparadol, an oxidative metabolite of [6]-Shogaol , is a potent Nrf2 activator. (E)-[6]-Dehydroparadol can inhibit the growth and induce the apoptosis of human cancer cells In Vitro (E)-[6]-Dehydroparadol (M15) (5-80 µM; 24 h) inhibits the growth of HCT-116 and H-1299 cells, with IC 50 s of 43.02 and 41.59 µM, respectively. (E)-[6]-Dehydroparadol (10-40 µM; 24 h) induces apoptosis in HCT-116 and H-1299 cells. MCE has not independently confirmed the accuracy of these methods. They are for reference only. In Vivo (E)-[6]-Dehydroparadol (compound 19) (5 µM; 24 h) enhances Tg[glutathione S-transferase pi 1 (gstp1):green fluorescent protein (GFP)] fluorescence signal in the Tg(gstp1:GFP) transgenic zebrafish embryos. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:Nrf2

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

Smiles	CCCCCCCC(=O)/C=C/C1=CC(=C(C=C1)O)OC
Isomeric SMILES	CCCCCCCC(=O)/C=C/C1=CC(=C(C=C1)O)OC
PubChem CID	6438480
Molecular Weight	276.37

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Chemical and Physical Properties

Solubility	DMSO : ≥ 140 mg/mL (506.57 mM)
Molecular Weight	276.400 g/mol
XLogP3	4.700
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	9
Exact Mass	276.173 Da
Monoisotopic Mass	276.173 Da
Topological Polar Surface Area	46.500 Å²
Heavy Atom Count	20
Formal Charge	0
Complexity	299.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	1
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	1
Covalently-Bonded Unit Count	1

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