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Dyrk1A-IN-5 - 98%, high purity , CAS No.1685235-41-9

COA

Grade & Purity:

≥98%

Cas Number: 1685235-41-9
Molecular Weight: 388.16

In stock

Item Number

D648978

Grouped product items
SKU	Size	Availability	Price
D648978-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$320.90
D648978-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$510.90
D648978-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,050.90

View related series

DYRK (39) Non-receptor Tyrosine Kinase (643) Protein Tyrosine Kinase/RTK (1314)

Basic Description

Specifications & Purity	≥98%
Biochemical and Physiological Mechanisms	Dyrk1A-IN-5 (compound 5j) is a potent and selective DYRK1A inhibitor, with an IC 50 of 6 nM. Dyrk1A-IN-5 dose-dependently reduces the phosphorylation of Thr434 in SF3B1, with an IC 50 of 0.5 μM. Dyrk1A-IN-5 inhibits phosphorylation of tau at Thr212, with
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available.
Product Description	Dyrk1A-IN-5 (compound 5j) is a potent and selective DYRK1A inhibitor, with an IC 50 of 6 nM. Dyrk1A-IN-5 dose-dependently reduces the phosphorylation of Thr434 in SF3B1, with an IC 50 of 0.5 μM. Dyrk1A-IN-5 inhibits phosphorylation of tau at Thr212, with an IC 50 of 2.1 μM. Dyrk1A-IN-5 can be used for Down syndrome research Form:Solid IC50& Target:DYRK1A 6 nM (IC 50 ) DYRK1B 600 nM (IC 50 ) DYRK2 >10000 nM (IC 50 )

Names and Identifiers

Smiles	O=C(C1=NC2=CC=CC=C2C3=C1C4=C(N3)C(I)=CC=C4)O
Molecular Weight	388.16

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

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