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DS-7423 - 99%, high purity , CAS No.1222104-37-1

COA

Grade & Purity:

≥99%

Cas Number: 1222104-37-1
Molecular Weight: 520.51

In stock

Item Number

D651903

Grouped product items
SKU	Size	Availability	Price
D651903-1mg	1mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$214.90
D651903-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$450.90
D651903-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$800.90
D651903-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,650.90

View related series

mTOR (145) PI3K (243) PI3K/Akt/mTOR (765)

Basic Description

Specifications & Purity	≥99%
Biochemical and Physiological Mechanisms	DS-7423 is a dual PI3K and mTOR inhibitor, with IC 50 values of 15.6 nM, 34.9 nM for PI3Kα and mTOR , respectively. DS-7423 possesses anti-tumor activity.
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available.
Product Description	DS-7423 is a dual PI3K and mTOR inhibitor, with IC 50 values of 15.6 nM, 34.9 nM for PI3Kα and mTOR , respectively. DS-7423 possesses anti-tumor activity. In Vitro DS-7423 increases TP53 expression, the level of p-TP53 on Ser-46, and induced apoptosisrelated TP53 target genes (TP53AIP1 and PUMA) in OCCC cells. DS-7423 also inhibits other isoforms of class I PI3K (IC 50 values: PI3Kβ = 1,143 nM; PI3Kγ = 249 nM; PI3Kδ = 262 nM). MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid

Names and Identifiers

Smiles	CC(N1[C@H](C)CN(C2=NC3=C(N4CCOCC4)N=C(C5=CN=C(N)N=C5)N=C3N2CC(F)(F)F)CC1)=O
Molecular Weight	520.51

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