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| SKU | Size | Availability |
Price | Qty |
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D426737-1ml
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1ml |
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
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$182.90
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| Synonyms | AKOS016843634 | DTXCID30805 | HY-75161 | MENTHOL, UNSPECIFIED FORM | DTXSID8029650 | Menthol (USP) | DL-Menthol, analytical standard | Menthol racemate | 5-methyl-2-(propan-2-yl)cyclohexan-1-ol | Fisherman's friend lozenges | MFCD00062979 | BBL009325 | Cy |
|---|---|
| Specifications & Purity | Moligand™, 10mM in DMSO |
| Storage Temp | Store at -80°C |
| Shipped In |
Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available. |
| Grade | Moligand™ |
| Action Type | ACTIVATOR, GATING INHIBITOR |
| Mechanism of action | Activator of TRPA1;Gating inhibitor of TRPA1;Activator of TRPM8;Activator of TRPV3 |
| Product Description |
DL-Menthol triggers cold-sensitive TRPM8 receptors in the skin neurons in vitro. The (-)-Menthol form exists naturally in nature, primarily found in fruit extracts or spearmint extracts. This racemic mixture could theoretically be created by the hydrogenation of the monoterpene pulegone. |
Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Lipids and lipid-like molecules |
| Class | Prenol lipids |
| Subclass | Monoterpenoids |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Menthane monoterpenoids |
| Alternative Parents | Monocyclic monoterpenoids Cyclohexanols Cyclic alcohols and derivatives Hydrocarbon derivatives |
| Molecular Framework | Aliphatic homomonocyclic compounds |
| Substituents | P-menthane monoterpenoid - Monocyclic monoterpenoid - Cyclohexanol - Cyclic alcohol - Secondary alcohol - Organic oxygen compound - Hydrocarbon derivative - Organooxygen compound - Alcohol - Aliphatic homomonocyclic compound |
| Description | This compound belongs to the class of organic compounds known as menthane monoterpenoids. These are monoterpenoids with a structure based on the o-, m-, or p-menthane backbone. P-menthane consists of the cyclohexane ring with a methyl group and a (2-methyl)-propyl group at the 1 and 4 ring position, respectively. The o- and m- menthanes are much rarer, and presumably arise by alkyl migration of p-menthanes. |
| External Descriptors | a monoterpenol |
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| IUPAC Name | 5-methyl-2-propan-2-ylcyclohexan-1-ol |
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| INCHI | InChI=1S/C10H20O/c1-7(2)9-5-4-8(3)6-10(9)11/h7-11H,4-6H2,1-3H3 |
| InChIKey | NOOLISFMXDJSKH-UHFFFAOYSA-N |
| Smiles | CC(C)[C@@H]1CC[C@@H](C)C[C@H]1O |
| Isomeric SMILES | CC1CCC(C(C1)O)C(C)C |
| WGK Germany | 2 |
| RTECS | OT0350000 |
| Alternate CAS | 15356-70-4;1490-04-6 |
| Molecular Weight | 156.27 |
| Beilstein | 3194263 |
| Reaxy-Rn | 1902293 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1902293&ln= |
| Flash Point(°F) | 199.4 °F |
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| Flash Point(°C) | 93 °C |
| Boil Point(°C) | 216°C |
| Melt Point(°C) | 32-36°C |
| Molecular Weight | 156.260 g/mol |
| XLogP3 | 3.000 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 1 |
| Rotatable Bond Count | 1 |
| Exact Mass | 156.151 Da |
| Monoisotopic Mass | 156.151 Da |
| Topological Polar Surface Area | 20.200 Ų |
| Heavy Atom Count | 11 |
| Formal Charge | 0 |
| Complexity | 120.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 3 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
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| 3. Meichao Liao, Lin Yang, Xiaoyue Yang, Erxu Wang, Bin Lu, Jiye Wang, Li Duan. (2023) Vortex-assisted liquid–liquid microextraction based on hydrophobic deep eutectic solvent for the urinary excretion study of Taraxacum mongolicum extract in rats. MICROCHEMICAL JOURNAL, 184 (108167). |
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| 5. Heng Lu, Xiaohong Tan, Guobin Huang, Shaoru Wu, Yanmei Zhou, Junying Zhang, Qiaowen Zheng, Tianju Chen, Feiming Li, Zhixiong Cai, Jingbin Zeng, Maosheng Zhang. (2022) Green synthesis of highly stable CsPbBr3 perovskite nanocrystals using natural deep eutectic solvents as solvents and surface ligands. Nanoscale, 14 (46): (17222-17229). |
| 6. Jiaze Yan, Shaomin Ma, Mingrui Feng, Jiqi Zheng, Ming Guo. (2022) Hydrophobic deep eutectic solvent-based ultrasonic-assisted liquid-liquid microextraction combined with GC for eugenol, isoeugenol, and methyl isoeugenol determination in aquatic products. Food Additives and Contaminants Part A-Chemistry Analysis Control Exposure & Risk Assessment, |
| 7. Meichao Liao, Yang Zhao, Xiaoyue Yang, Lin Yang, E-Hu Liu, Bin Lu, Jiye Wang, Xiaopeng Liu, Yanzhong Chang, Li Duan. (2022) A greener and sustainable route for medicinal plant analysis: Recycle utilization of hydrophobic deep eutectic solvent. MICROCHEMICAL JOURNAL, 178 (107372). |
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| 9. Jing Li, Yanjun Jiao, Qin Luo, Weixin Hu, Shenwen Fang, Chunling Tang, Qiang Liu. (2021) Treatment of oil-based drill cuttings by hydrophobic deep eutectic solvents. CANADIAN JOURNAL OF CHEMICAL ENGINEERING, 100 (8): (1747-1754). |
| 10. Tong Wang, Qing Wang, Qing Guo, Ping Li, Hua Yang. (2021) A hydrophobic deep eutectic solvents-based integrated method for efficient and green extraction and recovery of natural products from Rosmarinus officinalis leaves, Ginkgo biloba leaves and Salvia miltiorrhiza roots. FOOD CHEMISTRY, 363 (130282). |
| 11. Ge Dandan, Wang Ying, Jiang Qian, Dai Enrui. (2019) A Deep Eutectic Solvent as an Extraction Solvent to Separate and Preconcentrate Parabens in Water Samples Using in situ Liquid-Liquid Microextraction. JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY, 30 (6): (1203-1210). |
| 12. Dandan Ge, Yi Zhang, Yixiu Dai, Shumin Yang. (2018) Air-assisted dispersive liquid–liquid microextraction based on a new hydrophobic deep eutectic solvent for the preconcentration of benzophenone-type UV filters from aqueous samples. JOURNAL OF SEPARATION SCIENCE, 41 (7): (1635-1643). |
| 13. Linzhou Zhuang, Beibei Ma, Siyu Chen, Xunan Hou, Shuixia Chen. (2015) Fast synthesis of mesoporous silica materials via simple organic compounds templated sol–gel route in the absence of hydrogen bond. MICROPOROUS AND MESOPOROUS MATERIALS, 213 (22). |
| 14. Jiaze Yan, Chao Jiang, Jiqi Zheng, Ming Guo. (2025) Enhanced microdialysis based on hydrophobic deep eutectic solvents for sampling of eugenol in Glyptocidaris crenularis. ANALYTICA CHIMICA ACTA, 1346 (343774). |