Basic Description

Synonyms	Amlodipine besilate impurity G \| Oprea1_609948 \| 3,5-PYRIDINEDICARBOXYLIC ACID, 4-(2-CHLOROPHENYL)-1,4-DIHYDRO-2,6-DIMETHYL-, 3,5-DIMETHYL ESTER \| FT-0667343 \| STK387362 \| EU-0035198 \| SCHEMBL3035724 \| SR-01000403200-1 \| REIGLQUFMMOAFU-UHFFFAOYSA-N \| SR-0
Specifications & Purity	≥95%
Storage Temp	Store at 2-8°C
Shipped In	Wet ice This product requires cold chain shipping. Ground and other economy services are not available.
Product Description	Dimethyl 4-(2-Chlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate (Amlodipine EP Impurity G) is an Amlodipine Besilate impurity.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Organoheterocyclic compounds
  - Class Pyridines and derivatives
    - Subclass Hydropyridines
      - Level5 Dihydropyridines
        Level6 Dihydropyridinecarboxylic acids and derivatives

Kingdom	Organic compounds
Superclass	Organoheterocyclic compounds
Class	Pyridines and derivatives
Subclass	Hydropyridines
Intermediate Tree Nodes	Dihydropyridines
Direct Parent	Dihydropyridinecarboxylic acids and derivatives
Alternative Parents	Chlorobenzenes Dicarboxylic acids and derivatives Aryl chlorides Vinylogous amides Methyl esters Enoate esters Amino acids and derivatives Enamines Dialkylamines Azacyclic compounds Organopnictogen compounds Organochlorides Organic oxides Hydrocarbon derivatives Carbonyl compounds
Molecular Framework	Aromatic heteromonocyclic compounds
Substituents	Dihydropyridinecarboxylic acid derivative - Chlorobenzene - Halobenzene - Aryl chloride - Aryl halide - Monocyclic benzene moiety - Benzenoid - Dicarboxylic acid or derivatives - Vinylogous amide - Alpha,beta-unsaturated carboxylic ester - Enoate ester - Methyl ester - Amino acid or derivatives - Carboxylic acid ester - Carboxylic acid derivative - Azacycle - Secondary aliphatic amine - Secondary amine - Enamine - Organic oxygen compound - Organic nitrogen compound - Hydrocarbon derivative - Amine - Carbonyl group - Organic oxide - Organooxygen compound - Organopnictogen compound - Organonitrogen compound - Organohalogen compound - Organochloride - Aromatic heteromonocyclic compound
Description	This compound belongs to the class of organic compounds known as dihydropyridinecarboxylic acids and derivatives. These are compounds containing a dihydropyridine moiety bearing a carboxylic acid group.
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Names and Identifiers

Pubchem Sid	504760070
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/504760070
IUPAC Name	dimethyl 4-(2-chlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
INCHI	InChI=1S/C17H18ClNO4/c1-9-13(16(20)22-3)15(11-7-5-6-8-12(11)18)14(10(2)19-9)17(21)23-4/h5-8,15,19H,1-4H3
InChIKey	REIGLQUFMMOAFU-UHFFFAOYSA-N
Smiles	CC1=C(C(C(=C(N1)C)C(=O)OC)C2=CC=CC=C2Cl)C(=O)OC
Isomeric SMILES	CC1=C(C(C(=C(N1)C)C(=O)OC)C2=CC=CC=C2Cl)C(=O)OC
Molecular Weight	335.78
Reaxy-Rn	3595219
Reaxys-RN_link_address	https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=3595219&ln=

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

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4 results found

Lot Number	Certificate Type	Date	Item
H2220031	Certificate of Analysis	Jun 10, 2025	D350035
H2220032	Certificate of Analysis	Jun 10, 2025	D350035
H2220084	Certificate of Analysis	Jun 10, 2025	D350035
H2220030	Certificate of Analysis	Jun 10, 2025	D350035

Chemical and Physical Properties

Solubility	Chloroform (Slightly), Dichloromethane (Slightly), DMSO (Slightly)
Melt Point(°C)	191-193°C
Molecular Weight	335.800 g/mol
XLogP3	3.000
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	5
Exact Mass	335.092 Da
Monoisotopic Mass	335.092 Da
Topological Polar Surface Area	64.599 Å²
Heavy Atom Count	23
Formal Charge	0
Complexity	529.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

Citations of This Product

How to Cite Aladdin Scientific Products?

1. Hongjian Huang, Yan Fang, Yunxiang Weng, Haiqing Liu. (2023) Photo-/electro-chromic underwater adhesive coacervate from self-assembly of zwitterions and polyoxometalate. Materials Today Chemistry, 32 (101670).
2. Zhi-Ang Liu, Ya-Nan Zuo, Yinghui Xia, Jing Sun, Shuyun Zhu. (2022) Enhanced detection of ascorbic acid with cascaded fluorescence recovery of a dual-nanoquencher system. Analytical Methods, 14 (37): (3632-3637).

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SKU	Size	Availability	Price
D350035-5mg	5mg	2	$83.90
D350035-25mg	25mg	2	$241.90
D350035-100mg	100mg	1	$687.90

Dimethyl 4-(2-Chlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate - 95%, high purity , CAS No.43067-01-2