JavaScript seems to be disabled in your browser. For the best experience on our site, be sure to turn on Javascript in your browser.

This is a demo store. No orders will be fulfilled.

Account

Settings

Language

྾

Home
Small Molecules & Compound Libraries
Signaling Pathways
GPCR/G Protein
Histamine Receptor
Dimaprit dihydrochloride - 10mM in DMSO, high purity , CAS No.23256-33-9

Skip to the end of the images gallery

Skip to the beginning of the images gallery

Dimaprit dihydrochloride - 10mM in DMSO, high purity , CAS No.23256-33-9

COA

Grade & Purity:

10mM in DMSO

Cas Number: 23256-33-9
Molecular Weight: 234.19
PubChem CID: 90045

In stock

Item Number

D422753

Grouped product items
SKU	Size	Availability	Price	Qty
D422753-1ml	1ml	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$69.90

Selective H 2 agonist

View related series

Class A GPCR (4138) Compound libraries (12325)

Basic Description

Synonyms	Dimaprit Dihydrochloride \| 23256-33-9 \| Dimaprit hydrochloride \| Dimaprit (hydrochloride) \| Dimaprit (dihydrochloride) \| 3-(dimethylamino)propyl carbamimidothioate dihydrochloride \| Diamaprit-2HCl \| 3-(dimethylamino)propyl carbamimidothioate;dihydrochloride \| USAF PD-40 \|
Specifications & Purity	10mM in DMSO
Biochemical and Physiological Mechanisms	Selective H 2 agonist. Some selectivity for H 3. Does not readily cross the blood-brain barrier. Systemically active following oral administration.
Storage Temp	Store at -80°C
Shipped In	Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available.
Product Description	Dimaprit dihydrochloride is a selective histamine H2 receptor agonist. Dimaprit dihydrochloride also inhibits nNOS with an IC50 of 49 μM. It can stimulate gastric acid secretion.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Organosulfur compounds
  - Class Isothioureas

Kingdom	Organic compounds
Superclass	Organosulfur compounds
Class	Isothioureas
Subclass	Not available
Intermediate Tree Nodes	Not available
Direct Parent	Isothioureas
Alternative Parents	Trialkylamines Sulfenyl compounds Carboximidamides Organopnictogen compounds Imines Hydrochlorides Hydrocarbon derivatives
Molecular Framework	Aliphatic acyclic compounds
Substituents	Tertiary aliphatic amine - Tertiary amine - Isothiourea - Sulfenyl compound - Carboximidamide - Organic nitrogen compound - Organopnictogen compound - Hydrocarbon derivative - Hydrochloride - Organonitrogen compound - Imine - Amine - Aliphatic acyclic compound
Description	This compound belongs to the class of organic compounds known as isothioureas. These are organic compounds containing the isothiourea group, with the general structure R1SC(=NR2)N(R3)R4 (R1,R2,R3,R4=H, alkyl, aryl).
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Associated Targets(Human)

HRH4 Tchem Histamine H4 receptor (0 Activities)

Discover Target: HRH4

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

IUPAC Name	3-(dimethylamino)propyl carbamimidothioate;dihydrochloride
INCHI	InChI=1S/C6H15N3S.2ClH/c1-9(2)4-3-5-10-6(7)8;;/h3-5H2,1-2H3,(H3,7,8);2*1H
InChIKey	DFWCPLGXFMSUCW-UHFFFAOYSA-N
Smiles	CN(C)CCCSC(=N)N.Cl.Cl
Isomeric SMILES	CN(C)CCCSC(=N)N.Cl.Cl
PubChem CID	90045
Molecular Weight	234.19

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Chemical and Physical Properties

Molecular Weight	234.190 g/mol
XLogP3
Hydrogen Bond Donor Count	4
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	5
Exact Mass	233.052 Da
Monoisotopic Mass	233.052 Da
Topological Polar Surface Area	78.400 Å²
Heavy Atom Count	12
Formal Charge	0
Complexity	103.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	3

Solution Calculators

Molarity Calculator

Determine the necessary mass, volume, or concentration for preparing a solution.

Mass

Concentration

Volume

M. Wt*

g/mol

*When preparing stock solutions, always use the batch-specific molecular weight of the product found on the vial label and the Certificate of Analysis (available online).

Dilution Calculator

Determine the dilution needed to prepare a stock solution.

Concentration 1 (C1)

Volume 1 (V1)

Concentration 2 (C2)

Volume 2 (V2)

Reconstitution Calculator

The reconstitution calculator enables you to quickly determine the volume of a reagent needed to reconstitute your vial. Just enter the mass of the reagent and the target concentration, and the calculator will do the rest.

Volume (to add to vial)

Mass (in vial)

Desired Reconstitution Concentration

Reviews

Shall we send you a message when we have discounts available?

Remind me later

Thank you! Please check your email inbox to confirm.

Oops! Notifications are disabled.