This is a demo store. No orders will be fulfilled.

Diisobutyl phthalate - 99%, high purity , CAS No.84-69-5

    Grade & Purity:
  • ≥99%
In stock
Item Number
D108909
Grouped product items
SKU Size
Availability
Price Qty
D108909-100ml
100ml
3
$9.90
D108909-500ml
500ml
2
$29.90

Basic Description

Synonyms DIBP | NCGC00259978-01 | di-2-methylpropyl phthalate | BIDD:ER0640 | Di(i-butyl)phthalate | DIISOBUTYL PHTHALATE | di-isobutyl phthalate | Di-iso-butyl phthalate | 1, bis(2-methylpropyl) ester | Hatcol DIBP | Q162259 | CHEBI:79053 | EC 201-553-2 | HMS2269
Specifications & Purity ≥99%
Shipped In Normal

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
Superclass Benzenoids
Class Benzene and substituted derivatives
Subclass Benzoic acids and derivatives
Intermediate Tree Nodes Not available
Direct Parent Benzoic acid esters
Alternative Parents Benzoyl derivatives  Dicarboxylic acids and derivatives  Carboxylic acid esters  Organooxygen compounds  Organic oxides  Hydrocarbon derivatives  
Molecular Framework Aromatic homomonocyclic compounds
Substituents Benzoate ester - Benzoyl - Dicarboxylic acid or derivatives - Carboxylic acid ester - Carboxylic acid derivative - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Aromatic homomonocyclic compound
Description This compound belongs to the class of organic compounds known as benzoic acid esters. These are ester derivatives of benzoic acid.
External Descriptors diester - phthalate ester

Associated Targets(Human)

AR Tclin Androgen Receptor (11781 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
TSHR Tclin Thyroid stimulating hormone receptor (29986 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
KCNH2 Tclin HERG (29587 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CXCL8 Tchem Interleukin-8 (642 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ALDH1A1 Tchem Aldehyde dehydrogenase 1A1 (77053 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
GLP1R Tclin Glucagon-like peptide 1 receptor (111429 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Lymphoblastoid cell (5959 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
GNAS Tbio Guanine nucleotide-binding protein G(s), subunit alpha (103405 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
KDM4A Tchem Lysine-specific demethylase 4A (52245 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CBX1 Tbio Chromobox protein homolog 1 (92434 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
BAZ2B Tchem Bromodomain adjacent to zinc finger domain protein 2B (56204 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Associated Targets(non-human)

Plasmodium falciparum (966862 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Nfe2l2 Nuclear factor erythroid 2-related factor 2 (214 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Names and Identifiers

IUPAC Name bis(2-methylpropyl) benzene-1,2-dicarboxylate
INCHI InChI=1S/C16H22O4/c1-11(2)9-19-15(17)13-7-5-6-8-14(13)16(18)20-10-12(3)4/h5-8,11-12H,9-10H2,1-4H3
InChIKey MGWAVDBGNNKXQV-UHFFFAOYSA-N
Smiles CC(C)COC(=O)C1=CC=CC=C1C(=O)OCC(C)C
Isomeric SMILES CC(C)COC(=O)C1=CC=CC=C1C(=O)OCC(C)C
WGK Germany 2
RTECS TI1225000
Molecular Weight 278.34
Beilstein 2054802
Reaxy-Rn 2054802
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2054802&ln=

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

7 results found

Lot Number Certificate Type Date Item
E1929088 Certificate of Analysis Mar 13, 2023 D108909
B2301577 Certificate of Analysis Feb 09, 2023 D108909
K2401070 Certificate of Analysis Oct 09, 2021 D108909
A2418085 Certificate of Analysis Oct 09, 2021 D108909
E2512085 Certificate of Analysis Oct 09, 2021 D108909
C2415142 Certificate of Analysis Oct 09, 2021 D108909
E2325049 Certificate of Analysis Oct 09, 2021 D108909

Chemical and Physical Properties

Solubility Insoluble in water; Degree of Solubility in water: 1 mg/l 20 °C; Soluble in Ethanol
Refractive Index 1.49
Flash Point(°C) 185℃
Boil Point(°C) 327°C
Melt Point(°C) -64°C
Molecular Weight 278.340 g/mol
XLogP3 4.100
Hydrogen Bond Donor Count 0
Hydrogen Bond Acceptor Count 4
Rotatable Bond Count 8
Exact Mass 278.152 Da
Monoisotopic Mass 278.152 Da
Topological Polar Surface Area 52.600 Ų
Heavy Atom Count 20
Formal Charge 0
Complexity 290.000
Isotope Atom Count 0
Defined Atom Stereocenter Count 0
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
The total count of all stereochemical bonds 0
Covalently-Bonded Unit Count 1

Citations of This Product

1. Xiumin Yang,Junmin Wang,Wenjin Wang,Shuaihua Zhang,Chun Wang,Junhong Zhou,Zhi Wang.  (2019-02-02)  Solid phase microextraction of polycyclic aromatic hydrocarbons by using an etched stainless-steel fiber coated with a covalent organic framework..  Mikrochimica acta,  186  ((3)): (145-145). 
2. Zhang Furong, Chen Hui, Liu Yuxuan, Wang Mingxin.  (2023)  Phthalate acid ester release from microplastics in water environment and their comparison between single and competitive adsorption.  ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH,  30  (56): (118964-118975). 
3. Wenhui Li, Xuecheng Zhang, Haojie Zhang, Cheng Zhang, Yingjie Chen, Cong Li, Yonghong Hu, Xiaoping Yu, Biao Zhang, Xiaodong Lin.  (2023)  A Nanozymatic-Mediated Smartphone Colorimetric Sensing Platform for the Detection of Dimethyl Phthalate (DMP) and Dibutyl Phthalate (DBP).  Biosensors-Basel,  13  (10): (919). 
4. Min Wang, Haibo Wang, Chisheng Hu, Jianmian Deng, Baoyou Shi.  (2023)  Phthalate acid esters promoted the enrichment of chlorine dioxide-resistant bacteria and their functions related to human diseases in rural polyvinyl chloride distribution pipes.  SCIENCE OF THE TOTAL ENVIRONMENT,  896  (165282). 
5. Zhefei Hu, Yanhao Jiang, Panpan Cao, Yanjuan Liu, Yuefei Zhang, Wei Chen, Sheng Tang.  (2023)  Performance evaluation of 2-undecylimidazole/propyl methacrylate bifunctional silica gel for mixed-mode reversed-phase/anion-exchange chromatography.  MICROCHEMICAL JOURNAL,  191  (108768). 
6. Yu-Xin Wang, Wang Zhang, Xiao-Fang Shen, Jin-Yu Qiao, Yue-Hong Pang.  (2023)  Magnetic covalent organic frameworks for rapid solid-phase extraction of phthalate esters and bisphenol A in beverage samples.  Analytical Methods,  15  (9): (1135-1144). 
7. Xiong Wang, Dong Wu, Xuemei Mu, Wenqian Kang, Guangquan Li, Anping Huang, Yuan Xie.  (2023)  Porous Organic Polymers-Supported Zeigler-Natta Catalysts for Preparing Highly Isotactic Polypropylene with Broad Molecular Weight Distribution.  Polymers,  15  (3): (555). 
8. Zhuo Wang, Xinyue Zhang, Qian Yang, Shuaihua Zhang, Guifen Chang, Xiaohuan Zang, Chun Wang, Zhi Wang.  (2022)  Covalent triazine-based frameworks for efficient solid-phase microextraction of phthalic acid esters from food-contacted plastics.  JOURNAL OF CHROMATOGRAPHY A,  1681  (463474). 
9. Xiong Wang, Wenqian Kang, Cuilan Zhang, Guangquan Li, Pingsheng Zhang, Yanqin Li.  (2022)  Sulfonated porous organic polymer supported Zeigler-Natta polypropylene catalysts with high stereoregularity and broad molecular weight distribution.  MICROPOROUS AND MESOPOROUS MATERIALS,  343  (112151). 
10. Ning Zhang, Dan Li, Mengyao Mu, Minghua Lu.  (2022)  Partially fluorinated UiO-66-NH2(Zr): Positive effect of the fluorine moiety on the adsorption capacity for environmental pollutants of metal–organic frameworks.  CHEMICAL ENGINEERING JOURNAL,  448  (137467). 
11. Jianqiang Sun, Haofeng Zhu, Xindong Yang, Yan Zheng, Tianchi Sun, Honglei Xu, Jiaqi Meng, Anping Zhang.  (2022)  Carboxylesterase and lipase-catalyzed degradation of phthalate esters in soil and water: Congener structure selectivity and specificity.  Environmental Technology & Innovation,  28  (102571). 
12. Fangyuan Hou, Qingyun Chang, Nana Wan, Jie Li, Xiaohuan Zang, Shuaihua Zhang, Chun Wang, Zhi Wang.  (2022)  A novel porphyrin-based conjugated microporous nanomaterial for solid-phase microextraction of phthalate esters residues in children's food.  FOOD CHEMISTRY,  388  (133015). 
13. Yan Wu, Kaixing Luo, Yanjuan Liu, Wei Chen, Zhengwu Bai, Sheng Tang.  (2022)  Innovative preparation of ureido/dodecyl dual-functionalized silica as a versatile mixed-mode stationary phase for high-resolution chromatographic separations.  JOURNAL OF CHROMATOGRAPHY A,  1665  (462834). 
14. Zhao Yuanli, Zhu Zhenbao, Liu Jianghua, Liu Jichao, Li Guoliang.  (2021)  Magnetic Solid-Phase Extraction Followed by HPLC–DAD for Highly Sensitive Determination of Phthalate Esters in Edible Vegetable Oils.  Food Analytical Methods,  14  (11): (2375-2385). 
15. Leng Yue, Sun Yonghai, Huang Wei, Lv Chengyu, Cui Jingyan, Li Tiezhu, Wang Yongjun.  (2021)  Identification of dicyclohexyl phthalate as a glucocorticoid receptor antagonist by molecular docking and multiple in vitro methods.  MOLECULAR BIOLOGY REPORTS,  48  (4): (3145-3154). 
16. Yinhui Yang, Meiling Qi, Jinliang Wang.  (2020)  Tetraphenylethylene-functionalized hexaphenylbenzene with unique conformation-driven selectivity for gas chromatographic separations.  NEW JOURNAL OF CHEMISTRY,  44  (7): (2890-2896). 
17. Yuan Hui, Hao Qian, Su Rongxin, Qi Wei, He Zhimin.  (2020)  Migration of phthalates from polyvinyl chloride film to fatty food simulants: experimental studies and model application.  Journal of Consumer Protection and Food Safety,  15  (2): (135-143). 
18. Zhong-Sheng Tang, Xin-An Zeng, Margaret A. Brennan, Zhong Han, Debao Niu, Yujia Huo.  (2019)  Characterization of aroma profile and characteristic aromas during lychee wine fermentation.  JOURNAL OF FOOD PROCESSING AND PRESERVATION,  43  (8): (e14003). 
19. Yanling Huang, Yue Lin, Fang Luo, Peilong Wang, Jian Wang, Bin Qiu, Longhua Guo, Zhenyu Lin.  (2019)  Rapid detection of dibutyl phthalate in liquor by a semi-quantitative multicolor immunosensor with naked eyes as readout.  Analytical Methods,  11  (4): (524-529). 
20. Cheng-bin Gong, Yu-bo Wei, Mei-jun Chen, Lan-tao Liu, Cheuk-fai Chow, Qian Tang.  (2018)  Double imprinted photoresponsive polymer for simultaneous detection of phthalate esters in plastics.  EUROPEAN POLYMER JOURNAL,  108  (295). 
21. Shuaihua Zhang, Qian Yang, Zhi Li, Wenjin Wang, Xiaohuan Zang, Chun Wang, Zhi Wang.  (2018)  Solid phase microextraction of phthalic acid esters from vegetable oils using iron (III)-based metal-organic framework/graphene oxide coating.  FOOD CHEMISTRY,  263  (258). 
22. Xinyu Liang, Juntao Wang, Qiuhua Wu, Chun Wang, Zhi Wang.  (2018)  Use of a hypercrosslinked triphenylamine polymer as an efficient adsorbent for the enrichment of phenylurea herbicides.  JOURNAL OF CHROMATOGRAPHY A,  1538  (1). 
23. Song Yuhong, Ma Ruiyang, Jiao Caina, Hao Lin, Wang Chun, Wu Qiuhua, Wang Zhi.  (2018)  Magnetic mesoporous polymelamine-formaldehyde resin as an adsorbent for endocrine disrupting chemicals.  MICROCHIMICA ACTA,  185  (1): (1-8). 
24. Wang Wenchang, Li Zhi, Wang Wenjin, Zhang Lihong, Zhang Shuaihua, Wang Chun, Wang Zhi.  (2018)  Microextraction of polycyclic aromatic hydrocarbons by using a stainless steel fiber coated with nanoparticles made from a porous aromatic framework.  MICROCHIMICA ACTA,  185  (1): (1-10). 
25. Jiajun DENG, Yanling ZHANG, Jiwei HU, Jiaguo JIAO, Feng HU, Huixin LI, Shixiang ZHANG.  (2017)  Autotoxicity of Phthalate Esters in Tobacco Root Exudates: Effects on Seed Germination and Seedling Growth.  PEDOSPHERE,  27  (1073). 
26. Jiao Caina, Ma Ruiyang, Li Menghua, Hao Lin, Wang Chun, Wu Qiuhua, Wang Zhi.  (2017)  Magnetic cobalt-nitrogen-doped carbon microspheres for the preconcentration of phthalate esters from beverage and milk samples.  MICROCHIMICA ACTA,  184  (8): (2551-2559). 
27. Yunzhong Zheng, Qing Han, Meiling Qi, Liangti Qu.  (2017)  Graphitic carbon nitride nanofibers in seaweed-like architecture for gas chromatographic separations.  JOURNAL OF CHROMATOGRAPHY A,  1496  (133). 
28. Zhang Jie, Li Tiezhu, Zhang Tiehua, Xue Peiyu, Guan Tianzhu, Yuan Yuan, Yu Hansong.  (2017)  Receptor-Based Fluorescence Polarization Assay to Detect Phthalate Esters in Chinese Spirits.  Food Analytical Methods,  10  (5): (1293-1300). 
29. Qian Zhou, Ailian Wang, Huayi Li, Zhi Luo, Tao Zheng, Liaoyun Zhang, Youliang Hu.  (2016)  Microstructure of polypropylene and active center in Ziegler–Natta catalyst: effect of novel salicylate internal donor.  RSC Advances,  (79): (75023-75031). 
30. Weiqian Liang, Juntao Wang, Xiaohuan Zang, Chun Wang, Zhi Wang.  (2016)  A porous carbon derived from amino-functionalized material of Institut Lavoisier as a solid-phase microextraction fiber coating for the extraction of phthalate esters from tea.  JOURNAL OF SEPARATION SCIENCE,  39  (7): (1331-1338). 
31. Jie Zhang, XiaoJia Xing, Yonghai Sun, Zhuolin Li, Peiyu Xue, Tuoyi Wang, Tiezhu Li.  (2016)  Characterization of the binding between phthalate esters and mouse PPARα for the development of a fluorescence polarization-based competitive binding assay.  Analytical Methods,  (4): (880-885). 
32. Xiping Cui, Panpan Wu, Dan Lai, Shengwu Zheng, Yingshan Chen, Sergei A. Eremin, Wei Peng, Suqing Zhao.  (2015)  Development of a Highly Specific Fluorescence Immunoassay for Detection of Diisobutyl Phthalate in Edible Oil Samples.  JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,  63  (42): (9372–9378). 
33. Xingli Liu, Chun Wang, Qiuhua Wu, Zhi Wang.  (2015)  Porous carbon derived from a metal–organic framework as an efficient adsorbent for the solid-phase extraction of phthalate esters.  JOURNAL OF SEPARATION SCIENCE,  38  (22): (3928-3935). 
34. Dang Xiaofei, Li Qian, Li Huayi, Yang Yuan, Zhang Liaoyun, Hu Youliang.  (2014)  Ziegler-Natta catalysts with novel internal electron donors for propylene polymerization.  JOURNAL OF POLYMER RESEARCH,  21  (12): (1-8). 
35. Qisi Lin, Ling Zhang, Dongzhi Yang, Zhao Chunjie.  (2014)  Contribution of Phenolics and Essential Oils to the Antioxidant and Antimicrobial Properties of Disporopsis pernyi (Hua) Diels.  JOURNAL OF MEDICINAL FOOD,  17  (6): (714-722). 
36. Xie Qilong, Liu Shuhui, Fan Yingying, Sun Jianzhi, Zhang Xiaoke.  (2014)  Determination of phthalate esters in edible oils by use of QuEChERS coupled with ionic-liquid-based dispersive liquid–liquid microextraction before high-performance liquid chromatography.  ANALYTICAL AND BIOANALYTICAL CHEMISTRY,  406  (18): (4563-4569). 
37. Jianzhi Sun, Hui He, Shuhui Liu.  (2014)  Determination of phthalic acid esters in Chinese white spirit using dispersive liquid–liquid microextraction coupled with sweeping β-cyclodextrin-modified micellar electrokinetic chromatography.  JOURNAL OF SEPARATION SCIENCE,  37  (13): (1679-1686). 
38. Meng Sun, Ranxiao Tang, Qiuhua Wu, Chun Wang, Zhi Wang.  (2013)  Graphene reinforced hollow fiber liquid-phase microextraction for the determination of phthalates in water, juice and milk samples by HPLC.  Analytical Methods,  (20): (5694-5700). 
39. Wang Wen-wen, Gao Fu-kai, Li Gui-zhi, Liu Zhen-bo, Liu Yong-ming.  (2013)  High efficient extraction of phthalates in aquatic products by a modified QuEChERS method.  CHEMICAL RESEARCH IN CHINESE UNIVERSITIES,  29  (4): (653-656). 
40. Yaxing Guo,Ruiyang Ma,Weihua Liu,Lin Hao,Qiuhua Wu,Zhi Wang.  (2020-05-10)  Facile synthesis of conjugated microporous polymer with spherical structure for solid phase extraction of phenyl urea herbicides..  Journal of chromatography. A,  1622  (461131-461131). 
41. Yali Yang, Jia Chen, Xiaojing Liang, Bei Liu, Kaijun Quan, Xiuhui Liu, Hongdeng Qiu.  (2024)  Adjustable chromatographic performance of silica-based mixed-mode stationary phase through the control of co-grafting amounts of imidazole and C18 chain.  JOURNAL OF CHROMATOGRAPHY A,  1722  (464889). 
42. Mengjie Qin, Mengmeng Zhou, Dongxue Li, Xuejing Lou, Jiawen Zhu, Xiao Tian, Ning Zhang, Wende Ma, Minghua Lu.  (2024)  Boronic acid functionalized of covalent organic framework for high performance capture of trace phthalates.  JOURNAL OF CHROMATOGRAPHY A,  1738  (465481). 
43. Haibo Wang, Min Wang, Yukang Li, Xinyuan Yang, Xueci Xing, Baoyou Shi.  (2025)  Chlorination enhances the phthalates release and increases the cytotoxicity and bacterial functions related to human disease of drinking water in plastic pipes.  WATER RESEARCH,  276  (123218). 
44. Mengge Duan, Yuting Wang, Shiyu Chen, Jiawen Lu, Ruihong Dong, Qiang Yu, Jianhua Xie, Yi Chen.  (2025)  Combined BPA and DIBP Exposure Induced Intestinal Mucosal Barrier Impairment Through the Notch Pathway and Gut Microbiota Dysbiosis in Mice.  Foods,  14  (2): (214). 
45. Guijiao Zhao, Chenhuan Wang, Min Kang, Lin Hao, Weihua Liu, Zhi Wang, Xiaodong Shi, Qiuhua Wu.  (2024)  Construction of magnetic azo-linked porous polymer for highly-efficient enrichment and separation of phenolic endocrine disruptors from environmental water and fish.  FOOD CHEMISTRY,  445  (138698). 
46. Yanbin Yu, Linlin Wang, Qing Yu, Qianru Wu, Yu He, Zongwei Cai.  (2025)  Investigation of interaction mechanism between polyvinyl chloride microplastics and phthalate acid esters using APGC-MS/MS.  TALANTA,  282  (126942). 
47. Li Han, Cui Yuanyuan, Zhen Changqing, Lin Xiaohui, Li Ke, Yang Chengxiong.  (2025)  Modification of Microporous Organic Network with Amino Acid for HILIC/RPLC Mixed-Mode High-Performance Liquid Chromatography.  Journal of Analysis and Testing,    (1-11). 
48. Ning Wang, Nan Zhang, Mei-Ling Sun, Yan Sun, Qing-Yu Dong, Yu Wang, Zeng-Tian Gu, Hai-Tao Ding, Qi-Long Qin, Yong Jiang, Xiu-Lan Chen, Yu-Zhong Zhang, Chao Gao, Chun-Yang Li.  (2024)  Molecular insights into the catalytic mechanism of a phthalate ester hydrolase.  JOURNAL OF HAZARDOUS MATERIALS,  476  (135191). 
49. Yaqiong Qin, Kunling Liu, Cong Nie, Fuwei Xie, Xiaoyu Wang, Ashraf Ali, Bing Wang, Qunye Hong, Wenjie Zhao.  (2025)  One pot preparation of magnetic benzylated cyclodextrin-based hyper-cross-linked polymer for phthalate esters extraction from tea beverages.  FOOD CHEMISTRY,  475  (143253). 
50. Wenqian Kang, Xiong Wang, Yue Ren, Pingsheng Zhang, Anping Huang, Guangquan Li.  (2024)  Sulfonated porous organic polymer supported Ziegler–Natta catalysts for the synthesis of ultra-high molecular weight polyethylene.  RSC Advances,  14  (47): (34578-34585). 

Solution Calculators

Reviews

Customer Reviews

Shall we send you a message when we have discounts available?

Remind me later

Thank you! Please check your email inbox to confirm.

Oops! Notifications are disabled.