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Dihydromyricetin - analytical standard，≥98%, high purity , CAS No.27200-12-0

23 Citations COA COA
In stock
Item Number
D101549
Grouped product items
SKU Size
Availability
 Price Qty
D101549-20mg
20mg
4
$103.90
D101549-100mg
100mg
5
$189.90
D101549-500mg
500mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$649.90
D101549-1g
1g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$999.90
D101549-5g
5g
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$3,433.90
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Basic Description

Synonyms (2R,3R)-2,3-dihydro-3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)-4H-1-benzopyran-4-one | HY-N0112 | Dihydromyricetin (Ampeloptin) | SW219328-1 | (+)-Dihydromyricetin | AKOS022168215 | AS-71702 | Dihydromyricetin | dihydro-myricetin | Dihydromyricetin, anal
Specifications & Purity analytical standard, ≥98%
Shipped In Normal
Grade analytical standard

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
Superclass Phenylpropanoids and polyketides
Class Flavonoids
Subclass Flavans
Intermediate Tree Nodes Flavan-3-ols - Catechins
Direct Parent Epigallocatechins
Alternative Parents 3'-hydroxyflavonoids  3-hydroxyflavonoids  4'-hydroxyflavonoids  5-hydroxyflavonoids  Flavanonols  7-hydroxyflavonoids  Chromones  Pyrogallols and derivatives  Aryl alkyl ketones  1-hydroxy-2-unsubstituted benzenoids  1-hydroxy-4-unsubstituted benzenoids  Alkyl aryl ethers  Benzene and substituted derivatives  Vinylogous acids  Secondary alcohols  Oxacyclic compounds  Polyols  Hydrocarbon derivatives  Organic oxides  
Molecular Framework Aromatic heteropolycyclic compounds
Substituents Epigallocatechin - 3'-hydroxyflavonoid - 3-hydroxyflavonoid - 4'-hydroxyflavonoid - 5-hydroxyflavonoid - 7-hydroxyflavonoid - Flavanone - Flavanonol - Hydroxyflavonoid - Chromone - Chromane - Benzopyran - 1-benzopyran - Benzenetriol - Pyrogallol derivative - Aryl alkyl ketone - Aryl ketone - Phenol - Alkyl aryl ether - 1-hydroxy-2-unsubstituted benzenoid - 1-hydroxy-4-unsubstituted benzenoid - Benzenoid - Monocyclic benzene moiety - Vinylogous acid - Ketone - Secondary alcohol - Polyol - Ether - Organoheterocyclic compound - Oxacycle - Alcohol - Hydrocarbon derivative - Organooxygen compound - Organic oxygen compound - Organic oxide - Aromatic heteropolycyclic compound
Description This compound belongs to the class of organic compounds known as epigallocatechins. These are compounds containing epigallocatechin or a derivative. Epigallocatechin is a flavan-3-ol containing a benzopyran-3,5,7-triol linked to a 3,4,5-hydroxyphenyl moiety.
External Descriptors Dihyroflavonols

Associated Targets(Human)

APP Tclin Amyloid-beta A4 protein (8510 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
SK-MEL-2 (46422 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
SK-OV-3 (52876 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
A549 (127892 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
BT-549 (31254 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
SYNJ2 Tchem Synaptojanin-2 (76 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Associated Targets(non-human)

Hdac6 Histone deacetylase 6 (222 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
C6 (2371 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
BV-2 (3710 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
SARS-CoV-2 (38078 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Names and Identifiers

IUPAC Name (2R,3R)-3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)-2,3-dihydrochromen-4-one
INCHI InChI=1S/C15H12O8/c16-6-3-7(17)11-10(4-6)23-15(14(22)13(11)21)5-1-8(18)12(20)9(19)2-5/h1-4,14-20,22H/t14-,15+/m0/s1
InChIKey KJXSIXMJHKAJOD-LSDHHAIUSA-N
Smiles C1=C(C=C(C(=C1O)O)O)C2C(C(=O)C3=C(C=C(C=C3O2)O)O)O
Isomeric SMILES C1=C(C=C(C(=C1O)O)O)[C@@H]2[C@H](C(=O)C3=C(C=C(C=C3O2)O)O)O
WGK Germany 3
Molecular Weight 320.25
Reaxy-Rn 332335
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=332335&ln=

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

9 results found

Lot Number Certificate Type Date Item
G2503022 Certificate of Analysis Jul 14, 2025 D101549
B2208351 Certificate of Analysis Nov 03, 2023 D101549
B2208262 Certificate of Analysis Nov 03, 2023 D101549
B2208258 Certificate of Analysis Nov 03, 2023 D101549
B2208259 Certificate of Analysis Nov 03, 2023 D101549
B2208264 Certificate of Analysis Nov 03, 2023 D101549
B2006101 Certificate of Analysis Sep 06, 2023 D101549
K1822067 Certificate of Analysis Jun 22, 2022 D101549
B2208260 Certificate of Analysis Aug 05, 2021 D101549

Chemical and Physical Properties

Specific Rotation[α] +15.5 to +17.0 deg(C=0.9, methanol)
Melt Point(°C) 248 °C
Molecular Weight 320.250 g/mol
XLogP3 1.100
Hydrogen Bond Donor Count 6
Hydrogen Bond Acceptor Count 8
Rotatable Bond Count 1
Exact Mass 320.053 Da
Monoisotopic Mass 320.053 Da
Topological Polar Surface Area 148.000 Ų
Heavy Atom Count 23
Formal Charge 0
Complexity 445.000
Isotope Atom Count 0
Defined Atom Stereocenter Count 2
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
The total count of all stereochemical bonds 0
Covalently-Bonded Unit Count 1

Citations of This Product

How to Cite Aladdin Scientific Products?
1. Chengyun He, Lu Bai, Daqun Liu, Benguo Liu.  (2023)  Interaction mechanism of okra (Abelmoschus esculentus L.) seed protein and flavonoids: Fluorescent and 3D-QSAR studies.  Food Chemistry-X,  20  (101023). 
2. Mingxiang Lu, Renzhi Liu, Zhifei Chen, Chen Su, Luqing Pan.  (2023)  Effects of dietary dihydromyricetin on growth performance, antioxidant capacity, immune response and intestinal microbiota of shrimp (Litopenaeus vannamei).  FISH & SHELLFISH IMMUNOLOGY,  142  (109086). 
3. Dongqing Zhang, Wenqi Liu, Ke Ye, Xiaojin Li.  (2024)  High CO and sulfur tolerant proton exchange membrane fuel cell anodes enabled by “work along both lines” mechanism of 2,6-dihydroxymethyl pyridine molecule blocking layer.  JOURNAL OF COLLOID AND INTERFACE SCIENCE,  653  (413). 
4. Shiyu Zhen, Sheng Geng, Hanjun Ma, Benguo Liu.  (2022)  Interaction of α-lactalbumin with dihydromyricetin and its application in nano-emulsion.  INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY,  58  (3): (1120-1129). 
5. Songqi Liu, Zaihan Chen, Huange Zhang, Yuanli Li, Taxipalati Maierhaba, Jianhui An, Zhi Zhou, Lingli Deng.  (2023)  Comparison of eugenol and dihydromyricetin loaded nanofibers by electro-blowing spinning for active packaging.  Food Bioscience,  51  (102294). 
6. Jie Zhao, Lin Huang, Renjie Li, Zhuangwei Zhang, Jin Chen, Hongjin Tang.  (2022)  Insights from multi-spectroscopic analysis and molecular modeling to understand the structure–affinity relationship and the interaction mechanism of flavonoids with gliadin.  Food & Function,  13  (9): (5061-5074). 
7. Xu Jinfang, Li Xinying, Xu Yaqin, Wang Anqi, Xu Zhilang, Wu Xia, Li Defu, Mu Changdao, Ge Liming.  (2021)  Dihydromyricetin-Loaded Pickering Emulsions Stabilized by Dialdehyde Cellulose Nanocrystals for Preparation of Antioxidant Gelatin–Based Edible Films.  Food and Bioprocess Technology,  14  (9): (1648-1661). 
8. Qian Zhou, Jia-Yi Yin, Wei-Yue Liang, Dong-Mei Chen, Qing Yuan, Bao-long Feng, Ying-Hua Zhang, Yu-Tang Wang.  (2021)  Various machine learning approaches coupled with molecule simulation in the screening of natural compounds with xanthine oxidase inhibitory activity.  Food & Function,  12  (4): (1580-1589). 
9. Hongjin Tang, Lin Huang, Dongsheng Zhao, Chunyong Sun, Ping Song.  (2020)  Interaction mechanism of flavonoids on bovine serum albumin: Insights from molecular property-binding affinity relationship.  SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,  239  (118519). 
10. Jie Zhao, Lin Huang, Chunyong Sun, Dongsheng Zhao, Hongjin Tang.  (2020)  Studies on the structure-activity relationship and interaction mechanism of flavonoids and xanthine oxidase through enzyme kinetics, spectroscopy methods and molecular simulations.  FOOD CHEMISTRY,  323  (126807). 
11. Chengyun He, Xiaoling Liu, Zhaojing Jiang, Sheng Geng, Hanjun Ma, Benguo Liu.  (2019)  Interaction Mechanism of Flavonoids and α-Glucosidase: Experimental and Molecular Modelling Studies.  Foods,  8  (9): (355). 
12. Hao Liu, Wenmei Zhao, Qi Hu, Ling Zhao, Yumeng Wei, Chao Pi, Yuhan Yang, Xuerong Yang, Hang Yuan, Yuhan Zhang, Kunyan Qu, Xinyu Shi, Yao Huang, Houyin Shi.  (2019)  Gastric floating sustained-release tablet for dihydromyricetin: Development, characterization, and pharmacokinetics study.  SAUDI PHARMACEUTICAL JOURNAL,  27  (1000). 
13. Meihui Fan, Huafang Ding, Guowen Zhang, Xing Hu, Deming Gong.  (2019)  Relationships of dietary flavonoid structure with its tyrosinase inhibitory activity and affinity.  LWT-FOOD SCIENCE AND TECHNOLOGY,  107  (25). 
14. Han Peng, Zeyuan Deng, Xuan Chen, Yong Sun, Bing Zhang, Hongyan Li.  (2018)  Major chemical constituents and antioxidant activities of different extracts from the peduncles of Hovenia acerba Lindl.  INTERNATIONAL JOURNAL OF FOOD PROPERTIES,     
15. Umair Muhammad, Hedong Lu, Juan Wang, Jinzhi Han, Xiaoyu Zhu, Zhaoxin Lu, Sultana Tayyaba, Yousef I. Hassan.  (2017)  Optimizing the Maximum Recovery of Dihydromyricetin from Chinese Vine Tea, Ampelopsis grossedentata, Using Response Surface Methodology.  MOLECULES,  22  (12): (2250). 
16. Han Peng, Wenting Li, Hongyan Li, Zeyuan Deng, Bing Zhang.  (2017)  Extractable and non-extractable bound phenolic compositions and their antioxidant properties in seed coat and cotyledon of black soybean (Glycinemax (L.) merr).  Journal of Functional Foods,  32  (296). 
17. Shuzhen Yang, Jie Zhou, Dongmei Li, Chunyu Shang, Litao Peng, Siyi Pan.  (2017)  The structure-antifungal activity relationship of 5,7-dihydroxyflavonoids against Penicillium italicum.  FOOD CHEMISTRY,  224  (26). 
18. Shimei Qi, Xianjuan Kou, Jun Lv, Zhilin Qi, Liang Yan.  (2015)  Ampelopsin induces apoptosis in HepG2 human hepatoma cell line through extrinsic and intrinsic pathways: Involvement of P38 and ERK.  ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY,  40  (847). 
19. Shian Zhong, Yanyue Kong, Ling Zhou, Chengyun Zhou, Xiaona Zhang, Yan Wang.  (2014)  Efficient conversion of myricetin from Ampelopsis grossedentata extracts and its purification by MIP-SPE.  JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES,  945-946  (39). 
20. Fei Wang, Xiang Yu, Haojie Li, Ming Li, Qimin Feng.  (2013)  Graphene-Nafion Composite Film Modified Electrode for Voltammetric Sensor for Determination of Dihydromyricetin.  JOURNAL OF THE CHINESE CHEMICAL SOCIETY,  60  (8): (1019-1026). 
21. Yimei Zheng, Boyu Chen, Xuanxiang Huang, Xiamei Tao, Chao Ai, Yanan Zhao, Peng Liang, Lei Chen.  (2024)  A designed self-microemulsifying delivery system: Stability and Anti-inflammation in vivo enhancement of dihydromyricetin.  Journal of Functional Foods,  118  (106266). 
22. Yucan Zhang, Chenxi Shi, Jin Yuan, Yue Zhang, Xiaohui Jin, Shaopo Zu, Honglei Zhang, Hui Hu.  (2024)  Rapid Construction of Recombinant PDCoV Expressing an Enhanced Green Fluorescent Protein for the Antiviral Screening Assay Based on Transformation-Associated Recombination Cloning in Yeast.  JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,  72  (2): (1124-1135). 
23. Mingxiang Lu, Futao Jing, Renzhi Liu, Zhifei Chen, Ruixue Tong, Yaobing Li, Luqing Pan.  (2024)  The effects and mechanisms of dietary ferulic acid (FA) and dihydromyricetin (DMY) on growth and physiological responses of the shrimp (Litopenaeus vannamei).  AQUACULTURE,  589  (740967). 

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