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| SKU | Size | Availability |
Price | Qty |
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D275915-10mg
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10mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$80.90
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D275915-25mg
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25mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$147.90
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Irreversible ornithine decarboxylase inhibitor
| Synonyms | (S)-eflornithine | 66640-93-5 (L-isomer) | C780YUS9YI | L-EFLORNITHINE | L-DFMO | HY-B0744C | (+)-alpha-difluoromethylornithine | (2S)-2,5-diamino-2-(difluoromethyl)pentanoic acid | AKOS030607731 | L-RMI71782 | BIDD:GT0723 | EFLORNITHINE, (S)- | (S)-2,5-d |
|---|---|
| Specifications & Purity | ≥98% |
| Biochemical and Physiological Mechanisms | Potent, irreversible ornithine decarboxylase inhibitor (K i = 39 μM). Depletes polyamines in vitro . Antineoplastic, cytotoxic and trypanocidal agent. Orally active. Active in vivo and in vitro . |
| Storage Temp | Store at -20°C,Desiccated |
| Shipped In |
Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available. |
| Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
| Product Description |
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. |
Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Organic acids and derivatives |
| Class | Carboxylic acids and derivatives |
| Subclass | Amino acids, peptides, and analogues |
| Intermediate Tree Nodes | Amino acids and derivatives - Alpha amino acids and derivatives - Alpha amino acids |
| Direct Parent | L-alpha-amino acids |
| Alternative Parents | D-alpha-amino acids Halogenated fatty acids Branched fatty acids Amino acids Monocarboxylic acids and derivatives Carboxylic acids Organopnictogen compounds Organofluorides Organic oxides Monoalkylamines Hydrocarbon derivatives Carbonyl compounds Alkyl fluorides |
| Molecular Framework | Aliphatic acyclic compounds |
| Substituents | D-alpha-amino acid - L-alpha-amino acid - Branched fatty acid - Halogenated fatty acid - Fatty acid - Fatty acyl - Amino acid - Carboxylic acid - Monocarboxylic acid or derivatives - Organopnictogen compound - Primary amine - Organooxygen compound - Organonitrogen compound - Organofluoride - Organohalogen compound - Alkyl fluoride - Primary aliphatic amine - Organic oxygen compound - Carbonyl group - Organic nitrogen compound - Amine - Alkyl halide - Organic oxide - Hydrocarbon derivative - Aliphatic acyclic compound |
| Description | This compound belongs to the class of organic compounds known as l-alpha-amino acids. These are alpha amino acids which have the L-configuration of the alpha-carbon atom. |
| External Descriptors | Not available |
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| IUPAC Name | (2S)-2,5-diamino-2-(difluoromethyl)pentanoic acid |
|---|---|
| INCHI | InChI=1S/C6H12F2N2O2/c7-4(8)6(10,5(11)12)2-1-3-9/h4H,1-3,9-10H2,(H,11,12)/t6-/m1/s1 |
| InChIKey | VLCYCQAOQCDTCN-ZCFIWIBFSA-N |
| Smiles | C(CC(C(F)F)(C(=O)O)N)CN |
| Isomeric SMILES | C(C[C@@](C(F)F)(C(=O)O)N)CN |
| Reaxy-Rn | 2250529 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2250529&ln= |
| Solubility | Soluble in water |
|---|---|
| Molecular Weight | 182.170 g/mol |
| XLogP3 | -2.900 |
| Hydrogen Bond Donor Count | 3 |
| Hydrogen Bond Acceptor Count | 6 |
| Rotatable Bond Count | 5 |
| Exact Mass | 182.087 Da |
| Monoisotopic Mass | 182.087 Da |
| Topological Polar Surface Area | 89.300 Ų |
| Heavy Atom Count | 12 |
| Formal Charge | 0 |
| Complexity | 166.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 1 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |