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Dicyclohexylmethane 4,4'-Diisocyanate (mixture of isomers) - >90.0%(GC), high purity , CAS No.5124-30-1

    Grade & Purity:
  • ≥90%(GC)
In stock
Item Number
D155475
Grouped product items
SKU Size
Availability
Price Qty
D155475-5g
5g
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$9.90
D155475-25g
25g
3
$18.90
D155475-100g
100g
3
$25.90
D155475-500g
500g
3
$74.90

Basic Description

Synonyms HMDI | AKOS000120188 | Cyclohexane, 1,1'-methylenebis[4-isocyanato-, (trans,trans)- | D2380 | SCHEMBL8733246 | TRANS-TRANS-METHYLENEBIS(4-CYCLOHEXYLISOCYANATE) | Isocyanic acid, methylenedi-4,1-cyclohexylene ester, cis,cis- | 4,4'-Diisocyanatodicyclohexyl
Specifications & Purity ≥90%(GC)
Storage Temp Store at 2-8°C,Argon charged
Shipped In
Wet ice
This product requires cold chain shipping. Ground and other economy services are not available.
Product Description

4,4′-Methylenebis(cyclohexyl isocyanate), mixture of isomers (HMDI) is an aromatic diisocyanate with good mechanical properties. It is light stable and is resistant to hydrolysis. It is majorly used in the synthesis of polyurethane.
Application
HMDI forms NCO linkages which can be used in the synthesis of polyurethanes for a variety of biomedical applications.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
Superclass Organic nitrogen compounds
Class Organonitrogen compounds
Subclass Isocyanates
Intermediate Tree Nodes Not available
Direct Parent Isocyanates
Alternative Parents Propargyl-type 1,3-dipolar organic compounds  Organopnictogen compounds  Organooxygen compounds  Organic oxides  Hydrocarbon derivatives  
Molecular Framework Aliphatic homomonocyclic compounds
Substituents Isocyanate - Organic 1,3-dipolar compound - Propargyl-type 1,3-dipolar organic compound - Organic oxygen compound - Organopnictogen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Aliphatic homomonocyclic compound
Description This compound belongs to the class of organic compounds known as isocyanates. These are organic compounds containing the isocyanic acid tautomer, HN=C=O, of cyanic acid, HOC#N or its hydrocarbyl derivatives RN=C=O.
External Descriptors diisocyanate

Associated Targets(Human)

AR Tclin Androgen Receptor (11781 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Names and Identifiers

IUPAC Name 1-isocyanato-4-[(4-isocyanatocyclohexyl)methyl]cyclohexane
INCHI InChI=1S/C15H22N2O2/c18-10-16-14-5-1-12(2-6-14)9-13-3-7-15(8-4-13)17-11-19/h12-15H,1-9H2
InChIKey KORSJDCBLAPZEQ-UHFFFAOYSA-N
Smiles C1CC(CCC1CC2CCC(CC2)N=C=O)N=C=O
Isomeric SMILES C1CC(CCC1CC2CCC(CC2)N=C=O)N=C=O
RTECS NQ9250000
UN Number 2206
Packing Group II
Molecular Weight 262.35
Reaxy-Rn 2217800
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2217800&ln=

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

15 results found

Lot Number Certificate Type Date Item
L2011089 Certificate of Analysis Sep 09, 2024 D155475
G2425764 Certificate of Analysis Apr 12, 2024 D155475
G2425765 Certificate of Analysis Apr 12, 2024 D155475
I2413339 Certificate of Analysis Apr 12, 2024 D155475
I2413340 Certificate of Analysis Apr 12, 2024 D155475
B2510024 Certificate of Analysis Jan 10, 2024 D155475
A2422271 Certificate of Analysis Jan 10, 2024 D155475
A2422270 Certificate of Analysis Jan 10, 2024 D155475
A2314117 Certificate of Analysis Dec 28, 2022 D155475
A2314116 Certificate of Analysis Dec 28, 2022 D155475
F2420056 Certificate of Analysis Dec 28, 2022 D155475
L2411279 Certificate of Analysis Dec 28, 2022 D155475
A2314126 Certificate of Analysis Dec 28, 2022 D155475
A2314100 Certificate of Analysis Dec 28, 2022 D155475
J2227156 Certificate of Analysis Oct 31, 2022 D155475

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Chemical and Physical Properties

Solubility Soluble in water; Soluble in Acetone
Sensitivity Moisture sensitive;Heat sensitive
Refractive Index 1.5
Boil Point(°C) 168 °C/1.5 mmHg
Molecular Weight 262.350 g/mol
XLogP3 5.300
Hydrogen Bond Donor Count 0
Hydrogen Bond Acceptor Count 4
Rotatable Bond Count 4
Exact Mass 262.168 Da
Monoisotopic Mass 262.168 Da
Topological Polar Surface Area 58.900 Ų
Heavy Atom Count 19
Formal Charge 0
Complexity 332.000
Isotope Atom Count 0
Defined Atom Stereocenter Count 0
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
The total count of all stereochemical bonds 0
Covalently-Bonded Unit Count 1

Alternative Products

Citations of This Product

1. Hao Jiang, Wuting Pang, Meng Cheng, Tong Yan, Zhikun Wang, Zhihao Zhao, Chunling Li, Shuangqing Sun, Songqing Hu.  (2024)  Construction and mechanism of phase-locked structured PU elastomers with tunable mechanical and self-healing properties.  APPLIED SURFACE SCIENCE,  649  (159136). 
2. Di Zhao, Chunmei Yue, Qianrui Li, Lei Guo, Jing Yang, Huanrong Li.  (2023)  Self-Healing Luminescent Elastomers with Ultrahigh Mechanical Strength, Superior Toughness, and Stimuli-Responsive Luminescence.  ACS Applied Polymer Materials,  (11): (9375–9384). 
3. Changyuan Song, Yin Jin.  (2023)  Distribution-according-to-work: Enhancing solar vapor generation of photothermal sponge by using cellulose-based water storage platform.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,  253  (126830). 
4. Jingcheng Liu, Jun Hu, Jian Li, Yue Zhang, Xiaojie Li.  (2023)  Preparation of UV-curable strippable coatings based on polyurethane acrylate from CO2-polyol and different isocyanates.  PROGRESS IN ORGANIC COATINGS,  184  (107865). 
5. Yujia Hao, Guangming Zhu, Ben Li.  (2023)  Mechanically Robust and Self-Healable Polyureas Based on Multiple Dynamic Bonds.  INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH,  62  (27): (10444–10453). 
6. Zheng Yuan, Jun Yan, Feng Gao, Jue Cheng, Junying Zhang.  (2023)  High-performance, fluorescent, UV-shielding, triboelectric, super-flexible polyurea elastomers via strong π–π stacking of pyrene and hydrogen bonding strategies.  Journal of Materials Chemistry C,  11  (26): (8971-8981). 
7. Xin-Yi Zhang, Kai-Li Tian, Jie Liu, Wittaya Ngeontae, Ai-Juan Zhao, Maxim V. Bermeshev, Shi-Qing Wong, Kaspars Traskovskis, Zhijian Chen, Xiang-Kui Ren.  (2023)  Perylene Diimide Incorporated Polyurethane Polymer as Potential Colour Filter Material with Non-fluorescent Property†.  CHINESE JOURNAL OF CHEMISTRY,  41  (11): (1348-1354). 
8. Lulu Xiong, Delong Li, Yongfei Yang, Xiaoxiao Ye, Yu Huang, E. Xu, Chuanhui Xia, Mingbo Yang, Zhengying Liu, Xudong Cui, Feng Wang, Yanhao Huang.  (2023)  Tailoring crosslinking networks to fabricate photocurable polyurethane acrylate (PUA) dielectric elastomer with balanced electromechanical performance.  REACTIVE & FUNCTIONAL POLYMERS,  183  (105498). 
9. Gang Tang, Dongli Wang, Chunyan Chen, Yunjun Luo, Xiaoyu Li.  (2023)  High Performance Thermoplastic Energetic Composites Using Fluorinated Energetic Polyurethanes as Binder.  PROPELLANTS EXPLOSIVES PYROTECHNICS,  48  (3): (e202200249). 
10. S.J. Ding, G.C. Zhu, S. Zhao, L. Zhou, Y.J. Luo.  (2023)  Enhanced self-healing driving force in polymer materials by regulating molecular structure.  Materials Today Chemistry,  27  (101278). 
11. Changyuan Song, Yin Jin, Xiangyi Gu, Jianwei Shi.  (2023)  A solar-driven self-repairing sponge for efficient recovery of crude oil.  COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS,  658  (130692). 
12. Xiaobo Zhu, Wujun Zhang, Guangming Lu, Haichao Zhao, Liping Wang.  (2022)  Ultrahigh Mechanical Strength and Robust Room-Temperature Self-Healing Properties of a Polyurethane–Graphene Oxide Network Resulting from Multiple Dynamic Bonds.  ACS Nano,  16  (10): (16724–16735). 
13. Changyuan Song, Muhammad Sultan Irshad, Yin Jin, Junhua Hu, Wentao Liu.  (2022)  Arabic-dome-inspired hierarchical design for stable and high-efficiency solar-driven seawater desalination.  DESALINATION,  544  (116125). 
14. Yinglu Sun, Xinxin Tian, Haopu Xie, Biru Shi, Jiahui Zhong, Xiangdong Liu, Yuming Yang.  (2022)  Reprocessable and degradable bio-based polyurethane by molecular design engineering with extraordinary mechanical properties for recycling carbon fiber.  POLYMER,  258  (125313). 
15. Gang Tang, He Wang, Chunyan Chen, Yabei Xu, Dongping Chen, Dongli Wang, Yunjun Luo, Xiaoyu Li.  (2022)  Thermal decomposition of nano Al-based energetic composites with fluorinated energetic polyurethane binders: experimental and theoretical understandings for enhanced combustion and energetic performance.  RSC Advances,  12  (37): (24163-24171). 
16. Qingyuan Zeng, Shujing Xue, Jianping Li, Wenhui Jiang, Yongbo Ding, Liang Shen.  (2022)  Preparation of bio-based air-drying water-borne polyurea coatings with excellent coating properties and anticorrosive performance.  PROGRESS IN ORGANIC COATINGS,  171  (107040). 
17. Gang Tang, Dongli Wang, Yunjun Luo, Xiaoyu Li.  (2022)  Novel azide-rich fluorinated energetic polyurethane with excellent mechanical properties by a one-pot facile strategy.  EUROPEAN POLYMER JOURNAL,  177  (111428). 
18. Xueqi Wu, Maochen Liu, Jiang Zhong, Yuting Zhong, Jinchuang Rong, Fei Gao, Yongluo Qiao, Liang Shen, Haifeng He.  (2022)  Self-healing dynamic bond-based robust polyurethane acrylate hybrid polymers.  NEW JOURNAL OF CHEMISTRY,  46  (28): (13415-13421). 
19. Li Yan Mei, Zhang Ze Ping, Rong Min Zhi, Zhang Ming Qiu.  (2022)  Tailored modular assembly derived self-healing polythioureas with largely tunable properties covering plastics, elastomers and fibers.  Nature Communications,  13  (1): (1-10). 
20. Jing Yan, Xuezhuang Li, Xue Zhang, Shuang Liu, Fenglin Zhong, Junping Zhang, Qiuyu Zhang, Yi Yan.  (2022)  Metallo-Polyelectrolyte-Based Waterborne Polyurethanes as Robust HCl Corrosion Inhibitor Mediated by Inter/intramolecular Hydrogen Bond.  ACS Applied Polymer Materials,  (5): (3844–3854). 
21. Wang Lu-Ping, Zhang Ming-Guang, Hao Jing-Cheng, Wang Xu.  (2022)  Insertion of Supramolecular Segments into Covalently Crosslinked Polyurethane Networks towards the Fabrication of Recyclable Elastomers.  CHINESE JOURNAL OF POLYMER SCIENCE,  40  (3): (321-330). 
22. Jingjing Bai, Jingjing Cui, Yidan Ma, Wenhao Zhao, Yulong Wang, Zhenzhong Li.  (2022)  Orange emissive N-doped carbon dots and their application in detection of water in organic solvents and the polyurethane composites.  OPTICAL MATERIALS,  123  (111927). 
23. Shanjun Ding, Zhu Wang, Guocui Zhu, Ximing Zhang, Jun Zhang, Yanjie Zhang, Zhuoqi Cen, Lin Zhou, Yunjun Luo.  (2021)  Accelerating Self-Healing Driven by Surface Energy Using Bulky Ester Groups in Polymer Materials.  Journal of Physical Chemistry C,  125  (51): (28048–28058). 
24. Jun Xu, Tiantian Hao, Changlin Liu, Jingjing Bi, Jing Sun, Zheng Wen, Zhaosheng Hou, Jinjian Wei.  (2021)  pH-Responsive and degradable polyurethane film with good tensile properties for drug delivery in vitro.  Materials Today Communications,  29  (102969). 
25. Yinglu Sun, Dekun Sheng, Haohao Wu, Xinxin Tian, Haopu Xie, Biru Shi, Xiangdong Liu, Yuming Yang.  (2021)  Bio-based vitrimer-like polyurethane based on dynamic imine bond with high-strength, reprocessability, rapid-degradability and antibacterial ability.  POLYMER,  233  (124208). 
26. Xing-Ya Liu, Rui-Yang Xie, Tao Chen, Lei He, Ting Wang, Wang Liao, Zhi-Guo Liu, Ming-Jun Chen.  (2021)  Improvement of polyurethane film strength by H-bonding crosslinking with hydroxylated melamine.  JOURNAL OF APPLIED POLYMER SCIENCE,  138  (47): (51411). 
27. Shanjun Ding, Jun Zhang, Guocui Zhu, Xin Ren, Lin Zhou, Yunjun Luo.  (2021)  Rationally Constructed Surface Energy and Dynamic Hard Domains Balance Mechanical Strength and Self-Healing Efficiency of Energetic Linear Polymer Materials.  LANGMUIR,  37  (30): (8997–9008). 
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29. Yaofang Hu, Gang Tang, Yunjun Luo, Shumeng Chi, Xiaoyu Li.  (2021)  Glycidyl azide polymer-based polyurethane vitrimers with disulfide chain extenders.  Polymer Chemistry,  12  (28): (4072-4082). 
30. Haohao Wu, Xiangdong Liu, Dekun Sheng, Yan Zhou, Shaobin Xu, Haopu Xie, Xinxin Tian, Yinglu Sun, Biru Shi, Yuming Yang.  (2021)  High performance and near body temperature induced self-healing thermoplastic polyurethane based on dynamic disulfide and hydrogen bonds.  POLYMER,  214  (123261). 
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32. Jingjing Bai, Weijie Ren, Yulong Wang, Xiaoxia Li, Cheng Zhang, Zhenzhong Li, Zhongyuan Xie.  (2020)  High-performance thermoplastic polyurethane elastomer/carbon dots bulk nanocomposites with strong luminescence.  HIGH PERFORMANCE POLYMERS,     
33. Maochen Liu, Jiang Zhong, Zijian Li, Jinchuang Rong, Kun Yang, Jiyong Zhou, Liang Shen, Fei Gao, Xuelong Huang, Haifeng He.  (2020)  A high stiffness and self-healable polyurethane based on disulfide bonds and hydrogen bonding.  EUROPEAN POLYMER JOURNAL,  124  (109475). 
34. Yanpeng Cao, Rui Yan, Xiaoye Wo, Jinlong Ma, Xiao Yu, Aijun Li, Jian Huang, Fenghua Li, Qixian Zhang.  (2024)  A self-healing elastomer with outstanding mechanical properties was designed based on urea bonds.  Journal of Materials Chemistry C,  12  (26): (9685-9692). 
35. Jinbiao Zhao, Huimin Duan, Xinxin Xu, Shangchao Ji, Hao Yang, Zhichao Huang, Qi Zhong, Dongming Qi.  (2025)  Balancing flame retardancy and high toughness in solvent-free reactive polyurethane films via P/Si synergistic strategy.  EUROPEAN POLYMER JOURNAL,  228  (113810). 
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