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Dichloromethylenediphosphonic acid disodium salt - 10mM in Water, high purity , CAS No.22560-50-5
ATP-ADP transporter inhibitor
Basic Description
Synonyms
CLODRONATE DISODIUM | Clodronic acid disodium salt | 22560-50-5 | Disodium clodronate | Clasteon | Loron | Lodronate | Ostac | Sodium clodronate | Mebonat | Ossiten | Clodronate sodium | Chlodronate sodium | Bonefos | Clodron | Dichloromethane diphosphonate | Clodronate disodium anhydro
Specifications & Purity
10mM in Water
Biochemical and Physiological Mechanisms
ATP-ADP transporter inhibitor. Inhibits bone resorption and soft tissue calcification. Encapsulated in liposomes, depletes macrophages in vivo . Induces apoptosis in osteoclasts.
Storage Temp
Store at -80°C
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Taxonomic Classification
Kingdom
Organic compounds
Superclass
Organic acids and derivatives
Class
Organic phosphonic acids and derivatives
Subclass
Bisphosphonates
Intermediate Tree Nodes
Not available
Direct Parent
Bisphosphonates
Alternative Parents
Organic phosphonic acids Organic metal halides Organopnictogen compounds Organophosphorus compounds Organochlorides Organic sodium salts Organic oxides Hydrocarbon derivatives Alkyl chlorides
Molecular Framework
Aliphatic acyclic compounds
Substituents
Bisphosphonate - Organophosphonic acid - Organic metal halide - Organic alkali metal salt - Alkyl chloride - Hydrocarbon derivative - Organic oxide - Organic sodium salt - Organic salt - Organophosphorus compound - Organochloride - Organopnictogen compound - Organohalogen compound - Organic oxygen compound - Alkyl halide - Aliphatic acyclic compound
Description
This compound belongs to the class of organic compounds known as bisphosphonates. These are organic compounds containing two phosphonate groups linked together through a carbon atoms.
External Descriptors
one-carbon compound - organic sodium salt
Data sources
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
Associated Targets(Human)
Associated Targets(non-human)
Mechanisms of Action
Mechanism of Action
Action Type
target ID
Target Name
Target Type
Target Organism
Binding Site Name
References
Names and Identifiers
IUPAC Name
disodium;[dichloro-[hydroxy(oxido)phosphoryl]methyl]-hydroxyphosphinate
INCHI
InChI=1S/CH4Cl2O6P2.2Na/c2-1(3,10(4,5)6)11(7,8)9;;/h(H2,4,5,6)(H2,7,8,9);;/q;2*+1/p-2
InChIKey
HJKBJIYDJLVSAO-UHFFFAOYSA-L
Smiles
C(P(=O)(O)[O-])(P(=O)(O)[O-])(Cl)Cl.[Na+].[Na+]
Isomeric SMILES
C(P(=O)(O)[O-])(P(=O)(O)[O-])(Cl)Cl.[Na+].[Na+]
WGK Germany
3
RTECS
SZ7640700
Alternate CAS
88416-50-6
Molecular Weight
288.86
Certificates（CoA,COO,BSE/TSE and Analysis Chart)
Chemical and Physical Properties
Molecular Weight
288.850 g/mol
XLogP3
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
6
Rotatable Bond Count
2
Exact Mass
287.85 Da
Monoisotopic Mass
287.85 Da
Topological Polar Surface Area
121.000 Ų
Heavy Atom Count
13
Formal Charge
0
Complexity
206.000
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
The total count of all stereochemical bonds
0
Covalently-Bonded Unit Count
3
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