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Desonide - 10mM in DMSO, high purity , CAS No.638-94-8(DMSO), Glucocorticoid receptor agonist
Glucocorticoid Receptor Agonists
Basic Description
| Synonyms |
(11β,16α)-11,21-dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]-pregna-1,4-diene-3,20-dione |
| Specifications & Purity |
Moligand™, 10mM in DMSO |
| Biochemical and Physiological Mechanisms |
Desonide is a low potency topical corticosteroid. |
| Storage Temp |
Store at -80°C |
| Shipped In |
Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available. |
| Grade |
Moligand™ |
| Action Type |
AGONIST |
| Mechanism of action |
Glucocorticoid receptor agonist |
| Product Description |
Information Desonide Desonide is a low potency topical corticosteroid.
In vitro
In vivo
Cell Data
cell lines：MCF-7, SW620, K562, SK-MEL-5 and A375 cancer cell lines Concentrations： Incubation Time： Powder Purity:≥99%
|
Product Properties
| ALogP |
1.028 |
| hba_count |
4 |
| HBD Count |
2 |
| Rotatable Bond |
2 |
Names and Identifiers
| Smiles |
CC1(C)OC2CC3C4CCC5=CC(=O)C=CC5(C)C4C(O)CC3(C)C2(O1)C(=O)CO |
| Molecular Weight |
416.51 |
| Reaxy-Rn |
356665 |
| Reaxys-RN_link_address |
https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=356665&ln= |
Certificates（CoA,COO,BSE/TSE and Analysis Chart)
Chemical and Physical Properties
| DMSO(mg / mL) Max Solubility |
83 |
| DMSO(mM) Max Solubility |
199.27 |
| Water(mg / mL) Max Solubility |
<1 |
Citations of This Product
|
1.
Liheng Gao, Xingxing Liu, Wenshuo Zhao, Chaojin Li, Fujun Wang, Jing Gao, Xinqin Liao, Lei Wei, Hao Wu, Yuanjin Zheng, Lu Wang.
(2022)
Extracellular-matrix-mimicked 3D nanofiber and hydrogel interpenetrated wound dressing with a dynamic autoimmune-derived healing regulation ability based on wound exudate.
Biofabrication,
15
(1):
(15021).
|
|
2.
Yangjie LI, Jiaying HUANG, Jihui FANG, Zhiye HUANG.
(2022)
[Fast screening and confirmation of 73 common prohibited compounds in cosmetics by ultra performance liquid chromatography-quadrupole-time-of-flight high resolution mass spectrometry]..
Chinese Journal of Chromatography,
40
(5):
(433-442).
|
|
3.
Yanxia Li, Xiaoman Chen, Ling Xia, Xiaohua Xiao, Gongke Li.
(2019)
Magnetic metal-organic frameworks-101 functionalized with graphite-like carbon nitride for the efficient enrichment of glucocorticoids in cosmetics.
JOURNAL OF CHROMATOGRAPHY A,
1606
(460382).
|
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3 Citations