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desirudin, Inhibitor of coagulation factor II; thrombin, CAS No.120993-53-5, Inhibitor of coagulation factor II; thrombin

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Item Number
rp173871
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Price Qty
rp173871-500μg
500μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,334.90
rp173871-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,334.90

Basic Description

Product Name desirudin, Inhibitor of coagulation factor II; thrombin, CAS No.120993-53-5
Synonyms Revasc | Desirudin [USAN:INN:BAN] | recombinant HV1 hirudin | 63-Desulfohirudin (recombinant) | 63-Desulfohirudin(Hirudo medicinalis isoform HV1) | UNII-U0JZ726775 | DESIRUDIN (MART.) | IK-HIR02 | DTXCID9075585 | Desirudin | 63-Desulfohirudin | CGP39393 |
Grade Moligand™
Specifications & Purity Moligand™
Action Type INHIBITOR
Mechanism of action Inhibitor of coagulation factor II; thrombin

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
Superclass Organic Polymers
Class Polypeptides
Subclass Not available
Intermediate Tree Nodes Not available
Direct Parent Polypeptides
Alternative Parents Cyclic peptides  Tyrosine and derivatives  Phenylalanine and derivatives  Histidine and derivatives  Glutamic acid and derivatives  Glutamine and derivatives  Asparagine and derivatives  Aspartic acid and derivatives  Isoleucine and derivatives  Leucine and derivatives  Valine and derivatives  Proline and derivatives  Macrolactams  N-acyl-L-glutamines  Serine and derivatives  Alpha amino acid amides  Amphetamines and derivatives  N-acylpyrrolidines  Pyrrolidinecarboxamides  1-hydroxy-2-unsubstituted benzenoids  N-acyl amines  Tertiary carboxylic acid amides  Heteroaromatic compounds  Imidazoles  Organic disulfides  Amino acids  Primary carboxylic acid amides  Secondary carboxylic acid amides  Secondary alcohols  Lactams  Azacyclic compounds  Carboxylic acids  Carbonyl compounds  Organic oxides  Primary alcohols  Monoalkylamines  Organopnictogen compounds  Hydrocarbon derivatives  
Molecular Framework Aromatic heteropolycyclic compounds
Substituents Polypeptide - Cyclic alpha peptide - Tyrosine or derivatives - Phenylalanine or derivatives - Histidine or derivatives - Glutamic acid or derivatives - Glutamine or derivatives - Asparagine or derivatives - Aspartic acid or derivatives - Isoleucine or derivatives - Leucine or derivatives - N-acyl-l-alpha-amino acid - N-acyl-alpha amino acid or derivatives - Macrolactam - N-acyl-alpha-amino acid - Valine or derivatives - Proline or derivatives - Alpha-amino acid amide - N-acyl-l-glutamine - Serine or derivatives - Amphetamine or derivatives - Alpha-amino acid or derivatives - N-substituted-alpha-amino acid - N-acylpyrrolidine - Pyrrolidine carboxylic acid or derivatives - Pyrrolidine-2-carboxamide - Phenol - 1-hydroxy-2-unsubstituted benzenoid - Fatty amide - N-acyl-amine - Monocyclic benzene moiety - Benzenoid - Fatty acyl - Pyrrolidine - Tertiary carboxylic acid amide - Heteroaromatic compound - Imidazole - Azole - Secondary carboxylic acid amide - Secondary alcohol - Primary carboxylic acid amide - Amino acid - Amino acid or derivatives - Organic disulfide - Lactam - Carboxamide group - Carboxylic acid derivative - Azacycle - Carboxylic acid - Organoheterocyclic compound - Organic nitrogen compound - Organic oxide - Primary aliphatic amine - Hydrocarbon derivative - Carbonyl group - Alcohol - Organonitrogen compound - Organopnictogen compound - Organooxygen compound - Amine - Organic oxygen compound - Primary alcohol - Primary amine - Aromatic heteropolycyclic compound
Description This compound belongs to the class of organic compounds known as polypeptides. These are peptides containing ten or more amino acid residues.
External Descriptors Not available

Associated Targets(Human)

F2 Tclin Prothrombin (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Storage and Shipping

CAS 120993-53-5

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Genetic information

Alternate Names Revasc | Desirudin [USAN:INN:BAN] | recombinant HV1 hirudin | 63-Desulfohirudin (recombinant) | 63-Desulfohirudin(Hirudo medicinalis isoform HV1) | UNII-U0JZ726775 | DESIRUDIN (MART.) | IK-HIR02 | DTXCID9075585 | Desirudin | 63-Desulfohirudin | CGP39393 |
Reference
  • 1. Kinetics and inhibition of recombinant human cystathionine gamma-lyase. Toward the rational control of transsulfuration., The Journal of biological chemistry, Steegborn, C C and 7 more authors.
  • 2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences., Proceedings of the National Academy of Sciences of the United States of America, Strausberg, Robert L RL and 83 more authors.
  • 3. Genomic basis of cystathioninuria (MIM 219500) revealed by multiple mutations in cystathionine gamma-lyase (CTH)., Human genetics, Wang, Jian J and Hegele, Robert A RA.
  • 4. Cloning and nucleotide sequence of human liver cDNA encoding for cystathionine gamma-lyase., Biochemical and biophysical research communications, Lu, Y Y, O'Dowd, B F BF, Orrego, H H and Israel, Y Y.
  • 5. Single nucleotide polymorphism in CTH associated with variation in plasma homocysteine concentration., Clinical genetics, Wang, J J, Huff, A M AM, Spence, J D JD and Hegele, R A RA.
  • 6. Cystathionine gamma-lyase overexpression inhibits cell proliferation via a H2S-dependent modulation of ERK1/2 phosphorylation and p21Cip/WAK-1., The Journal of biological chemistry, Yang, Guangdong G, Cao, Kun K, Wu, Lingyun L and Wang, Rui R.
  • 7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)., Genome research, Gerhard, Daniela S DS and 115 more authors.
  • 8. Towards a proteome-scale map of the human protein-protein interaction network., Nature, Rual, Jean-François JF and 37 more authors.
  • 9. The DNA sequence and biological annotation of human chromosome 1., Nature, Gregory, S G SG and 178 more authors.
  • 10. Polymorphisms in one-carbon metabolism and trans-sulfuration pathway genes and susceptibility to bladder cancer., International journal of cancer, Moore, Lee E LE and 14 more authors. more

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