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Deferoxamine mesylate - ≥98%, high purity , Iron chelating agent, CAS No.138-14-7, Iron chelating agent

10 Citations COA COA
    Grade & Purity:
  • ≥98%
In stock
Item Number
D302525
Grouped product items
SKU Size
Availability
 Price Qty
D302525-5mg
5mg
10
$9.90
D302525-25mg
25mg
8
$19.90
D302525-100mg
100mg
3
$44.90
D302525-250mg
250mg
1
$89.90
D302525-500mg
500mg
4
$159.90
D302525-1g
1g
4
$279.90
D302525-5g
5g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$1,299.90
Wish List
Bulk Order  SDS  DATASHEET  Specification Sheet

Iron chelator

View related series
Akt (180) Apoptosis (4276) Autophagy (1917) Glucose Metabolism (1943) HIF/HIF Prolyl-Hydroxylase (128) Immunology/Inflammation (1929) Metabolic Enzyme/Protease (4860) NF-κB (747) PI3K/Akt/mTOR (765) Reactive Oxygen Species (309)

Basic Description

Synonyms Deferoxamine mesilate | Deferoxamine mesylate | Deferoxamine methanesulfonate | Desferrioxamine B mesylate
Specifications & Purity ≥98%
Biochemical and Physiological Mechanisms Iron chelator. Blood-brain barrier permeable. Displays a number of biological actions such as immunomodulation, inhibition of inflammation and atherosclerosis, and reduction of neuronal death.
Storage Temp Store at -20°C,Argon charged
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Action Type CHELATING AGENT
Mechanism of action Iron chelating agent
Note Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
Superclass Organic acids and derivatives
Class Organic sulfonic acids and derivatives
Subclass Organosulfonic acids and derivatives
Intermediate Tree Nodes Not available
Direct Parent Organosulfonic acids
Alternative Parents Sulfonyls  Methanesulfonates  Alkanesulfonic acids  Acetohydroxamic acids  Acetamides  Amino acids and derivatives  Propargyl-type 1,3-dipolar organic compounds  Carboximidic acids  Organopnictogen compounds  Organic oxides  Monoalkylamines  Hydrocarbon derivatives  Carbonyl compounds  
Molecular Framework Not available
Substituents Methanesulfonate - Organosulfonic acid - Sulfonyl - Acetohydroxamic acid - Acetamide - Alkanesulfonic acid - Amino acid or derivatives - Hydroxamic acid - Carboximidic acid - Carboximidic acid derivative - Carboxylic acid derivative - Organic 1,3-dipolar compound - Propargyl-type 1,3-dipolar organic compound - Organosulfur compound - Organooxygen compound - Organonitrogen compound - Primary aliphatic amine - Organopnictogen compound - Organic oxygen compound - Organic nitrogen compound - Amine - Primary amine - Organic oxide - Hydrocarbon derivative - Carbonyl group - Aliphatic acyclic compound
Description This compound belongs to the class of organic compounds known as organosulfonic acids. These are compounds containing the sulfonic acid group, which has the general structure RS(=O)2OH (R is not a hydrogen atom).
External Descriptors methanesulfonate salt

Associated Targets(Human)

PLK1 Tchem Serine/threonine-protein kinase PLK1 (28605 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
GAA Tclin Lysosomal alpha-glucosidase (35701 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
MDH1 Tchem Malate dehydrogenase cytoplasmic (119 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CYP2D6 Tclin Cytochrome P450 2D6 (33882 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CTRC Tchem Chymotrypsin C (381 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CYP1A2 Tchem Cytochrome P450 1A2 (26471 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CYP2C9 Tchem Cytochrome P450 2C9 (32119 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CYP2C19 Tchem Cytochrome P450 2C19 (29246 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CYP3A4 Tclin Cytochrome P450 3A4 (53859 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
HEK293 (82097 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
KDM4E Tchem Lysine-specific demethylase 4D-like (40243 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
SMN1 Tchem Survival motor neuron protein (34246 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
LMNA Tbio Prelamin-A/C (36751 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
GMNN Tbio Geminin (128009 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
SLCO1B1 Tchem Solute carrier organic anion transporter family member 1B1 (2672 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CBX1 Tbio Chromobox protein homolog 1 (92434 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ATAD5 Tbio ATPase family AAA domain-containing protein 5 (122566 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
SLCO1B3 Tchem Solute carrier organic anion transporter family member 1B3 (2517 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
GLS Tchem Glutaminase kidney isoform, mitochondrial (16997 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Associated Targets(non-human)

ampC Beta-lactamase AmpC (62480 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Plasmodium falciparum (966862 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Serine/threonine-protein phosphatase (23 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Nfe2l2 Nuclear factor erythroid 2-related factor 2 (214 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
fba Putative fructose-1,6-bisphosphate aldolase (15559 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ffp 4'-phosphopantetheinyl transferase ffp (24982 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ATP-dependent molecular chaperone HSP82 (2186 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
FTL Ferritin light chain (43324 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Names and Identifiers

Pubchem Sid 504753887
Pubchem Sid Url https://pubchem.ncbi.nlm.nih.gov/substance/504753887
IUPAC Name N-[5-[[4-[5-[acetyl(hydroxy)amino]pentylamino]-4-oxobutanoyl]-hydroxyamino]pentyl]-N'-(5-aminopentyl)-N'-hydroxybutanediamide;methanesulfonic acid
INCHI InChI=1S/C25H48N6O8.CH4O3S/c1-21(32)29(37)18-9-3-6-16-27-22(33)12-14-25(36)31(39)20-10-4-7-17-28-23(34)11-13-24(35)30(38)19-8-2-5-15-26;1-5(2,3)4/h37-39H,2-20,26H2,1H3,(H,27,33)(H,28,34);1H3,(H,2,3,4)
InChIKey IDDIJAWJANBQLJ-UHFFFAOYSA-N
Smiles CC(=O)N(CCCCCNC(=O)CCC(=O)N(CCCCCNC(=O)CCC(=O)N(CCCCCN)O)O)O.CS(=O)(=O)O
Isomeric SMILES CC(=O)N(CCCCCNC(=O)CCC(=O)N(CCCCCNC(=O)CCC(=O)N(CCCCCN)O)O)O.CS(=O)(=O)O
Molecular Weight 656.79
Reaxy-Rn 4122177
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=4122177&ln=

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

56 results found

Lot Number Certificate Type Date Item
F2511307 Certificate of Analysis May 21, 2025 D302525
F2511308 Certificate of Analysis May 21, 2025 D302525
F2511309 Certificate of Analysis May 21, 2025 D302525
F2511310 Certificate of Analysis May 21, 2025 D302525
F2511311 Certificate of Analysis May 21, 2025 D302525
F2511312 Certificate of Analysis May 21, 2025 D302525
F2511313 Certificate of Analysis May 21, 2025 D302525
F2509041 Certificate of Analysis Jun 29, 2024 D302525
G2408414 Certificate of Analysis Jun 29, 2024 D302525
G2408420 Certificate of Analysis Jun 29, 2024 D302525
G2408426 Certificate of Analysis Jun 29, 2024 D302525
G2408427 Certificate of Analysis Jun 29, 2024 D302525
G2408429 Certificate of Analysis Jun 29, 2024 D302525
G2408430 Certificate of Analysis Jun 29, 2024 D302525
G2408431 Certificate of Analysis Jun 29, 2024 D302525
L2419409 Certificate of Analysis Jun 29, 2024 D302525
C2416202 Certificate of Analysis Mar 07, 2024 D302525
C2416204 Certificate of Analysis Mar 07, 2024 D302525
C2416206 Certificate of Analysis Mar 07, 2024 D302525
C2416207 Certificate of Analysis Mar 07, 2024 D302525
C2416208 Certificate of Analysis Mar 07, 2024 D302525
C2416210 Certificate of Analysis Mar 07, 2024 D302525
C2416212 Certificate of Analysis Mar 07, 2024 D302525
J2331321 Certificate of Analysis Oct 21, 2023 D302525
J2331416 Certificate of Analysis Oct 21, 2023 D302525
A2415184 Certificate of Analysis Oct 21, 2023 D302525
L2322155 Certificate of Analysis Oct 21, 2023 D302525
J2331320 Certificate of Analysis Oct 21, 2023 D302525
J2331417 Certificate of Analysis Oct 21, 2023 D302525
J2331322 Certificate of Analysis Oct 21, 2023 D302525
J2331418 Certificate of Analysis Oct 21, 2023 D302525
J2331415 Certificate of Analysis Oct 21, 2023 D302525
G2307270 Certificate of Analysis Jun 12, 2023 D302525
G2307301 Certificate of Analysis Jun 12, 2023 D302525
G2307275 Certificate of Analysis Jun 12, 2023 D302525
G2307269 Certificate of Analysis Jun 12, 2023 D302525
G2307271 Certificate of Analysis Jun 12, 2023 D302525
G2307273 Certificate of Analysis Jun 12, 2023 D302525
G2307272 Certificate of Analysis Jun 12, 2023 D302525
G2307279 Certificate of Analysis Jun 12, 2023 D302525
G2307274 Certificate of Analysis Jun 12, 2023 D302525
G2307276 Certificate of Analysis Jun 12, 2023 D302525
I2306034 Certificate of Analysis Jun 12, 2023 D302525
B2310544 Certificate of Analysis Feb 01, 2023 D302525
B2310545 Certificate of Analysis Feb 01, 2023 D302525
B2310546 Certificate of Analysis Feb 01, 2023 D302525
B2310543 Certificate of Analysis Feb 01, 2023 D302525
B23101012 Certificate of Analysis Feb 01, 2023 D302525
D2318960 Certificate of Analysis Feb 01, 2023 D302525
B2310542 Certificate of Analysis Feb 01, 2023 D302525
H2217340 Certificate of Analysis Aug 01, 2022 D302525
H2217341 Certificate of Analysis Aug 01, 2022 D302525
H2217342 Certificate of Analysis Aug 01, 2022 D302525
H2217343 Certificate of Analysis Aug 01, 2022 D302525
H2217345 Certificate of Analysis Aug 01, 2022 D302525
H2217334 Certificate of Analysis Aug 01, 2022 D302525

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Chemical and Physical Properties

Sensitivity Moisture sensitive、Air sensitive、Heat sensitive
Molecular Weight 656.800 g/mol
XLogP3
Hydrogen Bond Donor Count 7
Hydrogen Bond Acceptor Count 12
Rotatable Bond Count 23
Exact Mass 656.341 Da
Monoisotopic Mass 656.341 Da
Topological Polar Surface Area 269.000 Ų
Heavy Atom Count 44
Formal Charge 0
Complexity 832.000
Isotope Atom Count 0
Defined Atom Stereocenter Count 0
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
The total count of all stereochemical bonds 0
Covalently-Bonded Unit Count 2

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Citations of This Product

How to Cite Aladdin Scientific Products?
1. Haoze Song, Jing Liang, Yuanyuan Guo, Yang Liu, Kuiru Sa, Guohong Yan, Wen Xu, Wei Xu, Lixia Chen, Hua Li.  (2024)  A potent GPX4 degrader to induce ferroptosis in HT1080 cells.  EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY,  265  (116110). 
2. Weimin Yin, Jiao Chang, Jiuyuan Sun, Yuge Zhao, Shiyu Chen, Hui Zhi, Jie Zang, Tingting Zhang, Yongyong Li, Haiqing Dong.  (2024)  Arginine nanoparticles mediated closed-loop ferroptosis enhancement for T cell activity boosting in cancer immunotherapy.  Applied Materials Today,  36  (102047). 
3. Wang Shengmei, Guo Qiuyan, Xu Rubing, Lin Peng, Deng Guoyan, Xia Xinhua.  (2023)  Combination of ferroptosis and pyroptosis dual induction by triptolide nano-MOFs for immunotherapy of Melanoma.  JOURNAL OF NANOBIOTECHNOLOGY,  21  (1): (1-21). 
4. Shan Gao, Wanlin Zhang, Xingxing Zhai, Xue Zhao, Jianxin Wang, Jie Weng, Jianshu Li, Xingyu Chen.  (2023)  An antibacterial and proangiogenic double-layer drug-loaded microneedle patch for accelerating diabetic wound healing.  Biomaterials Science,  11  (2): (533-541). 
5. Kai Sun, Jiaying Yu, Jinzhong Hu, Jian Chen, Jia Song, Zhixin Chen, Zhuoer Cai, Zhuoxuan Lu, Liming Zhang, Zhifei Wang.  (2022)  Salicylic acid-based hypoxia-responsive chemodynamic nanomedicines boost antitumor immunotherapy by modulating immunosuppressive tumor microenvironment.  Acta Biomaterialia,  148  (230). 
6. Xueyang Jin, Ming Zhang, Jinghui Lu, Ximeng Duan, Jinyao Chen, Yue Liu, Wenqiang Chang, Hongxiang Lou.  (2021)  Hinokitiol chelates intracellular iron to retard fungal growth by disturbing mitochondrial respiration.  Journal of Advanced Research,  34  (65). 
7. Fanjia Dai, Jiaying Zhang, Fengjiao Chen, Xianwu Chen, Celine Jessica Lee, Hongze Liang, Lingling Zhao, Hui Tan.  (2024)  A Multi-Responsive Hydrogel Combined With Mild Heat Stimulation Promotes Diabetic Wound Healing by Regulating Inflammatory and Enhancing Angiogenesis.  Advanced Science,    (2408783). 
8. Yupei Sun, Qin Lu, Die Dong, Rimei Chen, Zhiping Chen, Zhen Xie, Hongxiang Zhu, Qing Bu, Hui He, Shuangfei Wang.  (2024)  Engineering a monitoring-therapeutic in situ hydrogel via a cellulose-integrated nanointerface.  CHEMICAL ENGINEERING JOURNAL,  482  (149015). 
9. Wajiha Ahmed, Shifen Li, Min Liang, Yongyuan Kang, Xiaoqing Liu, Changyou Gao.  (2024)  Multifunctional Drug- and AuNRs-Loaded ROS-Responsive Selenium-Containing Polyurethane Nanofibers for Smart Wound Healing.  ACS Biomaterials Science & Engineering,  10  (6): (3946-3957). 
10. Weichen Sun, Xiaoting Zuo, Yu Zhang, Chengyan Zhou, Shuai Guo, Wenjuan Li, Mingtao Run, Jianglei Qin.  (2024)  Quaternary ammonium grafted chitosan hydrogel with enhanced antibacterial performance as tannin acid and deferoxamine carrier to promote diabetic wound healing.  COLLOIDS AND SURFACES B-BIOINTERFACES,  244  (114160). 

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