This is a demo store. No orders will be fulfilled.

DBCO-Amine - ≥95%, high purity , CAS No.1255942-06-3

    Grade & Purity:
  • ≥95%
In stock
Item Number
D752665
Grouped product items
SKU Size
Availability
Price Qty
D752665-250mg
250mg
2
$99.90
D752665-1g
1g
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$329.90

Basic Description

Synonyms DBCO-NH2 | CS-W000423 | 1255942-06-3 | ADIBO-amine | Dibenzocyclooctyne-amine | PD171600 | Azadibenzocyclooctyne-amine
Specifications & Purity ≥95%
Storage Temp Protected from light,Store at -20°C,Argon charged
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Product Description

DBCO Amine is a simple DBCO-containing building block used to derivatize carboxyl groups in the presence of activators (e.g. EDC, or DCC) or activated esters (e.g. NHS esters) with DBCO moiety through a stable amide bond.|DBCO reagents, also know as ADIBO or DIBAC are the most commonly used substrates for copper-free click reaction. DBCO compounds react with azide functionalized compounds or biomolecules without the need for a Cu(I) catalyst to result in a stable triazole linkage.

Product Application

Azadibenzocyclooctyne amine is a carbonyl reactive reagent used to incorporate ADIBO into organic compounds, surfaces or particlesAzadibenzocyclooctyne amine is widely useful in strain-promoted copper-free azide-alkyne cycloaddition reactions. It reacts with azide functionalized compounds or bimolecules to give stable triazole linkage without a need for a Cu(I) catalyst.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
Superclass Organic acids and derivatives
Class Carboxylic acids and derivatives
Subclass Amino acids, peptides, and analogues
Intermediate Tree Nodes Amino acids and derivatives
Direct Parent Beta amino acids and derivatives
Alternative Parents Benzenoids  Tertiary carboxylic acid amides  Azacyclic compounds  Organic oxides  Monoalkylamines  Hydrocarbon derivatives  Carbonyl compounds  
Molecular Framework Aromatic heteropolycyclic compounds
Substituents Beta amino acid or derivatives - Benzenoid - Tertiary carboxylic acid amide - Carboxamide group - Organoheterocyclic compound - Azacycle - Hydrocarbon derivative - Organic oxide - Primary amine - Organooxygen compound - Organonitrogen compound - Primary aliphatic amine - Organic oxygen compound - Carbonyl group - Organic nitrogen compound - Amine - Aromatic heteropolycyclic compound
Description This compound belongs to the class of organic compounds known as beta amino acids and derivatives. These are amino acids having a (-NH2) group attached to the beta carbon atom.
External Descriptors Not available

Associated Targets(Human)

MCF7 (126967 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Names and Identifiers

Pubchem Sid 504772406
Pubchem Sid Url https://pubchem.ncbi.nlm.nih.gov/substance/504772406
IUPAC Name 3-amino-1-(2-azatricyclo[10.4.0.04,9]hexadeca-1(16),4,6,8,12,14-hexaen-10-yn-2-yl)propan-1-one
INCHI InChI=1S/C18H16N2O/c19-12-11-18(21)20-13-16-7-2-1-5-14(16)9-10-15-6-3-4-8-17(15)20/h1-8H,11-13,19H2
InChIKey OCCYFTDHSHTFER-UHFFFAOYSA-N
Smiles C1C2=CC=CC=C2C#CC3=CC=CC=C3N1C(=O)CCN
Isomeric SMILES C1C2=CC=CC=C2C#CC3=CC=CC=C3N1C(=O)CCN
Molecular Weight 276.33
Reaxy-Rn 21543048
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=21543048&ln=

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

4 results found

Lot Number Certificate Type Date Item
K2422407 Certificate of Analysis Nov 18, 2024 D752665
K2422431 Certificate of Analysis Nov 18, 2024 D752665
K2422429 Certificate of Analysis Nov 18, 2024 D752665
K2422430 Certificate of Analysis Nov 18, 2024 D752665

Chemical and Physical Properties

Sensitivity Heat & light sensitive
Melt Point(°C) 86-96° C
Molecular Weight 276.300 g/mol
XLogP3 1.900
Hydrogen Bond Donor Count 1
Hydrogen Bond Acceptor Count 2
Rotatable Bond Count 2
Exact Mass 276.126 Da
Monoisotopic Mass 276.126 Da
Topological Polar Surface Area 46.300 Ų
Heavy Atom Count 21
Formal Charge 0
Complexity 447.000
Isotope Atom Count 0
Defined Atom Stereocenter Count 0
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
The total count of all stereochemical bonds 0
Covalently-Bonded Unit Count 1

Citations of This Product

1. Yueping Li, Shanshan Shan, Ruru Zhang, Chaoping Sun, Xuelan Hu, Jiada Fan, Yi Wang, Ruixue Duan, Mingyuan Gao.  (2024)  Imaging and Downstaging Bladder Cancer with the 177Lu-Labeled Bioorthogonal Nanoprobe.  ACS Nano,  18  (26): (17209-17217). 

Solution Calculators

Reviews

Customer Reviews

Shall we send you a message when we have discounts available?

Remind me later

Thank you! Please check your email inbox to confirm.

Oops! Notifications are disabled.