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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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D752665-250mg
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250mg |
2
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$99.90
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D752665-1g
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1g |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$329.90
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| Synonyms | DBCO-NH2 | CS-W000423 | 1255942-06-3 | ADIBO-amine | Dibenzocyclooctyne-amine | PD171600 | Azadibenzocyclooctyne-amine |
|---|---|
| Specifications & Purity | ≥95% |
| Storage Temp | Protected from light,Store at -20°C,Argon charged |
| Shipped In |
Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available. |
| Product Description |
DBCO Amine is a simple DBCO-containing building block used to derivatize carboxyl groups in the presence of activators (e.g. EDC, or DCC) or activated esters (e.g. NHS esters) with DBCO moiety through a stable amide bond.|DBCO reagents, also know as ADIBO or DIBAC are the most commonly used substrates for copper-free click reaction. DBCO compounds react with azide functionalized compounds or biomolecules without the need for a Cu(I) catalyst to result in a stable triazole linkage. Product Application Azadibenzocyclooctyne amine is a carbonyl reactive reagent used to incorporate ADIBO into organic compounds, surfaces or particlesAzadibenzocyclooctyne amine is widely useful in strain-promoted copper-free azide-alkyne cycloaddition reactions. It reacts with azide functionalized compounds or bimolecules to give stable triazole linkage without a need for a Cu(I) catalyst. |
Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Organic acids and derivatives |
| Class | Carboxylic acids and derivatives |
| Subclass | Amino acids, peptides, and analogues |
| Intermediate Tree Nodes | Amino acids and derivatives |
| Direct Parent | Beta amino acids and derivatives |
| Alternative Parents | Benzenoids Tertiary carboxylic acid amides Azacyclic compounds Organic oxides Monoalkylamines Hydrocarbon derivatives Carbonyl compounds |
| Molecular Framework | Aromatic heteropolycyclic compounds |
| Substituents | Beta amino acid or derivatives - Benzenoid - Tertiary carboxylic acid amide - Carboxamide group - Organoheterocyclic compound - Azacycle - Hydrocarbon derivative - Organic oxide - Primary amine - Organooxygen compound - Organonitrogen compound - Primary aliphatic amine - Organic oxygen compound - Carbonyl group - Organic nitrogen compound - Amine - Aromatic heteropolycyclic compound |
| Description | This compound belongs to the class of organic compounds known as beta amino acids and derivatives. These are amino acids having a (-NH2) group attached to the beta carbon atom. |
| External Descriptors | Not available |
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| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
| Pubchem Sid | 504772406 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/504772406 |
| IUPAC Name | 3-amino-1-(2-azatricyclo[10.4.0.04,9]hexadeca-1(16),4,6,8,12,14-hexaen-10-yn-2-yl)propan-1-one |
| INCHI | InChI=1S/C18H16N2O/c19-12-11-18(21)20-13-16-7-2-1-5-14(16)9-10-15-6-3-4-8-17(15)20/h1-8H,11-13,19H2 |
| InChIKey | OCCYFTDHSHTFER-UHFFFAOYSA-N |
| Smiles | C1C2=CC=CC=C2C#CC3=CC=CC=C3N1C(=O)CCN |
| Isomeric SMILES | C1C2=CC=CC=C2C#CC3=CC=CC=C3N1C(=O)CCN |
| Molecular Weight | 276.33 |
| Reaxy-Rn | 21543048 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=21543048&ln= |
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | Nov 18, 2024 | D752665 | |
| Certificate of Analysis | Nov 18, 2024 | D752665 | |
| Certificate of Analysis | Nov 18, 2024 | D752665 | |
| Certificate of Analysis | Nov 18, 2024 | D752665 |
| Sensitivity | Heat & light sensitive |
|---|---|
| Melt Point(°C) | 86-96° C |
| Molecular Weight | 276.300 g/mol |
| XLogP3 | 1.900 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 2 |
| Rotatable Bond Count | 2 |
| Exact Mass | 276.126 Da |
| Monoisotopic Mass | 276.126 Da |
| Topological Polar Surface Area | 46.300 Ų |
| Heavy Atom Count | 21 |
| Formal Charge | 0 |
| Complexity | 447.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
| 1. Yueping Li, Shanshan Shan, Ruru Zhang, Chaoping Sun, Xuelan Hu, Jiada Fan, Yi Wang, Ruixue Duan, Mingyuan Gao. (2024) Imaging and Downstaging Bladder Cancer with the 177Lu-Labeled Bioorthogonal Nanoprobe. ACS Nano, 18 (26): (17209-17217). |