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NGB 2904 and NGB 2849: two highly selective dopamine D3 receptor antagonists.

Basic Information

ID: ALA1130602

Journal: Bioorg Med Chem Lett

Title: NGB 2904 and NGB 2849: two highly selective dopamine D3 receptor antagonists.

Authors: Yuan J, Chen X, Brodbeck R, Primus R, Braun J, Wasley JW, Thurkauf A.

Abstract: N-(4-[4-¿2, 3-dichlorophenyl¿-1-piperazinyl]butyl)-3-fluorenylcarboxamide and N-(4-[4-¿2, 3-dichlorophenyl¿-1-piperazinyl]butyl)-2-biphenylenylcarboxamide were prepared in several steps from 2,3-dichloroaniline. These compounds were identified as highly selective dopamine D3 receptor antagonists.

CiteXplore: 9873609

DOI: 10.1016/s0960-894x(98)00469-7

Patent ID:

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